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Immunoglobulin G

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Definition: The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.  gammopathy: coordinate IMMUNOGLOBULIN G (IM) with PARAPROTEINEMIAS (IM) but consider also HYPERGAMMAGLOBULINEMIA, follow text   
Pharmacological Action Immunologic Factors
See Also Receptors, IgG
Examples Immunoglobulin gamma-Chains; Immunoglobulins, Intravenous; Long-Acting Thyroid Stimulator; Muromonab-CD3; Rho(D) Immune Globulin 		Other names IgG; Gamma Globulin, 7S; GT, Immunoglobulin; 7S Gamma Globulin; Polyglobin; Immunoglobulin GT; IgG4; IgG3; IgG2B; IgG2A; IgG2; IgG1; IgG(T); Allerglobuline
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
TuNEX protein  0   *Immunoglobulin G *Recombinant Fusion Proteins *Receptors, Tumor Necrosis Factor. J Chin Med Assoc. 2011 Dec;74(12):544-51.
asfotase alfa  0   *Alkaline Phosphatase *Immunoglobulin G *Recombinant Fusion Proteins Hypophosphatasia/drug therapy Enzyme Replacement Therapy. N Engl J Med. 2012 Mar 8;366(10):904-13
MEHD7945A  0   *Immunoglobulin G Antineoplastic Agents. Cancer Cell. 2011 Oct 18;20(4):472-86
Flt(1-3)-IgG  0   *Immunoglobulin G *Recombinant Fusion Proteins *Vascular Endothelial Growth Factor Receptor-1 Vascular Endothelial Growth Factor A/antagonists & inhibitors. Nat Med 1999 Jun;5(6):623-8
FP-1039  0   *Immunoglobulin G *Oncogene Proteins, Fusion *Receptor, Fibroblast Growth Factor, Type 1. Nat Rev Drug Discov. 2011 May;10(5):328
Hizentra  0   *Immunoglobulin G. Immunotherapy. 2011 Feb;3(2):163-76
rozrolimupab  0   *Immunoglobulin G *Recombinant Proteins. Curr Opin Mol Ther 2010 Dec;12(6):734-40
TRU 016  0   *Immunoglobulin G *Recombinant Fusion Proteins. Curr Opin Investig Drugs 2009 Dec;10(12):1383-90
ACE-011  0   *Recombinant Fusion Proteins Immunoglobulin G. J Bone Miner Res 2009 Apr;24(4):744-52
CD200-FC, mouse  0   *Immunoglobulin G. Arthritis Rheum. 2008 Apr;58(4):1038-43
TEM8-Fc  0   *Immunoglobulin G *Immunoglobulin Fc Fragments *Membrane Proteins. J Natl Cancer Inst 2007 Oct 17;99(20):1551-5
Boc protein, mouse  0   *Immunoglobulin G *Receptors, Cell Surface. Dev Cell 2006 May;10(5):647-56
Sdk2 protein, mouse  0   *Immunoglobulin G *Membrane Proteins. FASEB J. 2005 Apr;19(6):614-6
IgG D1.3  0   *Antibodies, Monoclonal *Immunoglobulin G.
