encyclopedia of medical concepts
ψ 

Arylsulfotransferase

More information in Books or onNLM PubMed
Definition: A sulfotransferase that catalyzes the sulfation of a phenol in the presence of 3'-phosphoadenylylsulfate as sulfate donor to yield an aryl sulfate and adenosine 3',5'-bisphosphate. A number of aromatic compounds can act as acceptors; however, organic hydroxylamines are not substrates. Sulfate conjugation by this enzyme is a major pathway for the biotransformation of phenolic and catechol drugs as well as neurotransmitters. EC 2.8.2.1.      Other names Phenol Sulfotransferase; Sulphotransferase, Acetaminophen; Sulfotransferase, Phenol; Sulfotransferase, Flavonoid; Sulfotransferase, Dopamine; Sulfotransferase, Aryl; Sulfotransferase P, Phenol; Sulfotransferase M, Phenol; Sulfotransferase B, Catecholamine; Sulfotransferase A, Catecholamine; Sulfokinase; Phenolsulfotransferase P; Phenolsulfokinase; Phenol Sulfotransferase P; Phenol Sulfotransferase M; Phenol Sulfokinase; Flavonoid Sulfotransferase; Dopamine Sulfotransferase; Catecholamine Sulfotransferase B; Catecholamine Sulfotransferase A
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Phenol sulfotransferase deficiency  0   *Metabolism, Inborn Errors Arylsulfotransferase/deficiency.
Sult1a1 protein, mouse  EC 2.8.2.1   *Arylsulfotransferase.
SULT1A2 protein, human  EC 2.8.2.1   *Arylsulfotransferase.
Sult1c1 protein, mouse  EC 2.8.2.1   *Arylsulfotransferase.
SULT1 protein, zebrafish  EC 2.8.2.1   *Arylsulfotransferase *Zebrafish Proteins Protein Isoforms. Arch Biochem Biophys 2005 May 1;437(1):10-9
SULT1A1 protein, human  EC 2.8.2.1   *Arylsulfotransferase. Biochem J 1999 Jan 1;337(Pt 1):45-9; J Natl Cancer Inst. 2002 Nov 6;94(21):1635-40
arylsulfate sulfotransferase  EC 2.8.2.22   *Arylsulfotransferase. J Biochem (Tokyo) 1994 Jun;115(6):1097-100
2-naphthol sulfotransferase  EC 2.8.2.-   *Arylsulfotransferase. Comp Biochem Physiol (C) 1991;98(2-3):433

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify.
We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy