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Alpha-Amanitin
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Definition
: A cyclic octapeptide with a thioether bridge between the cystine and tryptophan. It inhibits RNA POLYMERASE II. Poisoning may require LIVER TRANSPLANTATION.
Pharmacological Action
Poisons
;
Nucleic Acid Synthesis Inhibitors
See Also
Mushroom Poisoning
Other names
Alpha Amanitine; Alpha Amanitin; Alpha-
Amanitine