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Vitamin A

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Definition: Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of CAROTENOIDS found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.  /ther use: coordinate disease with /drug ther, not /diet ther   
Pharmacological Action Vitamins
Examples Tretinoin 		Other names Retinol; All Trans Retinol; Vitamin A1; Aquasol A; All-Trans-Retinol; 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl); 11-cis-RetinolDrugs* : VITAMIN A; AQUASOL A
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
APDDR-0901  0   *Benzamidines *Plant Extracts *Vitamin A Acne Vulgaris/drug therapy. Eur J Dermatol. 2011 Nov-Dec;21(6):959-65
vitamin A-aldehyde-dihydropyridine-ethanolamine  0   Lipofuscin/*analogs & derivatives Vitamin A/*analogs & derivatives. J Biol Chem. 2009 Jul 24;284(30):20155-66
vitamin A-aldehyde-dihydropyridine-phosphatidylethanolamine  0   Lipofuscin/*analogs & derivatives Vitamin A/*analogs & derivatives. J Biol Chem. 2009 Jul 24;284(30):20155-66
7,8-dihydroretinol  0   Vitamin A/*analogs & derivatives. Biochemistry 2007 Feb 20;46(7):1811-20
13,14-dihydroretinol  0   Vitamin A/*analogs & derivatives. J Biol Chem 2004 Nov 26;279(48):50230-42
retinyl N-formyl aspartamate  0   Vitamin A/*analogs & derivatives. J Am Acad Dermatol 2006 Aug;55(2):220-4
9-retinyl succinate  0   Vitamin A/*analogs & derivatives. PLoS Med 2005 Nov;2(11):e333
4-hydroxy-retinol  0   Vitamin A/*analogs & derivatives Retinoids. Life Sci. 2005 Feb 18;76(14):1613-22
trans-sodium crocetinate  0   Vitamin A/*analogs & derivatives. Neurosci Lett 2003 Dec 4;352(2):97-100
4-hydroxybenzylretinone  0   Vitamin A/*analogs & derivatives. Anticancer Res 2001 Nov-Dec;21(6A):3839-44
(9R,10S)-13-cis-11,12-didehydro-9,10-dihydro-10-hydroxyretinol  0   Vitamin A/*analogs & derivatives. J Org Chem 2002 Jan 25;67(2):420-5
retinyl 3,4,5-trimethoxybenzyl ether  0   Vitamin A/*analogs & derivatives. Anticancer Drug Des 1998 Apr;13(3):159-82
O-tocopherylsuccinyl O-ethyl ferulate conjugate  0   *Coumaric Acids Vitamin A/*analogs & derivatives. FEBS Lett 1997 Nov 24;418(1-2):15-8
3,4-didehydroretinyl acetate  0   Vitamin A/*analogs & derivatives. Teratology 1996 Apr;53(4):237-44
13,14-dihydroxyretinol  157153-38-3   Vitamin A/*analogs & derivatives. J Biol Chem 1995 Aug 11;270(32):18871-4
retinylglucose  29880-05-5   *Glucosides Vitamin A/*analogs & derivatives Growth Substances. Int J Vitam Nutr Res 1992;62(4):298-302
14-hydroxy-4,14-retro-retinol  139257-77-5   Vitamin A/*analogs & derivatives Retinoids. Science 1991;254(5038):1654
retinylglucuronide  16639-19-3   *Glucuronates Vitamin A/*analogs & derivatives. Methods Enzymol 1990;189:136
3-dehydroretinol palmitate  95632-86-3 Retinol, 3,4-didehydro-, hexadecanoate  Vitamin A/*analogs & derivatives. Vision Res 1988;28(9):959
vitamin A, vitamin E, vitamin K3 drug combination  135669-41-9   *Vitamin A *Vitamin E *Vitamin K Drug Combinations. Ortop Travmatol Protez 1989;(1):32
retinyl propionate  7069-42-3   Vitamin A/*analogs & derivatives. Br J Dermatol 1988;118(2):167
allantoin, hyaluronic acid, vitamin A, vitamin E drug combinatinon  0   *Allantoin *Hyaluronic Acid *Vitamin A *Vitamin E Drug Combinations. Gynakol Rundsch 1987;27(2):79
vitamin A, vitamin E drug combination  70713-06-3   *Vitamin A *Vitamin E Drug Combinations. Farmakol Toksikol 1986;49(2):71
fatty acid, fat-soluble vitamin and phospholipid emulsion  0   *Emulsions *Fatty Acids *Phospholipids *Vitamin A *Vitamin D.
