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Thiazines

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Definition:      
Examples Cephalosporins; Chlormezanone; Nifurtimox; Piroxicam; Thiadiazines; Xylazine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Azarga  0   *Sulfonamides *Thiazines *Timolol Drug Combinations Antihypertensive Agents Glaucoma/drug therapy. Oftalmologia. 2011;55(3):38-46
4,5-dihydrothiazinogeldanamycin  0   *Thiazines *Lactams, Macrocyclic. Biosci Biotechnol Biochem. 2011;75(10):2042-5.
LY2811376  0   *Pyrimidines *Thiazines. J Neurosci. 2011 Nov 16;31(46):16507-16
BTZO-15 compound  0   *Pyridines *Thiazines. PLoS One. 2011;6(8):e23256.
MCF201-89  0   *Thiazines Radiation-Protective Agents. Int J Radiat Oncol Biol Phys. 2011 Jul 1;80(3):860-8
5-carboxymeloxicam  0   *Thiazines *Thiazoles. Bioanalysis. 2009 Apr;1(1):63-70
2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone  0   *Cyclic S-Oxides *Thiazines 11-beta-Hydroxysteroid Dehydrogenases/antagonists & inhibitors. Biochem Pharmacol 2011 Apr 15;81(8):1028-35
benzo(b)cyclohepta(e)(1,4)thiazine  0   *Thiazines. In Vivo 2011 Jan-Feb;25(1):41-8
2-(3-benzoyl-4-hydroxy-1,1-dioxido-2H-benzo(e)(1,2)thiazin-2-yl)-N- (3-(trifluoromethyl)phenyl)acetamide  0   *Acetamides *Thiazines. Chem Pharm Bull (Tokyo). 2011;59(1):46-52
2-pyridin-2-yl-4H-1,3-benzothiazin-4-one  0   *Pyridines *Thiazines. Chem Biol 2010 Dec 22;17(12):1282-94
2-(4-hydroxy-2,6-dimethylanilino)-5,6-dihydro-4H-1,3-thiazin-3-ium chloride  0   *Aniline Compounds *Thiazines. Acta Crystallogr C. 2010 Dec;66(Pt 12):o593-5
6-hydroxy-3-(2-oxoindolin-3-ylideneamino)-2-thioxo-2H-1,3-thiazin-4(3H)-one  0   *Indoles *Thiazines. J Hazard Mater 2010 Jun 15;178(1-3):287-92
4-hydroxy-2,6-dimethyl-5,6-dihydro-4H-1,3-thiazine  0   *Thiazines Monophenol Monooxygenase/antagonists & inhibitors. J Pharm Pharmacol 2009 Dec;61(12):1657-63
N-(3',4'-dichlorobiphenyl-4-yl)-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide  0   *Cyclic S-Oxides *Thiazines. Biochem Pharmacol 2010 May 15;79(10):1445-54
sodium phenothiazinate  0   *Thiazines. Chem Pharm Bull (Tokyo). 2009 Nov;57(11):1300-2
1,3-benzthiazinan-4-one  0   *Thiazines. Bioorg Med Chem. 2009 Aug 1;17(15):5369-73
3-(10'-Phenothiazinyl)propane-1-sulfonate  0   *Thiazines *Alkanesulfonic Acids. Anal Biochem. 2009 Sep 1;392(1):54-8
N-(5,6-dimethyl-3-oxo-8-((4,4,5,5,5-pentafluoropentyl)thio)-2,3-dihydro-1H-imidazo(5,1-c)(1,4)thiazin-1-ylidene)-4-methylbenzenesulfonamide  0   *Imidazoles *Thiazines. J Pharmacol Sci 2009 Jun;110(2):201-11
