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Delayed-Action Preparations

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Definition: Dosage forms of a drug that act over a period of time by controlled-release processes or technology.  IM general only; coord with specific drug   
Examples Drug Implants; Tablets, Enteric-Coated 		Other names Timed-Release Preparations; Sustained-Release Preparations; Prolonged-Action Preparations; Depot Preparations; Timed-Release Preparation; Timed Release Preparations; Sustained-Release Preparation; Prolonged-Action Preparation; Preparations, Controlled-Release; Preparation, Controlled-Release; Depot Preparation; Delayed-Action Preparation; Delayed Action Preparations; Controlled-Release Preparation; Controlled Release Preparations; Controlled-Release Preparations
Substances having this pharmacologic action: carbetocin; aspirin, magnesium oxide combination; methoxyethylene-maleic anhydride copolymer
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
oxycodone naloxone combination  0   *Naloxone *Oxycodone Drug Combinations Constipation/prevention & control Delayed-Action Preparations. Drug Ther Bull. 2010 Dec;48(12):138-41
luprolide acetate gel depot  0   *Leuprolide Delayed-Action Preparations Antineoplastic Agents, Hormonal. Urology. 2003 Feb;61(2 Suppl 1):25-31ELIGARD
poly(trimellitylimidoglycine-co-sebacic anhydride)-b-polyethylene glycol  0   *Anhydrides *Polyethylene Glycols Delayed-Action Preparations Drug Carriers. Int J Pharm 2000 Jan 20;194(1):51-60
poly(sebacic anhydride)-b-polyethylene glycol  0   *Anhydrides *Polyethylene Glycols Delayed-Action Preparations Drug Carriers. Int J Pharm 2000 Jan 20;194(1):51-60
polirem  0   Rimantadine/*analogs & derivatives Tablets Delayed-Action Preparations. Voen Med Zh 1995 Feb;(2):48-9
indometafen  0   Tamoxifen/*analogs & derivatives Delayed-Action Preparations. Patol Fiziol Eksp Ter 1994 Jul-Sep;(3):20-2
stearic-sebacic acid polyanhydride copolymer  0   *Polymers *Decanoic Acids *Stearic Acids Delayed-Action Preparations Drug Carriers. J Biomater Sci Polym Ed 1994;6(3):297-311
SC 53450  0   *Butadienes *Polymers *Misoprostol Delayed-Action Preparations. J Pharmacol Exp Ther 1994 Apr;269(1):151-6
Phycon 6600  0   *Silicone Gels Delayed-Action Preparations. Drug Des Deliv 1989;4(3):237
karotolin  84013-95-6   *Carotenoids *Fatty Acids, Unsaturated *Vitamin E Drug Combinations Delayed-Action Preparations. Stomatologiia (Mosk) 1990;69(2):25
polyvinyl alcohol hydrogel  0   *Polyvinyl Alcohol Delayed-Action Preparations Excipients Hydrogels. Chem Pharm Bull (Tokyo) 1989;37(9):2491
Sch 434  132316-36-0   *Loratadine *Pseudoephedrine Drug Combinations Delayed-Action Preparations. J Allergy Clin Immunol 1989;83(6):1083CLARITIN-D; CLARITIN-D 24 HOUR; LORATADINE AND PSEUDOEPHEDRINE SULFATE
poly(2-vinylpyridine)  25014-15-7   *Polyvinyls Delayed-Action Preparations. Biomaterials 1988;9(5):424
moexipril  103775-10-6   *Tetrahydroisoquinolines Delayed-Action Preparations.
Pharma Action Angiotensin-Converting Enzyme Inhibitors 		Proc West Pharmacol Soc 1988;31:87UNIVASC; MOEXIPRIL HYDROCHLORIDE
5-fluorouracil-polysiloxane condensate  0   *Fluorouracil *Siloxanes Delayed-Action Preparations. Chung Hua Chung Liu Tsa Chih 1987;9(6):415
norethisterone cholesterol  0   *Cholesterol *Norethindrone Drug Combinations Delayed-Action Preparations. Contraception 1988;37(4):349
decanedioic acid-4,4'-(1,3-propanediylbis(oxy))bis(benzoic acid) copolymer  90409-78-2   *Decanoic Acids *Polyesters Delayed-Action Preparations Drug Carriers.
