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Thymosin

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Definition: Thymosin. A family of heat-stable, polypeptide hormones secreted by the thymus gland. Their biological activities include lymphocytopoiesis, restoration of immunological competence and enhancement of expression of T-cell characteristics and function. They have therapeutic potential in patients having primary or secondary immunodeficiency diseases, cancer or diseases related to aging.  /biosyn /physiol permitted    Other names Thymosins; Thymosin Fs
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
thymosin beta-NB, human  0   *Thymosin. Ann N Y Acad Sci 2007 Sep;1112:286-96
thymosin beta15, rat  0   *Thymosin Protein Isoforms. Ann N Y Acad Sci 2007 Sep;1112:286-96
tetrathymosinbeta, C elegans  0   *Thymosin *Caenorhabditis elegans Proteins. Mol Biol Cell 2004 Oct;15(10):4735-48
(Met(0)6,Tyr(Me)12)deacetyl-thymosin beta4  0   Thymosin/*analogs & derivatives. Mediators Inflamm 2001 Apr;10(2):89-92
(Met(0)6,Phe(4F)12)deacetyl-thymosin beta4  0   Thymosin/*analogs & derivatives. Mediators Inflamm 2001 Apr;10(2):89-92
((n-nitroveratryl)oxy)chlorocarbamate-caged thymosin beta4  0   *Nitro Compounds Thymosin/*analogs & derivatives. J Cell Biol 2001 May 28;153(5):1035-48
thymosin beta(14)  0   *Thymosin. J Pept Sci 1997 Jul-Aug;3(4):282-90
thymosin beta(15), rat  0   *Thymosin. Nat Med 1996 Dec;2(12):1322-8
thymosin alpha(1) (24-28)  0   *Peptide Fragments *Thymosin. Biull Eksp Biol Med 1995 Jul;120(7):26-9
thymosin beta(4) sulfoxide  0   *Thymosin. Eur J Biochem 1995 Jun 1;230(2):650-7
thymosin beta(4) (11-19)  0   *Peptide Fragments *Thymosin. Neurochem Res 1994 Apr;19(4):451-6
deacetylthymosin beta(12)  0   *Thymosin. Biotechnol Ther 1993;4(3-4):221-37
thymosin beta(12)  140208-13-5   *Thymosin. Biochem J 1992 Apr 15;283( Pt 2):385-9
prothymosin alpha (1-30), Arg(30)  0   *Peptide Fragments *Protein Precursors Thymosin/*analogs & derivatives. Chem Pharm Bull (Tokyo) 1991;39(3):752
thymosin beta(9), methionine  0   *Thymosin. Chem Pharm Bull (Tokyo) 1990;38(8):2301
timoptin  120798-94-9   Thymosin/*analogs & derivatives Thymus Extracts. Izv Akad Nauk SSSR (Biol) 1990;(3):383
deacetylthymosin beta(4)(Xen)  125478-51-5   *Thymosin. Chem Pharm Bull (Tokyo) 1989;37(9):2467
deacetylthymosin beta(11)  120146-31-8   *Thymosin. Biotechnol Appl Biochem 1988;10(6):576
deacetylthymosin beta(7)  114732-68-2   *Thymosin. Chem Pharm Bull (Tokyo) 1988;36(2):700
thymosin fraction 7  0   Thymosin/*analogs & derivatives. Vopr Virusol 1988;33(1):34
deacetylthymosin beta(10)  109488-38-2   *Thymosin. Chem Pharm Bull (Tokyo) 1986;34(11):4708
Ptms protein, rat  0   *Proteins Phosphofructokinase-1/antagonists & inhibitors Thymosin. J Biol Chem 1986;261(13):5892
desacetylthymosin alpha(11)  102272-19-5   Thymosin/*analogs & derivatives. Chem Pharm Bull (Tokyo) 1985;33(12):5419
thymosin fraction 3  0   Thymosin/*analogs & derivatives. Biull Eksp Biol Med 1986;101(3):298
thymosin beta(1)  56574-49-3   *Ubiquitins Thymosin/*analogs & derivatives. Methods Enzymol 1985;116:233
deacetylthymosin beta(4)  0   *Thymosin. Chem Pharm Bull (Tokyo) 1984;32(11):4497
parathymosin alpha  95328-48-6   Thymosin/*analogs & derivatives. Proc Natl Acad Sci USA 1985;82(4):1050
thymosin beta(11)  92480-71-2 Thymosin beta11, 1-(3-mercapto-3-methylbutanoic acid)-2-L-leucine-, (SP-4-2)  *Thymosin. Arch Biochem Biophys 1984;233(2):815
thymosin alpha(7)  69772-65-2   Thymosin/*analogs & derivatives. Thymus 1984;6(1-2):27
thymosin beta(9)  81775-04-4   *Thymosin. Thymus 1984;6(1-2):27
prothymosin alpha  0   *Protein Precursors Thymosin/*analogs & derivatives. Proc Natl Acad Sci USA 1984;81(4):1008
thymosin alpha(11)  89072-27-5 Thymosin alpha1, 28a-glycine-28b-L-arginine-28c-L-glutamic acid-28d-L-alanine-28e-L-proline-28f-L-alanine-28g-L-asparagine  Thymosin/*analogs & derivatives. Proc Natl Acad Sci USA 1983;80(24):7424
thymosin beta(4)alanine  85410-66-8 Thymosin beta4, 1-(N-acetyl-L-alanine)  *Thymosin. Arch Biochem Biophys 1983;226(1):388
thymosin beta(10)arginine  88160-82-1 Thymosin beta4, 1-(N-acetyl-L-alanine)-7-glycine-10-L-alanine-11-L-serine-15-L-alanine-27-L-threonine-30-L-threonine-39-L-arginine-40-L-serine-41-L-glutamic acid-42-L-isoleucine  *Thymosin. Arch Biochem Biophys 1983;226(1):388
thymosin beta(10)  87397-91-9 Thymosin beta10  *Thymosin. Arch Biochem Biophys 1983;225(2):407
thymosin beta(8)  81775-03-3   *Thymosin. Chem Pharm Bull (Tokyo) 1983;31(4):1320
thymosin receptor  0   *Receptors, Immunologic Thymosin. Experientia 1982;38(5):618
thymosin fraction 5  0   Thymosin/*analogs & derivatives. Adv Pediatr 1981;28:229
thymosin beta(4)  77591-33-4 Thymosin beta4  *Thymosin Microfilament Proteins. J Biol Chem 1982;257(2):1000
desacetylthymosine alpha(1)  74221-77-5 Thymosin alpha1, N-deacetyl  Thymosin/*analogs & derivatives. Biochemistry 1980;19(14):3233; Biochemistry 1980;19(26):6096
thymalfasin  0   Thymosin/*analogs & derivatives.
Pharma Action Adjuvants, Immunologic ; Antineoplastic Agents 		Biochemistry 1980;19(14):3233

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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