2-(2-methyl-1,4-dioxa-8-azaspiro(4.5)dec-8-yl)-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin-4-one  0   *Spiro Compounds *Thiazines. Science. 2009 May 8;324(5928):801-4
N-(1-(1-naphthyl)ethyl)-3,4-dihydro-2H-1,2-benzothiazin-4-amine 1,1-dioxide  0   *Cyclic S-Oxides *Thiazines. Acta Crystallogr C 2009 Feb;65(Pt 2):o46-50
3-(1-hydroxyethylidene)-2,5,7-trimethyl-2,3-dihydropyrido(3,2-e)(1,2)thiazin-4-one 1,1-dioxide  0   *Cyclic S-Oxides *Thiazines. Acta Crystallogr C 2008 Nov;64(Pt 11):o590-4
3-(hydroxy(phenyl)methyl)-2,5,7-trimethyl-2,3-dihydropyrido(3,2-e)(1,2)thiazin-4-one 1,1-dioxide  0   *Cyclic S-Oxides *Thiazines. Acta Crystallogr C 2008 Nov;64(Pt 11):o590-4
4-((5,6,7,8-tetrahydro-4-oxo-4H-(1)benzothieno(2,3-d)(1,3)thiazin-2-yl)amino)benzoic acid  0   *Thiazines 4-Aminobenzoic Acid/*analogs & derivatives P-Glycoproteins/antagonists & inhibitors. Bioorg Med Chem Lett 2008 Sep 1;18(17):4761-3
N-(4-chlorophenyl)-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxamide  0   *Thiazines. Acta Crystallogr C 2008 Jan;64(Pt 1):o4-6
N-(2-chlorophenyl)-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxamide  0   *Thiazines. Acta Crystallogr C 2008 Jan;64(Pt 1):o4-6
ascidiathiazone B  0   *Thiazines. J Nat Prod 2007 Jun;70(6):936-40
ascidiathiazone A  0   *Thiazines. J Nat Prod 2007 Jun;70(6):936-40
5-acetyl-2,3-dihydro-4H-thiazine  0   *Thiazines. Chem Rev 2006 Jun;106(6):2299-319
6-(4-fluorophenyl)-8-phenyl-2,3-dihydro-4H-imidazo(5,1-b)(1,3)thiazin-4-one  0   *Imidazoles *Thiazines. Acta Crystallogr C. 2007 Mar;63(Pt 3):o160-2
GSK188909  0   *Thiazines. Neurochem 2007 Feb;100(3):802-9
YM 58875  0   *Pyridines *Thiazines. Biomed Chromatogr 2006 Dec;20(12):1328-35
etopropazine  0   *Thiazines. Electrophoresis 2006 Sep;27(17):3410-9
7-hydroxymethyl-8,8-dimethyl-4,8-dihydrobenzol(1, 4)thiazine-3,5-dione-(2-O-caffeoyl)-beta-D-glucopyranoside  0   *Monosaccharides *Thiazines. Fitoterapia. 2006 Apr;77(3):236-9
7-(beta-D-glucopyranosyloxymethyl)-8,8-dimethyl-4,8-dihydrobenzo(1,4)thiazine-3,5-dione  0   *Glucosides *Thiazines. Nat Prod Res. 2005 Sep;19(6):585-9
5-(1,1-dioxido-1,2-thiazinan-2-yl)-N-(4-fluorobenzyl)-8-hydroxy-1,6-naphthyridine-7-carboxamide  0   *Naphthyridines *Thiazines. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Jun 5;820(1):69-76
SSR125543  0   *Thiazines *Hydrocarbons, Halogenated. Eur J Pharmacol. 2004 Aug 16;497(1):49-53
thiaplidiaquinone B  0   *Thiazines *Benzoquinones. J Med Chem 2005 May 5;48(9):3410-6
thiaplidiaquinone A  0   *Thiazines *Benzoquinones. J Med Chem 2005 May 5;48(9):3410-6
4H-1,4-benzothiazine-2-carbonitrile 1,1-dioxide  0   *Nitriles *Thiazines. Bioorg Med Chem. 2005 Jan 3;13(1):141-55