Pharma Action Biocompatible Materials 		J Pediatr Surg 1988;23(1 Pt 2):3GLIADEL
cellulose, hydrogen phthalate  9004-44-8   Cellulose/*analogs & derivatives Delayed-Action Preparations. Pharm Acta Helv 1987;62(9):255
iron(II)-ascorbic acid complex  0   *Ascorbic Acid *Ferrous Compounds Delayed-Action Preparations.
Pharma Action Antineoplastic Agents 		Anticancer Res 1986;6(5):1033
procaine acryloyl polymer  57635-62-8   *Acrylic Resins Procaine/*analogs & derivatives Delayed-Action Preparations. Eur J Pharmacol 1985;114(3):253
procainamide acryloyl polymer  57635-65-1   *Acrylic Resins Procainamide/*analogs & derivatives Delayed-Action Preparations. Eur J Pharmacol 1985;114(3):253
deriphyllin-digoxin  0   *Digoxin Drug Combinations Theophylline/*analogs & derivatives Delayed-Action Preparations. Int J Clin Pharmacol Ther Toxicol 1986;24(1):30
bambuterol  81732-65-2   Terbutaline/*analogs & derivatives Delayed-Action Preparations Prodrugs.
Pharma Action Bronchodilator Agents 		Eur J Clin Pharmacol 1985;29(4):425
stearyl tyrosine  73393-27-8   Tyrosine/*analogs & derivatives Delayed-Action Preparations. J Biol Stand 1985;13(1):43
pegaspargase  0   *Asparaginase *Polyethylene Glycols Delayed-Action Preparations Enzymes, Immobilized.
Pharma Action Antineoplastic Agents 		Cancer Biochem Biophys 1984;7(2):175ONCASPAR
barium selenate  7787-41-9   *Barium Compounds *Selenium Compounds Delayed-Action Preparations. Vet Rec 1984;114(23):565
BY 118K  0   *Theophylline Delayed-Action Preparations. Prax Klin Pneumol 1984;38(5):182
impletol depot Bayer  95017-34-8 Benzoic acid, 4-amino-, 2-(diethylamino)ethyl ester, mixt. with 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione and 1-ethenyl-2-pyrrolidinone homopolymer  *Caffeine *Povidone *Procaine Drug Combinations Delayed-Action Preparations. Reumatologia 1983;21(2):167
nitrisken retard  66848-46-2   *Isosorbide Dinitrate *Pindolol Drug Combinations Delayed-Action Preparations. Med Welt 1983;34(33-34):906
streptobicillin depot  85160-58-3 D-Streptamine, O-2-deoxy-2- (methylamino)-alpha-L-glucopyranosyl-(1-2)-O-5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl-(1-4)-N,N'-bis(aminoiminomethyl)-, sulfate (2:3) (salt), mixt. with N,N'-bis(phenylmethyl)-1,2-ethanediamine bis((2S-(2alpha,5alpha,6beta))  *Penicillin G Benzathine *Streptomycin *Vitamin A Drug Combinations Delayed-Action Preparations. Vet Med Nauki 1982;19(5):85
Testoviron-depot  54175-25-6   *Testosterone Drug Combinations Delayed-Action Preparations. Clin Endocrinol Metab 1982;11(3):625
Diumide-K continus  84788-22-7 Benzoic acid, 5-(aminosulfonyl)-4-chloro-2-((2-furanylmethyl)amino)-, compd. with potassium chloride (KCl) (1:1)  *Furosemide *Potassium Chloride Drug Combinations Delayed-Action Preparations. J Int Med Res 1982;10(5):357
ACTH amide (1-18), Gly(1)  0   *Peptide Fragments Adrenocorticotropic Hormone/*analogs & derivatives Delayed-Action Preparations. J Pharm Pharmacol 1982;34(5):342
sulfalene meglumine  56782-29-7 D-Glucitol, 1-deoxy-1-(methylamino)-, compd. with 4-amino-N-(6-methoxy-3-pyridazinyl)benzenesulfonamide (1:1)  Sulfalene/*analogs & derivatives Delayed-Action Preparations. Ter Arkh 1981;53(4):108
insulin, (B1)-des-Phe  51798-72-2 Insulin, 1B-de-L-phenylalanine  Insulin/*analogs & derivatives Delayed-Action Preparations. Med Klin 1981;76(11):319
isosorbide-5-mononitrate  16051-77-7   Isosorbide Dinitrate/*analogs & derivatives Delayed-Action Preparations.
