ψ 
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Guaiacol 
An agent thought to have disinfectant properties and used as an expectorant. (From Martindale, The Extra Pharmacopoeia, 30th ed, p747)     
Pharmacological Action Expectorants; Disinfectants
Other names Catechol, Methyl; Methyl Catechol; Guaicol; 2-Methoxyphenol; 2-Methoxy-Phenol; 2-Hydroxyanisole; 2-Hydroxy-Anisole
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
zingerone  122-48-5 4-(4- hydroxy-3-methoxyphenyl)-2-butanone  Guaiacol/*analogs & derivatives.  Xenobiotica 6(7):411;1976
dihydroguaiaretic acid  36469-60-0 2,3-dimethyl-1-(3'-methoxy-4'-hydroxyphenyl)-4- (3''-methoxy-4''hydroxyphenyl)butane  *Lignans Guaiacol/*analogs & derivatives.  Pharm Res Comm 9(10):917;1977
metoxibutropate  66332-77-2 Benzeneacetic acid, alpha-methyl-4-(2-methylpropyl)-, 2-methoxyphenyl ester  Guaiacol/*analogs & derivatives Ibuprofen/*analogs & derivatives.  Boll Chim Farm 118(4):232;1979
4-vinylguaiacol  7786-61-0 4-ethenyl-2- methoxyphenol  Guaiacol/*analogs & derivatives.  Science 195(4278):575;1977
yakuchinone- 78954-23-1   Guaiacol/*analogs & derivatives Zingiberaceae.  Planta Med 1984;50(2):186
4-ethylguaiacol  2785-89-9 Phenol, 4-ethyl-2-methoxy  Guaiacol/*analogs & derivatives.  Pharmacology 1993 Nov;47(5):300-8
cinnamophilin  154677-96-0   *Lignans Guaiacol/*analogs & derivatives Thromboxane-A Synthase/antagonists & inhibitors.  Br J Pharmacol 1994 Mar;111(3):906-12
FR dental filling  57017-83-1 FR (dental material)  *Barium Sulfate *Calcium Hydroxide *Formaldehyde *Guaiacol *Zinc Oxide Drug Combinations Root Canal Filling Materials.  Shikwa Gakuho 1980;80(10):1471
6-paradol  27113-22-0   Apoptosis *Ketones Guaiacol/*analogs & derivatives.  Cancer Res 2001 Feb 1;61(3):850-3
gigantol  67884-30-4   Guaiacol/*analogs & derivatives.  Zhongguo Zhong Yao Za Zhi 2002 Dec;27(12):919-23
guaiacolsulfonic acid  50855-43-1   Guaiacol/*analogs & derivatives.  J Pharm Sci 68(1):118;1979; Rev Med Chir Soc Med Nat Iasi 82(1):131;1978; Rev Odontostomatol (Paris) 5(5):345;1976
gingerdione  61871-71-4   Guaiacol/*analogs & derivatives.  Prostaglandins Leukotrienes Med 1986;24(2-3):195
PCG (combination)  78457-01-9 Phenol, 2-methoxy-, mixt. with phenol and 1,1,1-trichloro-2-methyl-2-propanol  *Chlorobutanol *Guaiacol *Phenols Drug Combinations.  Pediatrics 1980;65(3):630
3,4,5-trichloroguaiacol  57057-83-7   Guaiacol/*analogs & derivatives.  Ecotoxicol Environ Safety 1990;20(3):354
4,5,6-trichloroguaiacol  2668-24-8   Guaiacol/*analogs & derivatives.  Ecotoxicol Environ Safety 1990;20(3):354
6-gingesulfonic acid  145937-21-9   *Sulfonic Acids Guaiacol/*analogs & derivatives.  Chem Pharm Bull (Tokyo) 1992 Aug;40(8):2239-41
mimosifoliol  0   *Acrylates Guaiacol/*analogs & derivatives.  J Nat Prod 1996 Feb;59(2):190-2
4,8-bis(4-hydroxy-3-methoxyphenyl)-3,7-dioxabicyclo(3.3.0)octane-2,6-dione  0   *Bicyclo Compounds, Heterocyclic Guaiacol/*analogs & derivatives.  In Vivo 2005 Sep-Oct;19(5):849-53
thioguaiacol  7217-59-6 Benzenethiol, 2-methoxy  Guaiacol/*analogs & derivatives Flavoring Agents.  Food Cosmet Toxicol 1981;19(6):753
2-guaiacolethanol acetylsalicylate  82273-25-4 Benzoic acid, 2-(acetyloxy)-, 2-(2-methoxyphenoxy)ethyl ester  Aspirin/*analogs & derivatives Guaiacol/*analogs & derivatives.  Bell Chim Farm 1982;120(12):730
Codobromyl  126371-24-2   *Codeine *Guaiacol *Hydrocarbons, Brominated Drug Combinations.  Rev Neurol (Paris) 1988;144(5):380
3,4,6-trichloroguaiacol  60712-44-9   Guaiacol/*analogs & derivatives.  Ecotoxicol Environ Safety 1990;20(3):354
guaiacol salicylate  87-16-1   Aspirin/*analogs & derivatives Guaiacol/*analogs & derivatives.  Yao Hsueh Hsueh Pao 1990;25(9):664
4-fluoroguaiacol  450-93-1   Guaiacol/*analogs & derivatives.  Int J Rad Appl Instrum (A) 1991;42(7):673
