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Tetrahydronaphthalenes
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Definition
: Partially saturated 1,2,3,4-tetrahydronaphthalene compounds.
Examples
8-Hydroxy-2-(di-n-propylamino)tetralin
;
Levobunolol
;
Mibefradil
;
Podophyllotoxin
;
Tetralones
Other names
Tetralins
Substance
CAS Registry & name
Categories
Source
Drugs
*
4-
((1,3-
dioxooctahydro-
2H-
4,7-
methanoisoindol-
2-
yl))-
N-
(8-
oxo-
5,6,7,8-
tetrahydronaphthalen-
1-
yl)cyclohexylcarboxamide
0
*Heterocyclic Compounds, 3-Ring
*Tetrahydronaphthalenes.
J Med Chem. 2012 Jan 26;55(2):697-708.
(S)-
7-
methoxy-
2-
aminotetraline
0
*Tetrahydronaphthalenes.
Biosci Biotechnol Biochem. 2011;75(11):2093-8
(4-
(3,4-
dichlorophenyl)-
1,2,3,4-
tetrahydronaphthalen-
1-
yl)dimethylammonium
0
*Tetrahydronaphthalenes.
Neuropsychopharmacology 2010 Dec;35(13):2564-78
confertifolin
0
*Furans
*Tetrahydronaphthalenes
Oils, Volatile.
Pharm Biol. 2010 Feb;48(2):187-90
A-
995662
0
*Tetrahydronaphthalenes.
Pain. 2010 Aug;150(2):319-26
6-
((2-
(4-
(biphenyl-
4-
yl)piperazin-
1-
yl)ethyl)(propyl)amino)-
5,6,7,8-
tetrahydronaphthalen-
1-
ol
0
*Biphenyl Compounds
*Piperazines
*Tetrahydronaphthalenes.
Bioorg Med Chem. 2010 Aug 1;18(15):5661-74
6-
hydroxy-
1,2,3,4-
tetrahydronaphthalene-
2-
carboxylic acid-
(1-
(4-
(3-
hydroxyphenyl)dimethylpiperidinylmethyl)methylpropyl)amide
0
*Piperidines
*Tetrahydronaphthalenes
Receptors, Opioid, kappa/antagonists & inhibitors.
J Med Chem 2010 Jul 22;53(14):5290-301
2-
(5,7-
difluoro-
1,2,3,4-
tetrahydronaphthalen-
3-
ylamino)-
N-
(1-
(2-
methyl-
1-
(neopentylamino)propan-
2-
yl)-
1H-
imidazol-
4-
yl)pentanamide
0
*Tetrahydronaphthalenes
Valine/*analogs & derivatives
Amyloid Precursor Protein Secretases/antagonists & inhibitors.
J Pharmacol Exp Ther 2010 Jul;334(1):269-77
2-
hydroxy-
3-
(4-
(4-
fluorobenzoyl)piperidino)tetralin
0
*Piperidines
*Tetrahydronaphthalenes
Fluorine Radioisotopes.
J Med Chem 2009 Mar 12;52(5):1358-69
2-
amino-
nonyl-
6-
methoxyl-
tetralin muriate
0
*Tetrahydronaphthalenes.
Acta Pharmacol Sin. 2010 May;31(5):616-28
NBRI17671
0
*Tetrahydronaphthalenes.
J Antibiot (Tokyo). 2010 May;63(5):237-43
2-
(4-
((benzylmethylamino)methyl)benzylidene)-
6-
(5-
piperidin-
1-
yl-
pentyloxy)-
3,4-
dihydro-
2H-
naphthalen-
1-
one
0
*Benzylamines
*Tetrahydronaphthalenes.
Bioorg Med Chem 2010 Mar 1;18(5):1749-60
2-
(4-
((benzylmethylamino)methyl)benzylidene)-
6-
(5-
diethylaminopentyloxy)-
3,4-
dihydro-
2H-
naphthalen-
1-
one
0
*Benzylamines
*Tetrahydronaphthalenes.
Bioorg Med Chem 2010 Mar 1;18(5):1749-60
JBIR-
22
0
*Pyrrolidinones
*Tetrahydronaphthalenes.
J Nat Prod. 2010 Apr 23;73(4):628-31
IT-
M-
07000
0
*Phenylpropionates
*Tetrahydronaphthalenes.
Biol Pharm Bull 2009 Dec;32(12):1997-2001
EC23 compound
0
*Tetrahydronaphthalenes
*Benzoic Acids.
Mol Biosyst 2009 May;5(5):458-71
EC19 compound
0
*Tetrahydronaphthalenes
*Benzoic Acids.
