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Protein Isoforms
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Definition
: Different forms of a protein that may be produced from different GENES, or from the same gene by ALTERNATIVE SPLICING.
IM general only; coordinate NIM with specific protein (IM); for enzymes use ISOENZYMES
See Also
Alternative Splicing
;
RNA Splice Sites
Examples
Isoenzymes
Other names
Variants, Protein Splice; Isoforms, Protein; Protein Splice Variants; Splice Variants, Protein; Isoforms
Substance
CAS Registry & name
Categories
Source
Drugs
*
casein kinase 2, alpha, human
EC 2.7.11.1
Casein Kinase II
Protein Isoforms.
Mol Cell Biochem. 2011 Oct;356(1-2):57-65
RASSF1 protein, rat
0
*Tumor Suppressor Proteins
Protein Isoforms.
Biomed Environ Sci. 2011 Apr;24(2):163-71
CATP-
5 protein, C elegans
EC 3.6.1.-
*Adenosine Triphosphatases
*Membrane Proteins
*Caenorhabditis elegans Proteins
Protein Isoforms.
FASEB J. 2010 Jan;24(1):206-17
ssSPTa
EC 2.3.1.50
*Serine C-Palmitoyltransferase
Protein Isoforms.
Proc Natl Acad Sci U S A 2009 May 19;106(20):8186-91
DHRS4 protein, human
EC 1.1.1.184
*Oxidoreductases
Protein Isoforms.
Biosci Rep. 2009 Feb;29(1):47-56
strongylocin, Strongylocentrotus droebachiensis
0
*Antimicrobial Cationic Peptides
Sea Urchins
Protein Isoforms.
Dev Comp Immunol 2008;32(12):1430-40
nuclear coactivator p120, human
0
*Nuclear Proteins
*Transcription Factors
Protein Isoforms.
Endocr J 2008 Aug;55(4):657-65
COL4A3BP protein, zebrafish
EC 2.7.1.-
*Protein-Serine-Threonine Kinases
*Zebrafish Proteins
Protein Isoforms.
J Biol Chem 2008 Jul 18;283(29):20495-504
jaburetox-
2Ec, Canavalia ensiformis
EC 3.5.1.5
*Urease
Protein Isoforms.
Peptides 2007 Oct;28(10):2042-50
thymosin beta15, rat
0
*Thymosin
Protein Isoforms.
Ann N Y Acad Sci 2007 Sep;1112:286-96
periostin-
like factor, rat
0
*Muscle Proteins
*Cell Adhesion Molecules
Protein Isoforms.
Am J Physiol Cell Physiol 2007 May;292(5):C1672-80
CoAA protein, mouse
0
*Transcription Factors
Protein Isoforms.
Nucleic Acids Res 2007;35(6):1919-32
mechano-
growth factor, rat
0
*Insulin-Like Growth Factor I
Protein Isoforms.
J Physiol 1999 Apr 15;516( Pt 2):583-92
clusterin-
associated protein 1, human
0
*Antigens, Neoplasm
Protein Isoforms.
Int J Oncol 2007 Feb;30(2):461-7
DIDO1 protein, human
0
*DNA-Binding Proteins
Zinc Fingers
Protein Isoforms.
Proc Natl Acad Sci U S A 2007 Feb 20;104(8):2691-6
CaM-
KIIN protein, mouse
0
*Carrier Proteins
Calcium-Calmodulin-Dependent Protein Kinases/antagonists & inhibitors
Protein Isoforms.
Biochem Biophys Res Commun 2006 Nov 17;350(2):444-9
CSPP1 protein, human
0
*Microtubule-Associated Proteins
*Cell Cycle Proteins
Protein Isoforms.
J Cell Physiol 2006 Oct;209(1):199-210
AMPD1 protein, human
EC 3.5.4.6
*AMP Deaminase
Protein Isoforms.
Life Sci 2006 Sep 5;79(15):1413-8
Kv1.7 potassium channel, mouse
0
*Shaker Superfamily of Potassium Channels
Protein Isoforms.
J Gen Physiol 2006 Jul;128(1):133-45
heat shock 70-
kDa protein 8 isoform 1, human
0
*HSP70 Heat-Shock Proteins
*Protein Isoforms
Stem Cells.
Stem Cells 2005 Nov-Dec;23(10):1502-13
schlafen-
1 protein, mouse
0
*Cell Cycle Proteins
Protein Isoforms.
