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HSP70 Heat-Shock Proteins

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Definition: A class of MOLECULAR CHAPERONES found in both prokaryotes and in several compartments of eukaryotic cells. These proteins can interact with polypeptides during a variety of assembly processes in such a way as to prevent the formation of nonfunctional structures.  coordinate with MITOCHONDRIAL PROTEINS or BACTERIAL PROTEINS if pertinent   
Examples HSC70 Heat-Shock Proteins; HSP72 Heat-Shock Proteins; HSP110 Heat-Shock Proteins 		Other names Heat-Shock Proteins, HSP70; Heat Shock Proteins 70; Heat Shock Protein 70; HSP70 Heat Shock Proteins; Heat-Shock Protein 70; Heat Shock 70 kDa Protein; Heat-Shock Proteins 70
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Hsp70Ba protein, Drosophila  0   *HSP70 Heat-Shock Proteins *Drosophila Proteins. PLoS One 2011;6(4):e17295
Hsp70-3 protein, rat  0   *HSP70 Heat-Shock Proteins. Biochim Biophys Acta 1998 Jan 7;1395(1):57-61
HSPA12B protein, rat  0   *HSP70 Heat-Shock Proteins. J Neurol Sci 2010 Jul 15;294(1-2):29-37
VER 155008  0   *Purine Nucleosides HSP70 Heat-Shock Proteins/antagonists & inhibitors. Cancer Chemother Pharmacol 2010 Aug;66(3):535-45
Hsp70B' protein, human  0   *HSP70 Heat-Shock Proteins. Cell Stress Chaperones 2008 Spring;13(1):105-10
Hsp70Ab protein, Drosophila  0   *HSP70 Heat-Shock Proteins *Drosophila Proteins. Cell Stress Chaperones 2008 Spring;13(1):11-7
Hsp70A protein, Drosophila  0   *HSP70 Heat-Shock Proteins *Drosophila Proteins. Cell Stress Chaperones 2008 Spring;13(1):11-7
HSPA1L protein, human  0   *HSP70 Heat-Shock Proteins. Neuropsychobiology. 2009;59(3):135-41
SSA2 protein, S cerevisiae  0   *HSP70 Heat-Shock Proteins *Saccharomyces cerevisiae Proteins.
SEP70 protein, human  0   *HSP70 Heat-Shock Proteins. Ann Otol Rhinol Laryngol 2006 Jan;115(1):47-58
HSPA1B protein, human  0   *HSP70 Heat-Shock Proteins.
Stch protein, rat  EC 3.6.1.-   *Adenosine Triphosphatases *HSP70 Heat-Shock Proteins Protein Subunits. EMBO J 1994 Mar 1;13(5):1216-25
HSPA12B protein, mouse  0   *HSP70 Heat-Shock Proteins. Proc Natl Acad Sci U S A 2003 Feb 4;100(3):1256-61
CHIP protein, zebrafish  EC 6.3.2.19   *Zebrafish Proteins *Ubiquitin-Protein Ligases HSP70 Heat-Shock Proteins. Biochemistry 2006 Apr 18;45(15):4749-59
heat shock 70-kDa protein 8 isoform 1, human  0   *HSP70 Heat-Shock Proteins *Protein Isoforms Stem Cells. Stem Cells 2005 Nov-Dec;23(10):1502-13
Hsp70.3 protein, mouse  0   *HSP70 Heat-Shock Proteins. Stroke 2004 Sep;35(9):2195-9
SSE1 protein, S cerevisiae  0   *HSP70 Heat-Shock Proteins *Saccharomyces cerevisiae Proteins.
SSB2 protein, S cerevisiae  EC 3.6.1.-   *Adenosine Triphosphatases *HSP70 Heat-Shock Proteins *Saccharomyces cerevisiae Proteins. Mol Cell Biol 2004 Oct;24(20);9186-97
HSPA9 protein, human  0   *HSP70 Heat-Shock Proteins *Mitochondrial Proteins.
HSPA7 protein, human  0   *HSP70 Heat-Shock Proteins.
HSP75 protein, sea urchin  0   *HSP70 Heat-Shock Proteins.
Osp94 protein, rat  0   *HSP70 Heat-Shock Proteins.
HSPA4L protein, human  0   *HSP70 Heat-Shock Proteins.
HSPA1A protein, human  0   *HSP70 Heat-Shock Proteins.
Hsp68 protein, Drosophila  0   *HSP70 Heat-Shock Proteins *Drosophila Proteins.
Hspa1b protein, rat  0   *HSP70 Heat-Shock Proteins.
Hspa2 protein, mouse  0   *HSP70 Heat-Shock Proteins.