Mol Biosyst 2009 May;5(5):458-71
N-
(3-
cyano-
5-
fluoro-
4-
(methylsulfonamido)benzyl)-
3-
(5,5,8,8-
tetramethyl-
5,6,7,8-
tetrahydro-
naphthalen-
2-
yl)propanamide
0
*Sulfonamides
*Tetrahydronaphthalenes.
Bioorg Med Chem 2009 May 15;17(10):3557-67
1,3-
diphenyl-
1,2,3,4-
tetrahydro-
1-
naphthol
0
*Naphthols
*Tetrahydronaphthalenes.
Acta Crystallogr C 2009 Feb;65(Pt 2):o35-8
8-
methoxy-
2-
propionamidotetralin
0
*Tetrahydronaphthalenes.
Reproduction. 2008 Nov;136(5):533-41
1-
keto-
2-
(p-
dimethylaminobenzal)-
tetrahydronaphthalene
0
*Tetrahydronaphthalenes.
Spectrochim Acta A Mol Biomol Spectrosc. 2008 Sep;70(4):888-91
N-
(5,6,7,8-
tetrahydronaphthalen-
2-
yl)guanidine
0
*Guanidines
*Tetrahydronaphthalenes.
J Med Chem 2008 Jun 12;51(11):3304-12
2-
hydroxy-
5-
(3-
iodoprop-
2-
en-
1-
oxy)-
3-
(4-
phenylpiperidino)tetralin
0
*Piperidines
*Tetrahydronaphthalenes
Iodine Radioisotopes
Ligands.
Nucl Med Biol 2007 Nov;34(8):967-71
UVI 3003
0
*Coumaric Acids
*Tetrahydronaphthalenes
Retinoid X Receptors/agonists.
Proc Natl Acad Sci U S A 2007 Oct 30;104(44):17323-8
CD 3254
0
*Coumaric Acids
*Tetrahydronaphthalenes
Retinoid X Receptors/agonists.
Proc Natl Acad Sci U S A 2007 Oct 30;104(44):17323-8
1-
acetyl-
5-
bromo-
2,3-
dihydro-
N-
(1,2,3,4-
tetrahydro-
1-
naphthalenyl)-
1H-
Indole-
7-
sulfonamide
0
*Sulfonamides
*Tetrahydronaphthalenes.
Biol Pharm Bull 2007 Mar;30(3):502-7
bupleurumin
0
*Lactones
*Tetrahydronaphthalenes.
Arch Pharm Res 2007 May;30(5):561-4
ST-
1942
0
*Tetrahydronaphthalenes.
Neuropsychopharmacology. 2007 Jun;32(6):1302-11
N-
methyl-
N-
(6-
methoxy-
1-
phenyl-
1,2,3,4-
tetrahydronaphthalen-
2-
ylmethyl)aminomethylcarboxylic acid
0
*Tetrahydronaphthalenes.
Alcohol Alcohol 2007 Jan-Feb;42(1):11-8
7,8-
dihydroxycalamenene
0
*Tetrahydronaphthalenes.
Org Lett 2006 Nov 9;8(23):5315-6
carneic acid B
0
*Tetrahydronaphthalenes.
J Nat Prod 2006 Aug;69(8):1198-202
carneic acid A
0
*Tetrahydronaphthalenes.
J Nat Prod 2006 Aug;69(8):1198-202
AS 19 compound
0
*Pyrazoles
*Tetrahydronaphthalenes.
Behav Brain Res 2005 Aug 30;163(1):136-40
isocatalpanol
0
*Tetrahydronaphthalenes.
Magn Reson Chem 2005 Jul;43(7):582-4
burseranin
0
*Tetrahydronaphthalenes.
Chem Pharm Bull (Tokyo). 2005 Feb;53(2):229-31
(5,6,7,8-
tetrahydronaphthalen-
1-
yl)-
(2-
(1H-
tetrazol-
5-
yl)phenyl)amine
0
*Tetrahydronaphthalenes
*Tetrazoles.
J Pharmacol Exp Ther 2005 Apr;313(1):250-9
4-
(2-
methylthiophenyl)-
N-
(1,2,3,4-
tetrahydronaphthalen-
1-
yl)-
1-
piperazinehexanamide
0
*Piperazines
*Tetrahydronaphthalenes
Receptors, Serotonin/agonists.
J Med Chem 2004 Dec 16;47(26):6616-24
5-
hydroxy-
2-
(N-
propyl-
N-
(5'-
fluoropentyl))aminotetralin
0
*Tetrahydronaphthalenes
Fluorine Radioisotopes
Receptors, Dopamine D2
Receptors, Dopamine D2/agonists.
Nucl Med Biol 2004 Apr;31(3):303-11
ST1214
0