sidekick-1 protein, mouse  0   *Immunoglobulin G *Membrane Proteins. J Am Soc Nephrol 2004 Jul;15(7):1721-30
antiegressin, Trypanosoma cruzi  0   *Immunoglobulin G. J Parasitol. 2004 Feb;90(1):85-91
anti-U-like antibody, human  0   *Autoantibodies *Immunoglobulin G. Vox Sang 2002 Jul;83(1):51-4
BOC protein, human  0   *Immunoglobulin G *Receptors, Cell Surface. Mol Carcinog 2003 May;37(1):1-4
malmo protocol  0   *Cyclophosphamide *Factor IX *Factor VII *Factor VIII *Immunoglobulin G Drug Combinations. Haematologica 2000 Oct;85(10 Suppl):48-50
3F8 antibody  0   *Antibodies, Monoclonal *Immunoglobulin G Antibodies. Med Pediatr Oncol 2000 Dec;35(6):656-8
indium 111-cT84.66 monoclonal antibody  0   *Antibodies, Monoclonal *Immunoglobulin G Indium Radioisotopes. J Nucl Med 1998 Dec;39(12):2097-104
L49-sFv-beta-lactamase  EC 3.5.2.-   *beta-Lactamases *Immunoglobulin G Recombinant Fusion Proteins. Bioconjug Chem 1997 Jul-Aug;8(4):510-9
LILRB4 protein, human  0   *Receptors, Cell Surface Immunoglobulin G. J Exp Med 1997 May 19;185(10):1743-51; J Immunol 1997 Sep 1;159(5):2342-9
TNFR-Fc fusion protein  185243-69-0   *Immunoglobulin G *Receptors, Tumor Necrosis Factor Arthritis, Rheumatoid Recombinant Fusion Proteins Tumor Necrosis Factor-alpha.
Pharma Action Anti-Inflammatory Agents, Non-Steroidal ; Gastrointestinal Agents ; Immunologic Factors ; Immunosuppressive Agents ; Antirheumatic Agents 		J Immunol 1995 Nov 15;155(10):5038-45ENBREL
technetium Tc 99m hydrazinonicotinate-IgG  0   *Immunoglobulin G *Organotechnetium Compounds. Eur J Nucl Med 1996 Apr;23(4):414-21
daclizumab  152923-56-3 Immunoglobulin G 1, (human-mouse monoclonal 1H4 gamma-chain, anti-human interleukin 2 receptor), disulfide with human-mouse monoclonal clone 1H4 light chain, dimer  *Immunoglobulin G *Antibodies, Monoclonal, Humanized.
Pharma Action Immunosuppressive Agents 		Clin Pharmacol Ther 1995 Sep;58(3):363-4ZENAPAX
limbic system-associated membrane protein  0   *Cell Adhesion Molecules, Neuronal GPI-Linked Proteins Immunoglobulin G. Neuron 1995 Aug;15(2):287-97
polyacrylic-IgG polymer  0   *Acrylic Resins *Immunoglobulin G Complement Activation. J Biomater Sci Polym Ed 1994;6(1):67-78
immunoglobulin G (285-292)  160699-86-5   *Immunoglobulin G *Immunoglobulin Fragments. Bioorg Khim 1994 Jun;20(6):617-26
immunocorticotropin  150035-99-7 L-Valine, N-(N2-(N-(N-(N-(N-(1-(N2-(N2-L-valyl-L-lysyl)-L-lysyl)-L-prolyl)glycyl)-L-seryl)-L-seryl)-L-valyl)-L-lysyl)  *Immunoglobulin G *Peptide Fragments Adrenocorticotropic Hormone Immunoglobulin Variable Region Immunoglobulin Heavy Chains. Int J Pept Protein Res 1993 Jun;41(6):517-21
technetium TC 99m polyclonal IgG  0   *Immunoglobulin G *Organotechnetium Compounds. Nucl Med Commun 1993 Jan;14(1):64-9
immunoglobulin A, immunoglobulin G, immunoglobulin M drug combination  0   *Immunoglobulin A *Immunoglobulin G *Immunoglobulin M Drug Combinations. Przeglad Epidemiol 1991;45(4):273-7
Avid AL gel  0   *Pyridines Sepharose/*analogs & derivatives Gels Immunoglobulin G Ligands. J Chromatogr 1992 Apr 24;597(1-2):101-9
