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Oxolinic Acid

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Definition: Synthetic antimicrobial related to NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.     
Pharmacological Action Anti-Infective Agents; Anti-Infective Agents, Urinary; Nucleic Acid Synthesis Inhibitors
Other names Acid, Oxolinic; Gramurin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1-ethyl-1,4-dihydro-6,7-methylenedioxy-4-oxo-quinoline-3-carboxilic acid  0   Oxolinic Acid/*analogs & derivatives. J Pharm Biomed Anal 1998 Oct;18(1-2):267-70
5,8-dihydro-8-oxo-2H-1,3-dioxolo(4,5-g)quinoline-7-carboxylic acid  19746-58-8   Oxolinic Acid/*analogs & derivatives. Antimicrob Agents Chemother 1980;18(1):45
miloxacin  37065-29-5 5,8-dihydro-5-methoxy-8-oxo-1,3-dioxolo(4,5- g)quinoline-7-carboxylic acid  Oxolinic Acid/*analogs & derivatives. Radioisotopes 28(11):687;1979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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