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Idoxuridine
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Definition
: An analog of DEOXYURIDINE that inhibits viral DNA synthesis. The drug is used as an antiviral agent.
Pharmacological Action
Antiviral Agents
;
Nucleic Acid Synthesis Inhibitors
Other names
Iododeoxyuridine; 5-
Iodo-
2'-
deoxyuridine; IUdR; OftanIDU; Oftan IDU; NSC39661; NSC 39661; Liquifilm, Herplex; Idoxuridine, 3H Labeled; Idoxuridine, 131I Labeled; Idoxuridine, 125I Labeled; Idoxuridine, 123I Labeled; 5 Iododeoxyuridine; 5 Iodo 2' deoxyuridine; 3H-
Labeled Idoxuridine; 131I-
Labeled Idoxuridine; 125I-
Labeled Idoxuridine; 123I-
Labeled Idoxuridine; Stoxil; SK&F-
14287
Drugs
*
:
DENDRID
;
HERPLEX
;
STOXIL
Substance
CAS Registry & name
Categories
Source
Drugs
*
3'-
O-
(3-
benzenesulfonylfuroxan-
4-
yl)-
5-
iodo-
2'-
deoxyuridine
0
*Oxadiazoles
Idoxuridine/*analogs & derivatives
Iodine Radioisotopes.
Nucl Med Biol 2005 Aug;32(6):641-5
5-
iodo-
3'-
O-
nitro-
2'-
deoxyuridine
0
Idoxuridine/*analogs & derivatives.
Eur J Pharm Sci 2003 Jul;19(4):305-13
5-
astato-
2'-
deoxyuridine
63473-09-6
Idoxuridine/*analogs & derivatives
Astatine.
Cancer Res 1996 Mar 15;56(6):1204-9
dioleoyl iododeoxyuridine
0
Idoxuridine/*analogs & derivatives.
Biochemistry 1994 Nov 29;33(47):14073-80
idoxuridine-
bleomycin protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Bleomycin
Idoxuridine.
Cancer Res 1993 Mar 15;53(6):1293-6
3'-
azido-
2',3'-
dideoxy-
5-
iodouridine
85236-92-6
Idoxuridine/*analogs & derivatives
Thymidine Kinase/antagonists & inhibitors.
Biochem Pharmacol 1993 Jan 7;45(1):223-30
poly(dA-
IdU)
59164-41-9
*Idoxuridine
*Poly A-U.
Nucleic Acids Res 1992 Mar 11;20(5):1109-12
3-
methyl-
5-
(2-
iodovinyl)-
2'-
deoxyuridine
118068-34-1
Idoxuridine/*analogs & derivatives.
Drug Des Deliv 1988;3(3):223
2'-
iodo-
2'-
deoxyuridine
4753-03-1 Uridine, 2'-
deoxy-
2'-
iodo
*Idoxuridine
Isomerism.
Mol Pharmacol 1983;23(1):146
5-
iodouridine
1024-99-3
Idoxuridine/*analogs & derivatives.
J Virol Methods 1982;5(3-4):209
diacetylidoxuridine
0
Idoxuridine/*analogs & derivatives.
Arch Ophthalmol 1981;99(9):1618
5-
(2-
iodovinyl)-
2'-
deoxyuridine
87727-68-2
Idoxuridine/*analogs & derivatives.
Pharma Action
Antiviral Agents
J Biol Chem 1981;256(12):5973
5'-
deoxy-
5'-
iodouridine
14259-58-6 uridine, 5'-
deoxy-
5'-
iodo
Idoxuridine/*analogs & derivatives.
Int J Radiat Biol 1981;39(2):185
AIdUrd
56045-73-9 5'-
amino-
2',5'-
dideoxy-
5-
iodouridine
Idoxuridine/*analogs & derivatives.
Adv Ophthalmol 1979;38:90; Ann NY Acad Sci 255:332;1975; Antimicrob Agents Chemother 15(1):101;1979; Antimicrob Agents Chemother 16(1):92;1979; Biochim Biophys Acta 1980;606(2):236; J Biol Chem 251(16):4833;1976; J Biol Chem 254(20):10449;1979; J Virol 15(5):1284;1975; Proc Soc Exp Biol Med 156:92;1977