Pharma Action Vasodilator Agents ; Nitric Oxide Donors 		Med Welt 1981;32(14A):479ISOSORBIDE MONONITRATE; ISMO; MONOKET; IMDUR
safapryn  51900-85-7   *Acetaminophen *Aspirin Drug Combinations Delayed-Action Preparations. Lancet 1981;1(8223):777
Trasidrex  71265-68-4 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-, 1,1-dioxide, mixt. with 1-((1-methylethyl)amino)-3-(2-(2-propenyloxy)phenoxy)-2-propanol hydrochloride  *Cyclopenthiazide *Oxprenolol Drug Combinations Delayed-Action Preparations. Br J Clin Pract 1980;34(3):140
Insulin, Ultratard  0   *Insulin Delayed-Action Preparations. Q J Med 1979;48(191):493
deriphyllin  32156-80-2 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, compd. with 2,2'-iminobis(ethanol) (1:1)  Theophylline/*analogs & derivatives Delayed-Action Preparations. Int J Clin Pharmacol Biopharm 17(9):394;1979
ferrous sulfate  7720-78-7 sulfuric acid, iron(2+) salt (1:1)  *Ferrous Compounds Delayed-Action Preparations Hematinics Reactive Oxygen Species Anemia, Iron-Deficiency. Acta Paediatr Scand 1979;68(5):705; Arch Environ Health 1979;34(6):424; Chem Biol Interact 26(2):121;1979; Ginekol Pol 46(5):573;1975; Pol Tyg Lek 32(26):1017;1977; Ther Hung 1979;27(4):169; Ther Hung 24(1):33;1976FOLVRON
17-alpha-hydroxy-progesterone caproate  630-56-8 17-((1-oxohexyl)oxy)pregn-4-ene-3,20-dione  *Hydroxyprogesterones Antineoplastic Agents Delayed-Action Preparations Progesterone Congeners.
Pharma Action Estradiol Antagonists ; Progestins 		Endokrinologie 73(1):33;1979; Ther Umsch 36(6):516;1979; Vopr Onkol 1979;25(10):53DELALUTIN; HYDROXYPROGESTERONE CAPROATE; MAKENA
Tryptal  57773-65-6 Luteinizing hormone-releasing factor, 6-D-tryptophan-9-(N-ethyl-L-prolinamide)-10-deglycinamide  Triptorelin Pamoate/*analogs & derivatives Delayed-Action Preparations. Am J Obstet Gynecol 1979;135(6):755; Am J Obstet Gynecol 1979;135(6):759; Arch Sex Behav 1980;9(5):441; Endocrinology 103(6):2299;1978; Endocrinology 1979;105(5):1191; J Clin Endocrinol Metab 1980;50(1):179; Life Sci 1979;25(12):1065
Piloplex  62783-28-2 2-Propenoic acid, 2-methyl-, dodecyl ester, polymer with 2-propenoic acid, compd. with (3S-cis)-3-ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-2(3H)-furanone  *Pilocarpine Delayed-Action Preparations Ophthalmic Solutions. Br J Ophthalmol 63(1):45;1979
insulin, depot  0   Insulin/*analogs & derivatives Delayed-Action Preparations. Nephron 22(4-6):460;1978
betamethasone acetate phosphate  52081-45-5   Betamethasone/*analogs & derivatives Delayed-Action Preparations.