guaiacol-salsalate  0   *Salicylic Acids Guaiacol/*analogs & derivatives.  Farmaco 1993 Jan;48(1):95-103
1-(4-hydroxy-3-methoxyphenyl)-2-propanone  2503-46-0   Acetone/*analogs & derivatives Guaiacol/*analogs & derivatives Flavoring Agents.  Xenobiotica 1993 Jun;23(6):693-701
dehydroparadol  53172-10-4   Guaiacol/*analogs & derivatives.  Res Comm Chem Pathol Pharmacol 1994 Apr;84(1):53-61
solorinine  160098-90-8 Benzenebutanoic acid, alpha-(dimethylamino)-4-hydroxy-3,5-dimethoxy-, methyl ester, (+)  *Amino Acids Guaiacol/*analogs & derivatives.  Phytochemistry 1994 Nov;37(4):1209-10
graminone B  0   *Furans Guaiacol/*analogs & derivatives.  J Nat Prod 1994 Dec;57(12):1734-6
2,2'-dihydroxy-5,5'-dimethoxybiphenyl-3,3'-dicarbaldehyde  0   *Benzaldehydes Guaiacol/*analogs & derivatives.  Acta Crystallogr C 1999 Jul 15;55( Pt 7):1176-9
3,3'-dimethoxy-4,4'-dihydroxystilbene  0   *Stilbenes Guaiacol/*analogs & derivatives.  Chung Kuo Chung Yao Tsa Chih 1997 Feb;22(2):106-8
1,2-dihydroxy-1-(2',3'-dihydroxy-4'-methoxyphenyl)-2-(3'',4'',5''-trimethoxyphenyl)ethane  0   *Ethylene Glycols Guaiacol/*analogs & derivatives.  J Nat Prod 2000 Jul;63(7):969-74
Shin Ruru A  0   Drugs, Non-Prescription *Acetaminophen *Caffeine *Guaiacol *Muramidase Drug Combinations.  J Dermatol 2000 Jun;27(6):401-4
tetraguaiacol  0   Guaiacol/*analogs & derivatives.  Chemistry 2001 Jun 1;7(11):2449-58
tetrachloroguaiacol  0   Guaiacol/*analogs & derivatives.  Aquat Toxicol 2001 Sep;54(1-2):143-8
2-(3-hydroxy-4-methoxyphenyl)-3-(3,4,5-trimethoxyphenyl)thiophene  0   *Thiophenes Guaiacol/*analogs & derivatives.  Bioorg Med Chem Lett 2001 Sep 3;11(17):2341-3
2-(3-hydroxy-4-methoxyphenyl)-3-((3,4,5-trimethoxyphenyl)carbonyl)thiophene  0   *Thiophenes Guaiacol/*analogs & derivatives.  Bioorg Med Chem Lett 2001 Sep 3;11(17):2341-3
1-hydroxy-2,5-diguaicyl-3,7-dioxabicyclo(3.3.0)octane  0   *Bicyclo Compounds, Heterocyclic Guaiacol/*analogs & derivatives.  Phytochemistry 2002 Jan;59(1):85-90
scaphopetalone  0   *Tetrahydronaphthalenes Guaiacol/*analogs & derivatives.  Phytochemistry 2003 Feb;62(4):647-50
10-hydroxyoleuropein  0   *Glucosides Guaiacol/*analogs & derivatives.  Nat Prod Res 2003 Dec;17(6):381-7
8'-hydroxylariciresinol-4'-O-glucopyranoside  0   *Glucosides Guaiacol/*analogs & derivatives.  Nat Prod Res 2003 Dec;17(6):381-7
4-(1-ethoxy-1-(4-hydroxy-3-methoxy)benzyl)methyl-2-(4-hydroxy-3-methoxy)benzyl-3-hydroxymethyltetrahydrofuran  0   *Furans Guaiacol/*analogs & derivatives.  Yao Xue Xue Bao 2003 Jul;38(7):520-2
2-(3-hydroxy-4-methoxybenzylidene)-1-azabicyclo(2.2.2)octan-3-one  0   *Quinuclidines Guaiacol/*analogs & derivatives.  Acta Crystallogr C 2003 Nov;59(Pt 11):o647-9
(Z)-2-(3-methoxybenzylidene)-1-azabicyclo(2.2.2)octan-3-one  0   *Quinuclidines Guaiacol/*analogs & derivatives.  Acta Crystallogr C 2005 Nov;61(Pt 11):o660-1
4-propylguaiacol  0   Guaiacol/*analogs & derivatives.  J Agric Food Chem. 2006 Apr 19;54(8):3047-54
rourinoside  0   *Glycolipids Guaiacol/*analogs & derivatives.  Phytochemistry 2006 Julu;67(13):1378-84
1-(4-(3-fluoropropoxy)-3-methoxyphenyl)-5-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1,4,6-heptatrien-3-one  0   Fluorine Radioisotopes Guaiacol/*analogs & derivatives.  J Med Chem 2006 Oct 5;49(20):6111-9
pyrrolidinemethyltetracycline guaiacol sulfonate  35054-80-9 Benzenesulfonic acid, hydroxymethoxy-, compd. with (4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha))-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(1-pyrrolidinylmethyl)-2-naphthacenecarboxamide  Guaiacol/analogs & derivatives Rolitetracycline/*analogs & derivatives.  Boll Chim Farm 110(10):605;1972
5-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-phenyl-3- heptanone  0   Guaiacol/*analogs & derivatives.  Yakugaku Zasshi 98(9):1255;1978