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Dextrans

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Definition: A group of glucose polymers made by certain bacteria. Dextrans are used therapeutically as plasma volume expanders and anticoagulants. They are also commonly used in biological experimentation and in industry for a wide variety of purposes.     
Pharmacological Action Anticoagulants; Plasma Substitutes 		Other names Dextran T 500; Dextran T 40; Dextran B 1355 S; Dextran B 1355; Saviosol; Rheopolyglucin; Rheomacrodex; Rondex; Rheoisodex; Rheodextran; Promit; Polyglucin; Macrodex; Infukoll; Hyskon; Hemodex; Dextran T-500; Dextran T-40; Dextran T 70; Dextran M 70
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Polyglucinum  0   *Dextrans. Zh Mikrobiol Epidemiol Immunobiol. 2011 May-Jun;(3):57-61
dextran-flufenamic acid ester  0   *Dextrans Flufenamic Acid/*analogs & derivatives. J Drug Target 2011 Jun;19(5):336-43
dextran-graft-polybutylmethacrylate  0   *Acrylic Resins *Dextrans. Acta Biomater 2010 Sep;6(9):3506-13
naproxen dextran ester  0   *Dextrans Naproxen/*analogs & derivatives. J Colloid Interface Sci 2009 Oct 1;338(1):56-62
dextran ibuprofen ester  0   *Dextrans Ibuprofen/*analogs & derivatives. J Colloid Interface Sci 2009 Oct 1;338(1):56-62
diethylaminoethyl-dextran-methyl methacrylate graft copolymer  0   *Dextrans *Methylmethacrylates. Molecules 2009;14(7):2669-83
dextran-block-poly(-benzyl L-glutamate) copolymer  0   *Dextrans Polyglutamic Acid/*analogs & derivatives. Angew Chem Int Ed Engl. 2009;48(14):2572-5
dextran tetramethylrhodamine  0   *Dextrans *Rhodamines. Graefes Arch Clin Exp Ophthalmol 2008 Nov;246(11):1553-8
dextran methacylate phthalate  0   *Dextrans *Methacrylates Phthalic Acids. J Drug Target 2008 Nov;16(9):649-59
dextran-co-poly(methyl methacrylate)  0   *Dextrans *Polymethyl Methacrylate. Biomacromolecules 2008 Nov;9(11):3033-8
2-(pyridinyldithio)ethylcarbamoyl dextran  0   *Dextrans *Disulfides. Colloids Surf B Biointerfaces 2008 Jan 15;61(1):113-7
poly(N-isopropylacrylamide)-dextran-maleic acid  0   *Dextrans *Maleates Polymers. J Biomater Sci Polym Ed 2007;18(7):901-24
polylysine-graft-poly(N(epsilon)-amidinolysine)-graft-dextran  0   *Dextrans *Polylysine. Nucleic Acids Symp Ser (Oxf) 2005;(49):329-30
AZ 10992  0   *Dextrans Paclitaxel/*analogs & derivatives. J Control Release 2007 Jan 22;117(1):40-50
fluorouracil-acetic-acid-dextran conjugate  0   *Dextrans Fluorouracil/*analogs & derivatives. Drug Dev Ind Pharm 2006 Jul;32(6):757-63
methacrylated dextran  0   *Dextrans *Methacrylates. Biomaterials. 2006 Oct;27(30):5277-85
fluoro-emerald  0   *Dextrans *Fluoresceins. J Neurosci Methods. 2006 Jul 15;155(1):20-7
APTS-dextran  0   *Dextrans *Pyrenes. Pharm Res. 2006 Jul;23(7):1491-501
amphotericin B-dextran imine conjugate  0   *Dextrans Amphotericin B/*analogs & derivatives. Biomacromolecules 2006 May;7(5):1529-35
methotrexate-GIVGPL-dextran  0   *Dextrans *Methotrexate *Oligopeptides. J Pharm Sci 2006 Mar;95(3):542-51
methotrexate-PVGLIG-dextran  0   *Dextrans *Methotrexate *Oligopeptides. J Pharm Sci 2006 Mar;95(3):542-51
Cy5.5-DTPA-galactosyl-dextran  0   *Carbocyanines *Dextrans *Pentetic Acid Fluorescent Dyes. Nucl Med Biol 2005 Oct;32(7):687-93
dextran hydroxyethyl methacrylate  0   *Dextrans *Methacrylates. Biomacromolecules 2006 Jan;7(1):373-9
NASHA-Dx copolymer  0   *Dextrans Hyaluronic Acid/*analogs & derivatives. Urology 2004 Aug;64(2):276-81
dextranomer-hyaluronic acid copolymer  0   *Dextrans *Hyaluronic Acid. J Urol 2004 Jun;171(6 Pt 1):2413-6
carboxymethyldextran-thiomannopyranoside-pyrimethamine  0   *Dextrans Pyrimethamine/*analogs & derivatives. J Pharm Sci 2003 Oct;92(10):2109-16