Hst70 protein, rat  0   *HSP70 Heat-Shock Proteins. Biochim Biophys Acta 1990 Jan 30;1048(1):93-9
Stch protein, mouse  0   *HSP70 Heat-Shock Proteins.
heat shock protein 70L1, human  0   *HSP70 Heat-Shock Proteins. Blood 2004 Mar 1;103(5):1747-58
HSPA12B protein, human  0   *HSP70 Heat-Shock Proteins. Proc Natl Acad Sci U S A 2003 Feb 4;100(3):1256-61
HSPA12A protein, human  0   *HSP70 Heat-Shock Proteins. Proc Natl Acad Sci U S A 2003 Feb 4;100(3):1256-61
SSA4 protein, S cerevisiae  0   *HSP70 Heat-Shock Proteins *Saccharomyces cerevisiae Proteins. J Biol Chem 1990 Nov 5;265(31):18912-21
HSP70 protein, Mycobacterium tuberculosis  0   *Bacterial Proteins *HSP70 Heat-Shock Proteins. Immunity 2001 Dec;15(6):971-83
SSZ1 protein, S cerevisiae  0   *HSP70 Heat-Shock Proteins *Saccharomyces cerevisiae Proteins. FEBS Lett 2001 Nov 9;508(1):99-102; Mol Cell Biol 1998 Mar;18(3):1147-55
catecholamine-regulated protein, 40 kDa  0   *Nerve Tissue Proteins *HSP70 Heat-Shock Proteins Brain. J Neurochem 2001 Feb;76(4):1142-52
ECM10 protein, S cerevisiae  0   *HSP70 Heat-Shock Proteins *Saccharomyces cerevisiae Proteins. FEBS Lett 2000 Dec 29;487(2):307-12
Hsp71 protein, Coxiella burnetii  0   *Bacterial Proteins *HSP70 Heat-Shock Proteins. Infect Immun 1998 Dec;66(12):5882-8
SSQ1 protein, S cerevisiae  0   *HSP70 Heat-Shock Proteins *Mitochondrial Proteins *Saccharomyces cerevisiae Proteins. J Biol Chem 1998 Nov 20;273(47):31138-44
Hspa9b protein, mouse  0   *HSP70 Heat-Shock Proteins. Oncogene 1998 Aug 20;17(7):907-11
SglK protein, Myxococcus xanthus  0   *Bacterial Proteins *HSP70 Heat-Shock Proteins Myxococcus xanthus. J Bacteriol 1998 Oct;180(20):5357-68
GrpS protein, Myxococcus xanthus  0   *Bacterial Proteins *HSP70 Heat-Shock Proteins. J Bacteriol 1998 Oct;180(20):5357-68
hscC protein, E coli  0   *HSP70 Heat-Shock Proteins *Escherichia coli Proteins. Biochem Biophys Res Commun 1998 Sep 8;250(1):115-8
PSS1 protein, S pombe  0   *HSP70 Heat-Shock Proteins *Schizosaccharomyces pombe Proteins. Gene 1998 Mar 27;210(1):143-50
pp75 protein, rat  0   *Phosphoproteins *HSP70 Heat-Shock Proteins. J Biol Chem 1997 Jan 3;272(1):657-62
sks2 protein, S pombe  0   *HSP70 Heat-Shock Proteins *Schizosaccharomyces pombe Proteins. Gene 1996 Nov 28;181(1-2):45-9
DnaK3 protein, Synechococcus  0   *Bacterial Proteins *Membrane Proteins *HSP70 Heat-Shock Proteins. Biochem Biophys Res Commun 1994 Jun 15;201(2):848-54
HSP70B protein, Chlamydomonas  0   *Protozoan Proteins *HSP70 Heat-Shock Proteins. Plant Mol Biol 1996 Sep;31(6):1185-94
LHS1 protein, S cerevisiae  0   *HSP70 Heat-Shock Proteins *Saccharomyces cerevisiae Proteins. Mol Cell Biol 1996 Nov;16(11):6444-56
Hsp75 protein, rat  0   *HSP70 Heat-Shock Proteins. Mol Cell Biol 1996 Sep;16(9):4691-9
HSP91 protein, Arabidopsis  0   *HSP70 Heat-Shock Proteins *Arabidopsis Proteins. FEBS Lett 1996 Jul 15;390(1):113-8
Osp94 protein, mouse  0   *HSP70 Heat-Shock Proteins. J Biol Chem 1996 May 24;271(21):12327-32
glucose-regulated protein 170  0   *Glycoproteins *HSP70 Heat-Shock Proteins. FEBS Lett 1996 Feb 12;380(1-2):68-72
Hspa1a protein, rat  0   *HSP70 Heat-Shock Proteins. J Biol Chem 1995 Dec 15;270(50):29967-70
SSA1 protein, S cerevisiae  EC 3.6.1.3   *Adenosine Triphosphatases *HSP70 Heat-Shock Proteins *Saccharomyces cerevisiae Proteins. Mol Microbiol 1995 May;16(3):415-23
SSB1 protein, S cerevisiae  0   *HSP70 Heat-Shock Proteins *Saccharomyces cerevisiae Proteins. Biochem Biophys Res Commun 1995 Aug 15;213(2):484-9
protein p65, Beet yellows virus  0   *Viral Proteins *HSP70 Heat-Shock Proteins Closterovirus. Dokl Akad Nauk 1995 Jan;340(3):416-8
HSPA2 protein, human  0   *HSP70 Heat-Shock Proteins. Hum Mol Genet 1994 Oct;3(10):1819-22
HSPS-1 protein, Neurospora crassa  0   *Fungal Proteins *HSP70 Heat-Shock Proteins. J Bacteriol 1995 Jan;177(1):212-21
SSA3 protein, S cerevisiae  0   *HSP70 Heat-Shock Proteins *Saccharomyces cerevisiae Proteins. Yeast 1994 Aug;10(8):1093-100
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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