Pharma Action Fat Emulsions, Intravenous 		Gematol Transfuziol 1985;30(12):44
retinyl linoleate  631-89-0   Vitamin A/*analogs & derivatives. Clin Chem 1986;32(1 Pt 1):35
perhydroretinol  96304-50-6   Vitamin A/*analogs & derivatives. J Cell Physiol 1985;124(1):120
Plethoryl  100216-56-6 Retinol, 2-amino-1,6,6a,7,8,9a-hexahydro-7-hydroxy-8-(hydroxymethyl)-, (6aS-(6aalpha,7alpha,8beta,9aalpha))  *Cyclohexanones Drug Combinations Triiodothyronine/*analogs & derivatives Vitamin A/*analogs & derivatives. Gastroenterol Clin Biol 1984;8(10):770
retinyl stearate  631-87-8   Vitamin A/*analogs & derivatives. Cancer Treat Rep 1984;68(9):1125
4-azidoretinol  92484-22-5 Retinol, 4-azido-, (SP-4-2)  *Azides Vitamin A/*analogs & derivatives. Biochem Biophs Res Commun 1984;122(2):577
retinol oleate  631-88-9   Vitamin A/*analogs & derivatives. J Lipid Res 1984;25(6):638
4,4-difluororetinyl palmitate  91484-94-5 Retinol, 4,4-difluoro-, hexadecanoate  Vitamin A/*analogs & derivatives. Biochim Biophys Acta 1984;799(2):128
4,4-difluororetinol  90660-21-2   Vitamin A/*analogs & derivatives. Biochim Biophys Acta 1984;799(2):128
4-oxoretinol  62702-55-0   Vitamin A/*analogs & derivatives. Biochim Biophys Acta 1984;799(2):128
4,4-difluororetinyl acetate  90660-22-3 Retinol, 4,4-difluoro-, (5'alpha,10alpha)  Vitamin A/*analogs & derivatives. Biochim Biophys Acta 1984;799(2):128
perhydromonoeneretinyl phosphate  85733-82-0 1-Cyclohexene-1-nonanol, 6,6-dimethyl-, dihydrogen phosphate  Vitamin A/*analogs & derivatives. Biochem J 1982;208(3):865
retinyl hexadecyl ether  85563-59-3 Cyclohexene, 2-(9-(hexadecyloxy)-3,7-dimethyl-1,3,5,7-nonatetraenyl)-1,3,3-trimethyl-, (all-E)  Vitamin A/*analogs & derivatives. Biochim Biophys Acta 1983;750(2):223
streptobicillin depot  85160-58-3 D-Streptamine, O-2-deoxy-2- (methylamino)-alpha-L-glucopyranosyl-(1-2)-O-5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl-(1-4)-N,N'-bis(aminoiminomethyl)-, sulfate (2:3) (salt), mixt. with N,N'-bis(phenylmethyl)-1,2-ethanediamine bis((2S-(2alpha,5alpha,6beta))  *Penicillin G Benzathine *Streptomycin *Vitamin A Drug Combinations Delayed-Action Preparations. Vet Med Nauki 1982;19(5):85
regepithel  62213-87-0   *Pantothenic Acid *Thiamine *Vitamin A Drug Combinations. Klin Oczna 1982;83(10-12):505
5,6-epoxyretinylphosphate  80134-56-1 Retinol, 5,6-epoxy-5,6-dihydro-, dihydrogen phosphate  Vitamin A/*analogs & derivatives. J Lipid Res 1981;22(7):1069
anhydrovitamin A  1224-78-8   Vitamin A/*analogs & derivatives. Biophys J 1979;25(3):443
vitamin A, pentifyllin, nicotinic acid, and vitamin E combination  76584-56-0 Vitamin A, mixt. with 1-hexyl-3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione, 3-pyridinecarboxylic acid and vitamin E  *Nicotinic Acids *Vitamin A *Vitamin E Drug Combinations Theobromine/*analogs & derivatives.