succinyldextranthiomannopyranoside-pyrimethamine  0   *Dextrans Pyrimethamine/*analogs & derivatives. J Pharm Sci 2003 Oct;92(10):2109-16
dexamethasone succinate dextran  0   *Dextrans Dexamethasone/*analogs & derivatives. Yao Xue Xue Bao 2001 Aug;36(8):625-30
phenylacetate carboxymethyl benzylamide dextran  0   *Dextrans. Br J Cancer 2003 Jun 16;88(12):1987-94
RG1192  0   *Dextrans. J Biomed Mater Res 2002 Oct;62(1):46-55
dextranmethylcarboxylate benzylamide sulfate  0   *Benzyl Compounds *Dextrans. Carbohydr Res 2001 May 8;332(1):75-83
2,2,6,6-tetramethylpiperidine-1-oxyldextran  0   *Dextrans. Biosci Biotechnol Biochem 2001 Apr;65(4):787-94
technetium-diethylenetriaminepentaacetic acid-mannosyl-dextran  0   *Dextrans *Pentetic Acid *Mannans *Organotechnetium Compounds. J Nucl Med 2001 Jun;42(6):951-9
dextran-polylactide hydrogel  0   *Dextrans *Polyesters Hydrogels. J Biomed Mater Res 2001 Jan;54(1):1-11
DCM-Dex-CDDP  0   *Cisplatin *Dextrans. Anticancer Drugs 2000 Jan;11(1):33-8
T 0128  0   *Dextrans Topotecan/*analogs & derivatives. Cancer Res 2000 Jun 1;60(11):2988-95
P604 polymer  0   *Dextrans. Invest Radiol 1999 Nov;34(11):663-8
DiHA dextran copolymer  0   *Dextrans. Acta Obstet Gynecol Scand 1999 May;78(5):436-42
epidermal growth factor--dextran-tyrosine conjugate  0   *Dextrans *Epidermal Growth Factor Drug Carriers. Int J Mol Med 1998 Apr;1(4):693-702
dextran-5-aminosalicylic acid  0   *Aminosalicylic Acids *Dextrans. Arch Pharm Res 1998 Apr;21(2):179-86
1-(N-(3-aminopropyl)-N-(3-ammoniopropyl)amino)diazen-1-ium-1,2-diolate-dextran  0   *Azetidines *Dextrans. J Controlled Release 1998 Feb 12;51(2-3):153-9
(4,5-dimethoxy-2-nitrobenzyl)fluorescein dextran  0   *Dextrans *Fluoresceins. Biophys J 1998 Jun;74(6):3302-12
poly(lysine)-graft-dextran  0   *Dextrans Polylysine/*analogs & derivatives. Nucleic Acids Symp Ser 1997;(37):225-6
FK 506-dextran conjugate  0   *Dextrans *Tacrolimus. Transplant Proc 1998 Jun;30(4):1029-30
hypertonic saline-dextran solution  0   *Dextrans *Sodium Chloride Saline Solution, Hypertonic. Am J Vet Res 1996 Jan;57(1):97-104
RGTA11  0   *Dextrans. J Biomed Mater Res 1996 Jul;31(3):293-7
RGT 11  0   *Dextrans. Int J Biol Macromol 1996 Feb;18(1-2):141-5
CMDBS 25  171235-75-9   *Dextrans. Transplant Proc 1996 Apr;28(2):593-4
ferumoxtran-10  0   *Dextrans *Magnetite Nanoparticles.
Pharma Action Contrast Media 		Magn Reson Imaging 1995;13(5):661-74
hemoglobin-dextran 10-benzene-tetracarboxylate  0   *Dextrans *Hemoglobins Blood Substitutes. Ann Pharm Fr 1995;53(3):111-8
N-ethyl-3-(2-pyridyldisulfanyl)propionamide dextran  0   *Dextrans *Pyridines. J Chromatogr B Biomed Appl 1995 Apr 7;666(1):21-31
deflux  0   *Dextrans *Hyaluronic Acid Prostheses and Implants. J Urol 1995 Aug;154(2 Pt 2):800-3
Cl-NERF-dextran  0   *Dextrans *Fluoresceins. J Membr Biol 1995 Mar;144(1):21-30
(6-methoxy-N-(4-aminobutyl)quinolinium bromide)-dextran  0   *Dextrans *Quinolinium Compounds. J Membr Biol 1995 Mar;144(1):21-30
carboxydextran-coated magnetic iron oxide particles  0   *Iron *Oxides Dextrans. Invest Radiol 1995 Feb;30(2):98-103
NuCa Green  0   *Dextrans Calcium. Exp Cell Res 1995 May;218(1):166-73
dextran-(1,6-bis(2-hydroxypropyl-1-amino)hexane)-dextran  0   *Dextrans *Propanolamines. J Biomater Sci Polym Ed 1994;6(6):549-64
dextranox-methyl polyethylene glycol  0   *Dextrans *Polyethylene Glycols. Pharm Res 1994 Nov;11(11):1588-92
dextran carbazate  0   *Dextrans *Hydrazines. Ann N Y Acad Sci 1994 Nov 30;745:297-320
dextran benzenehexacarboxylate  148374-18-9   *Benzoates *Dextrans. J Protein Chem 1994 Jan;13(1):1-8
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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