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Nucleic Acid Synthesis Inhibitors

More information in Books or onNLM PubMed
Definition: Compounds that inhibit cell production of DNA or RNA.  despite X refs, coord IM with DNA /biosyn (IM) or RNA /biosyn (IM) or specific nucleic acid /biosyn (IM); DF: NUCLEIC ACID SYN INHIB   
Examples Reverse Transcriptase Inhibitors
Other names Synthesis Inhibitors, RNA; Synthesis Inhibitors, DNA; Inhibitors, RNA Synthesis; Inhibitors, Nucleic Acid Synthesis; Inhibitors, DNA Synthesis; RNA Synthesis Inhibitors; DNA Synthesis Inhibitors
Substances having this pharmacologic action: 2,6-diaminopurine; Fluoroquinolones; Alpha-Amanitin; Fleroxacin; Phleomycins; Dichlororibofuranosylbenzimidazole; Anisomycin; Arabinofuranosylcytosine Triphosphate; Amanitins; Chromomycins; Ciprofloxacin; Zinostatin; Nalidixic Acid; Rifampin; Rimantadine; Teniposide; Mitomycin; Nitracrine; 6-Mercaptopurine; Ofloxacin; Enoxacin; Pefloxacin; Cytochalasin D; Chromomycin A3; Nogalamycin; Norfloxacin; Novobiocin; Oxolinic Acid; Methotrexate; Methylazoxymethanol Acetate; Fusaric Acid; Distamycins; Echinomycin; Edeine; Hydroxyphenylazouracil; Hydroxyurea; Idoxuridine; Plicamycin; Dactinomycin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
artepillin C  72944-19-5   *Phenylpropionates Nucleic Acid Synthesis Inhibitors. Gan To Kagaku Ryoho 1996 Nov;23(13):1855-9
picornain 2A, Picornavirus  EC 3.4.22.29   *Cysteine Endopeptidases *Viral Proteins Protein Synthesis Inhibitors Nucleic Acid Synthesis Inhibitors. J Virol 1988;62(11):4216

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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