Pharma Action Vitamins 		Med Welt 1980;31(35):1255
vitamin A2  79-80-1   Vitamin A/*analogs & derivatives. Experientia 1980;36(3):317
retinyl methyl ether  32450-56-9 2-(9-methoxy-3,7-dimethyl-1,3,5,7-nonatetraenyl)-1,3,3-trimethylcyclohexene  Vitamin A/*analogs & derivatives. Science 207(4428):311;1980
anhydrovitamin A(2)  6890-94-4 2-Cyclohexen-1-ol, 4-(3,7-dimethyl-2,4,6,8-nonatetraenylidene)-3,5,5-trimethyl  Vitamin A/*analogs & derivatives. Biochem J 177(3):791;1979
15-methyl retinone  67517-37-7 3,5,7,9-Decatetraen-2-one, 4,8-dimethyl-10-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all-E)  Vitamin A/*analogs & derivatives. Biochim Biophys Acta 529(3):438;1978
15-methyl retinol  67517-42-4 Retinol-6,7-14C2, 15-methyl  Vitamin A/*analogs & derivatives. Biochim Biophys Acta 529(3):438;1978
15-dimethylretinol  67517-39-9 Retinol, 15,15-dimethyl  Vitamin A/*analogs & derivatives. BBA 529(3):438;1978
axerophthene  6895-29-0   Vitamin A/*analogs & derivatives. Cancer Res 38:1734;1978
3-hydroxyretinol  6890-93-3   Vitamin A/*analogs & derivatives. Biochem J 168(3):557;1977
boric acid, vitamin A, zinc sulfate drug combination  0   *Boric Acids *Vitamin A *Zinc Compounds Drug Combinations. Vutr Bol 16(4):89;1977
retinol palmitate  79-81-2 retinol, hexadecanoate  Vitamin A/*analogs & derivatives.
Pharma Action Antioxidants ; Anticarcinogenic Agents 		Biochem Soc Trans 1979;7(5):937; Chem Biol Interact 1980;29(2):209; J Assoc Off Anal Chem 62(2):283;1979; J Biol Chem 253(5):1627;1978; J Cancer Res Clin Oncol 93(2):149;1979; JNCI 58(5):1347;1977; Vopr Med Khim 22(3):388;1976; Vopr Pitan 5:46;1978VITAMIN A SOLUBILIZED; VITAMIN A PALMITATE; DEL-VI-A; VI-DOM-A; ALPHALIN; AQUASOL A; VITAMIN A; AFAXIN
Tylavit-sulfa  65702-93-4 tylosin, mixt. with 4-amino-N-(4,6-dimethyl-2- pyrimidinyl)benzenesulfonamide & retinol  *Sulfamethazine *Vitamin A *Tylosin Drug Combinations. Med Weteryn 32(11):684;1976
retinylphosphate galactose  35795-65-4 Retinol, galactosyl hydrogen phosphate  *Galactolipids Vitamin A/*analogs & derivatives. J Biol Chem 251(16):4986;1976
retinol phosphate  53859-19-1 Retinol, dihydrogen phosphate  Vitamin A/*analogs & derivatives. Anal Biochem 1980;102(1):243; Biochem J 172:123;1978; FEBS Lett 1979;107(2):375; J Biol Chem 252(8):2575;1977; J Lipid Res 17(3):220;1976; Prikl Biokhim Mikrobiol 14(4):558;1978
retinol acetate  127-47-9   Vitamin A/*analogs & derivatives.
Pharma Action Adjuvants, Immunologic ; Anticarcinogenic Agents 		Biochem J 146(2):501;1975; Cancer Res 1979;39(10):3977; Cancer Res 1980;40(4):1109; Cancer Res 1980;40(4):1140; Cancer Res 36(3):996;1976; Cancer Res 38:1497-501;1978; Cancer Res 38:1734;1978; Chem Biol Interact 16:251;1977; Cleft Palate J 15(4):378;1978; Clin Exp Dermatol 3(2):173;1978; Connect Tissue Res 6(2):101;1978; Exp Mol Pathol 24(3):405;1976; Invest Urol 16(5):376;1979; JNCI 1979;63(6):1359; JNCI 1980;64(3):655; JNCI 59(6):1717;1977; JNCI 60(5):1035;1978; Nature 267(5612):620;1977; Oncology 1980;37(2):65; Vopr Med Khim 22(3):388;1976
Repredsol  79234-30-3 Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-, mixt. with boric acid (H3BO3), disodium hydrogen phosphate & vitamin A  *Boric Acids *Prednisolone *Vitamin A Drug Combinations Administration, Topical Colitis, Ulcerative. Vutr Boles 12(4):92;1973
5,6-monoepoxy vitamin A  512-39-0 5,6-epoxy-5,6-dihydroretinol  Vitamin A/*analogs & derivatives. Arch Biochem Biophys 1997 Jul 1;343(1):13-8

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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