2,3-dihydro-1-(N-(2-(3,4-dimethoxyphenyl)ethyl)-N-methylaminopropionyl)-1H-pyrido(2,3-b)(1,4)thiazine  0   *Anisoles *Thiazines. Biol Pharm Bull 2004 Sep;27(9):1364-70
2,3-dihydro-1-(N-(2-(3,4-dimethoxyphenyl)ethyl)-N-methylaminoacetyl)-1H-pyrido(2,3-b)(1,4)thiazine  0   *Anisoles *Thiazines. Biol Pharm Bull 2004 Sep;27(9):1364-70
10H-phenothiazine-1-acylhydrazone  0   *Hydrazones *Thiazines. Bioorg Med Chem. 2004 Jun 15;12(12):3149-58
2,6-bis-methylsulfanyl-(1,3,5)thiadiazine-4-thione  0   *Thiazines *Thiones. Anal Sci. 2004 Oct;20(10):1423-6
3-amino-2-imino-3,4-dihydro-2H-1,3-benzothiazin-4-one  0   *Thiazines. Biochem Pharmacol 2004 May 15;67(10):1907-16
2-amino-8-chloro-5,5-dioxo(1,2,4)triazolo(2,3-b)(1,4,2)benzodithiazine  0   *Thiazines *Triazoles. Bioorg Med Chem. 2003 Apr 3;11(7):1259-67
tetrahydro-2H-1,3,5-thiadiazine-2-thione  0   *Thiazines *Thiones. Arzneimittelforschung. 2003;53(7):526-31
6-cyano-2,2-dimethyl-4-(1-oxo-2-cyclopenten-2-yl)-3,4-dihydro-2H-1,4-benzothiazine  0   *Thiazines. J Med Chem 2003 Aug 14;46(17):3670-9
2,2-dimethyl-4-(1-oxo-2-cyclopenten-2-yl)-6-trifluoromethyl-3,4-dihydro-2H-1,4-benzothiazine  0   *Thiazines. J Med Chem 2003 Aug 14;46(17):3670-9
2,2-dimethyl-6-nitro-4-(1-oxo-2-cyclopenten-2-yl)-3,4-dihydro-2H-1,4-benzothiazine  0   *Thiazines. J Med Chem 2003 Aug 14;46(17):3670-9
1H-pyrrolo(1,2-c)(1,3)thiazine  0   *Pyrroles *Thiazines. Acta Pol Pharm. 2003 Jan-Feb;60(1):67-74
2-(N-(4-chlorophenyl)-N-methylamino)-4H-pyrido(3,2-e)-1,3-thiazin-4-one  0   *Pyridines *Thiazines Receptors, AMPA/antagonists & inhibitors. J Pharmacol Exp Ther 2003 Jul;306(1):66-72
pyrido-1,2-thiazine  0   *Pyridines *Thiazines. Acta Pol Pharm 2002 Nov-Dec;59(6):439-42
2,6-dimethyl-3-isopropyl-1,2-benzothiazin-3,4-diol 1,1-dioxide  0   *Cyclic S-Oxides *Thiazines. Eur J Pharm Sci 2002 Sep;16(4-5):221-8
6-methyl-3-isopropyl-2H-1,2-benzothiazin-4(3H)-one 1,1-dioxide  0   *Cyclic S-Oxides *Thiazines. Eur J Pharm Sci 2002 Sep;16(4-5):221-8
basic blue 9  0   *Thiazines. Bioresour Technol 2002 Apr;82(2):139-45
6,12-dihydro-3-methoxy-1-benzopyrano(3,4-b)-(1,4)benzothiazin-6-one  0   *Thiazines. Biol Pharm Bull 2002 Mar;25(3):335-41
triazolylphenothiazine  0   *Thiazines. Boll Chim Farm 2002 May-Jun;141(3):192-6
8-(4-bromophenyl)-5-methyl-8H-(1,4)thiazino(3,4-c)oxadiazol-3-one  0   *Oxadiazoles *Thiazines. J Med Chem 2002 Aug 1;45(16):3475-81
5-methyl-8-phenyl-8H-(1,4)thiazino(3,4-c)(1,2,4)oxadiazol-3-one  0   *Oxadiazoles *Thiazines. J Med Chem 2002 Aug 1;45(16):3475-81
1,4-benzothiazine  0   *Thiazines. Chem Pharm Bull (Tokyo) 2001 Sep;49(9):1132-7
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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