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Zinostatin

More information in Books or onNLM PubMed
Definition: An enediyne that alkylates DNA and RNA like MITOMYCIN does, so it is cytotoxic.     
Pharmacological Action Antibiotics, Antineoplastic; Cytotoxins; Nucleic Acid Synthesis Inhibitors 		Other names Neocarzinostatin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
transferrin-neocarzinostatin conjugate  0   *Zinostatin *Transferrin. Jpn J Cancer Res 1990;81(1):91
neocarzinostatin chromophore hydrogen bromide adduct  0   Zinostatin/*analogs & derivatives. J Antibiot (Tokyo) 1988;41(9):1272
aponeocarzinostatin  101359-79-9   *Apoproteins *Zinostatin. Chem Pharm Bull (Tokyo) 1986;34(12):5180
NF protocol  0   *Antineoplastic Combined Chemotherapy Protocols Fluorouracil Zinostatin. Gan To Kagaku Ryoho 1984;11(1):68
NFO protocol  0   *Antineoplastic Combined Chemotherapy Protocols Fluorouracil Zinostatin Picibanil. Gan To Kagaku Ryoho 1984;11(1):68
NHO protocol  0   *Antineoplastic Combined Chemotherapy Protocols Fluorouracil/analogs & derivatives Zinostatin Picibanil. Gan To Kagaku Ryoho 1984;11(1):68
poly(maleic acid-styrene)neocarzinostatin  0   *Maleic Anhydrides *Polystyrenes Zinostatin/*analogs & derivatives.
Pharma Action Antineoplastic Agents 		Gan 1982;73(2):278
neocarzinostatin chromophore  81604-85-5   Zinostatin/analogs & derivatives.
Pharma Action Antibiotics, Antineoplastic ; Enzyme Inhibitors 		Biochemistry 1981;20(19):5602

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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