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| Arthritis, Rheumatoid |
| A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| in children = ARTHRITIS, JUVENILE RHEUMATOID; includes PCE: polyarthrite chronique +¬volutive; tends to be chronic so do not coord with CHRONIC DISEASE
| Other names Rheumatoid Arthritis; Rheumatoid Arthritis
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| Substance | CAS Registry & name | Categories | Source
|
| infliximab
| 0
|
*Antibodies, Monoclonal Arthritis, Rheumatoid Crohn Disease Tumor Necrosis Factor-alpha.
Pharma Action Antirheumatic Agents ; Anti-Inflammatory Agents ; Dermatologic Agents ; Gastrointestinal Agents
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N Engl J Med 1997 Oct 9;337(15):1029-35 | REMICADE
| rituximab
| 0
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*Antibodies, Monoclonal Arthritis, Rheumatoid Lymphoma, B-Cell.
Pharma Action Antineoplastic Agents ; Immunologic Factors ; Antirheumatic Agents
|
Oncology (Huntingt) 1994 Dec;8(12):84, 87 | RITUXAN
| abatacept
| 0
|
Arthritis, Rheumatoid Tumor Necrosis Factor-alpha *Immunoconjugates.
Pharma Action Immunosuppressive Agents ; Antirheumatic Agents
|
Nat Immunol 2002 Nov;3(11):1056-7 | ORENCIA
TNFR-Fc fusion protein
| 185243-69-0
|
*Immunoglobulin G *Receptors, Tumor Necrosis Factor Arthritis, Rheumatoid Recombinant Fusion Proteins Tumor Necrosis Factor-alpha.
Pharma Action Anti-Inflammatory Agents, Non-Steroidal ; Gastrointestinal Agents ; Immunosuppressive Agents ; Biological Response Modifiers ; Antirheumatic Agents
|
J Immunol 1995 Nov 15;155(10):5038-45 | ENBREL
| adalimumab
| 0
|
Arthritis, Rheumatoid Tumor Necrosis Factor-alpha *Antibodies, Monoclonal.
Pharma Action Antirheumatic Agents
|
Ann Rheum Dis 2002 Apr;61(4):311-8 | HUMIRA
OM-8930
| 81207-56-9
OM 8930
|
Escherichia coli Adjuvants, Immunologic Arthritis, Rheumatoid/drug therapy.
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Z Rheumatol 1981;40(5):228
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| RHP protein, human
| 0
|
*Blood Proteins Antibodies Arthritis, Rheumatoid Complement Activating Enzymes Biological Markers.
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Biochem Biophys Res Commun 1985;128(3):1288
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