Pharma Action Bronchodilator Agents 		Rev Med Chil 106(9):699;1978CELESTONE SOLUSPAN; BETAMETHASONE ACETATE AND BETAMETHASONE SODIUM PHOSPHATE
Plexafer F  66771-90-2   *Ferrous Compounds *Folic Acid Drug Combinations Delayed-Action Preparations. J Int Med Res 6(1):34;1978
testosterone 17 beta-cypionate  58-20-8 Androst-4-en-3-one, 17-(3-cyclopentyl-1-oxopropoxy)-, (17-beta)  Testosterone/*analogs & derivatives Delayed-Action Preparations.
Pharma Action Androgens ; Anabolic Agents 		Br Heart J 39(11):1217;1977; Fertil Steril 1980 33(2):201DEPO-TESTOSTERONE; TESTOSTERONE CYPIONATE
caprovestrol  75919-66-3 Caprovestrol  *Estradiol *Hydroxyprogesterones Drug Combinations Delayed-Action Preparations. Vopr Okhr Materin Det 21(5):72;1976
fluphenazine depot  5002-47-1   Fluphenazine/*analogs & derivatives Delayed-Action Preparations Prodrugs.
Pharma Action Antipsychotic Agents 		Ann Med Psychol (Paris) 2(4):642;1976; C R Soc Biol (Paris) 1979;173(4):979; Cur Ther Res 20(2):177;1976; Farmakol Toksikol 38(4):393;1975; Pol Tyg Lek 32(44):1725;1977; Psychiatr Pol 10(5):479;1976; Vrach Delo 1980;(1):93FLUPHENAZINE; PROLIXIN DECANOATE; FLUPHENAZINE DECANOATE
brondiletten retard  77124-30-2 Benzeneacetic acid, alpha-hydroxy-alpha-phenyl-, 2-(diethylamino)ethyl ester, hydrochloride, mixt. with 5-ethyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione, 1-hexyl-3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione and N,N,4-trimethyl-gamma-phenylbenzenepropana  *Benactyzine *Phenobarbital *Propylamines Drug Combinations Theobromine/*analogs & derivatives Delayed-Action Preparations. Med Monatsschr 29(11):513;1975; Med Welt 26(38):1733;1975; Ther Ggw 115(12):2104;1976
poly(lactic acid)  26100-51-6   *Polymers *Lactic Acid Delayed-Action Preparations Membranes, Artificial Dental Implants Drug Delivery Systems. Am J Obstet Gynecol 122(1):90;1975; Am J Obstet Gynecol 135(3):419;1979; Invest Urol 16(1):48;1978; J Pharm Sci 64(1):115;1975
tardyferon  75285-30-2 Tardyferon  *Mucins *Ferrous Compounds Drug Combinations Delayed-Action Preparations. Acta Haematol Pol 7(4):321;1976; Pol Tyg Lek 29(38):1637;1974; Pol Tyg Lek 32(1):21;1977; Pol Tyg Lek 32(26):1017;1977
adrenocorticotropin zinc  53468-06-7   *Cosyntropin Delayed-Action Preparations.
Pharma Action Hormones 		Clin Exp Immunol 20(1):55;1975; J Endocrinol 59(2):xxix;1973; Lancet 1(7904):456;1975; Ned Tijdschr Geneeskd 1981;125(8):321; Z Neuropathol Endokrynolog Pol 29:121;1978CORTROPHIN-ZINC
quinidine arabogalactane sulfate  54692-74-9   Quinidine/*analogs & derivatives Delayed-Action Preparations. Lille Med 16(Suppl 1):234;1971

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