Immunity 1998 Nov;9(5):657-68
endoglin protein, mouse
0
*Intracellular Signaling Peptides and Proteins
Antigens, CD
Protein Isoforms.
Oncogene 2005 Jun 23;24(27):4450-61
SULT1 protein, zebrafish
EC 2.8.2.1
*Arylsulfotransferase
*Zebrafish Proteins
Protein Isoforms.
Arch Biochem Biophys 2005 May 1;437(1):10-9
ROBO3 protein, human
0
*Receptors, Immunologic
Nerve Tissue Proteins
Protein Isoforms.
Tsp68C protein, Drosophila
0
*Membrane Proteins
*Drosophila Proteins
Protein Isoforms.
Oncogene 2004 Dec 2;23(56):9120-8
Scylla protein, Drosophila
0
*Drosophila Proteins
Protein Isoforms.
Genes Dev 2004 Dec 1;18(23):2879-92
RASSF1 protein, mouse
0
*Tumor Suppressor Proteins
Protein Isoforms.
Cancer Res 2005 Jan 1;65(1):92-8
Fgf8 protein, mouse
0
*Fibroblast Growth Factor 8
Protein Isoforms.
Mt2 protein, Drosophila
EC 2.1.1.-
*DNA (Cytosine-5-)-Methyltransferase
*Drosophila Proteins
Protein Isoforms.
Macf1 protein, mouse
0
*Microfilament Proteins
Protein Isoforms.
Ctnna2 protein, mouse
0
*Nerve Tissue Proteins
*alpha Catenin
Protein Isoforms.
Nat Genet 2002 Jul;31(3):279-84
Slitrk protein, mouse
0
*Membrane Proteins
*Nerve Tissue Proteins
Protein Isoforms.
Mol Cell Neurosci 2003 Sep;24(1):117-29
SLC9A9 protein, human
0
*Sodium-Hydrogen Antiporter
Protein Isoforms.
J Med Genet 2003 Oct;40(10):733-40
NOXO1 protein, human
0
*Adaptor Proteins, Vesicular Transport
Protein Isoforms.
J Biol Chem 2003 Jul 4;278(27):25234-46
CTP phosphocholine cytidylyltransferase, beta isoform, mouse
EC 2.7.7.15
*Choline-Phosphate Cytidylyltransferase
Protein Isoforms.
Biochim Biophys Acta 2003 Jul 4;1633(1):1-12
Gle1 protein, human
0
*Nucleocytoplasmic Transport Proteins
Protein Isoforms.
J Cell Biol 2003 Mar 31;160(7):1029-40
SPTBN1 protein, human
0
*Spectrin
Protein Isoforms.
J Mol Neurosci 2001 Aug;17(1):59-70
CD44v9 antigen
0
*Antigens, CD44
Protein Isoforms.
Leukemia 2002 Jan;16(1):135-43
NCX10 protein, rat
0
*Sodium-Calcium Exchanger
Protein Isoforms.
Calcif Tissue Int 2000 Jul;67(1):60-7
myrmexins
0
*Ant Venoms
Protein Isoforms.
Toxicon 2000 Oct;38(10):1403-13
metallothionein isoform 1
0
*Metallothionein
Protein Isoforms.
Prostate 2000 May 1;43(2):125-35
Dido protein, mouse
0
*DNA-Binding Proteins
*Transcription Factors
Zinc Fingers
Protein Isoforms.
Proc Natl Acad Sci U S A 1999 Jul 6;96(14):7992-7
ataxin-
7
0
*Nerve Tissue Proteins
Spinocerebellar Degenerations
Protein Isoforms.
Nat Genet 1997 Sep;17(1):65-70
CRMP1 protein, human
0
*Nerve Tissue Proteins
Protein Isoforms.
Gene 1996 Nov 21;180(1-2):157-63
Nedd4 ubiquitin protein ligases
EC 6.3.2.19
*Ubiquitin-Protein Ligases
*Endosomal Sorting Complexes Required for Transport
Protein Isoforms.
EMBO J 1996 May 15;15(10):2371-80; Trends Biochem Sci. 2007 Dec;32(12):561-73
NFASC protein, human
0
*Nerve Growth Factors
*Cell Adhesion Molecules
Protein Isoforms.
Cell 1987;51(5):841