technetium Tc 99m thiol reduction-mediated IgG  0   *Immunoglobulin G *Organotechnetium Compounds. Am J Physiol Imaging 1991 Oct-Dec;6(4):176-82
DTPA-IgG complex  0   *Immunoglobulin G Pentetic Acid/*analogs & derivatives Indium Radioisotopes. Nucl Med Commun 1991;12(3):175
IgG hinge protein-gastrin 17 (2-17)  0   *Gastrins *Immunoglobulin G *Peptide Fragments Vaccines, Conjugate. Int J Pept Protein Res 1991;37(2):90
gastrin 34 (1-14)-IgG hinge protein-gastrin 17 (2-17)  133515-75-0   *Gastrins *Immunoglobulin G *Peptide Fragments Vaccines, Conjugate. Int J Pept Protein Res 1991;37(2):90
bleomycin-immunoglobulin G conjugate  0   *Immunoglobulin G Bleomycin/*analogs & derivatives. Arch Biochem Biophys 1990;283(2):519
agalactosyl IGG  0   *Immunoglobulin G. Gut 1990;31(4):431
CD4-IgG1 hinge fusion protein, recombinant  0   *Immunoglobulin gamma-Chains *Recombinant Fusion Proteins *Antigens, CD4 Immunoglobulin G. Arch Virol 1990;111(1-2):29
gadolinium-IGG complex  0   *Immunoglobulin G Gadolinium. Magn Reson Med 1988;8(2):180
alergim PG  0   *Immunoglobulin G Allergens Biological Agents Pollen. Rev Ig (Bacteriol) 1988;33(1):29
immunoglobulin G-dextran conjugate  0   *Dextrans *Immunoglobulin G. Biull Eksp Biol Med 1988;106(7):78
allergam  0   *Immune Sera Immunoglobulin E Immunoglobulin G. Rev Fr Transfus Immunohematol 1986;29(5):347
antineoplastic agent K 18  0   Melphalan Immunoglobulin G. Nippon Gan Chiryo Gakkai Shi 1986;21(9):89
IGG-horseradish peroxidase  0   *Horseradish Peroxidase *Immunoglobulin G. Biol Reprod 1986;35(4):1045
anti-IgG  0   *Antibodies, Anti-Idiotypic Immunoglobulin G. Eur J Immunol 1986;16(7):871
glycosylated IgG  0   *Immunoglobulin G Glycosylation. Biol Chem Hoppe Seyler 1985;366(4):361
mitomycin C-immunoglobulin M antibody conjugate  0   *Antibodies, Monoclonal *Mitomycin Immunotoxins Immunoglobulin G. J Appl Biochem 1984;6(5-6):297
2,4-dinitrophenyl-IgG  0   *Dinitrobenzenes *Immunoglobulin G. Cell Immunol 1985;91(2):362
threonyl-lysyl-proline  41961-56-2   *Oligopeptides Immunoglobulin G Immunoglobulin Fragments. Int J Immunopharmacol 1985;7(1):73
polymeric IgG  0   *Immunoglobulin G Polymers. Clin Nephrol 1984;22 (5):244
Globin-N  0   *Immunoglobulin A *Immunoglobulin G Epilepsy/drug therapy. Yakubutsu Seishin Kodo 1984;4(2):6163
antilipopolysaccharide antibodies  0   *Immunoglobulins Immunoglobulin G. S Afr Med J 1984;66(18):674
immunoglobulin Facb fragment  0   *Immunoglobulin G *Immunoglobulin Fab Fragments *Immunoglobulin Fc Fragments. Immunology 1984;52(1):17
IgG Fc-binding protein, Streptococcus  0   *Bacterial Proteins Antigens, Bacterial Immunoglobulin G Streptococcus Receptors, IgG. Int Arch Allergy Appl Immunol 1982;67(4):369
Hepaga  0   *Hepatitis B Antibodies *Immunoglobulin G Hepatitis B Surface Antigens. Cas Lek Ces 1982;121(4):105
myeloma protein Dob  0   *Immunoglobulin G *Myeloma Proteins. Biochemistry 18(19):4054;1979; Biochemistry 18(19):4068;1979
IgG, sulfonated  0   *Immunoglobulin G. Vox Sang 37(1):14;1979
ablastin  0   *Immunoglobulin G. Aust J Exp Biol Med Sci 56(6):741;1978
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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