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Benzylamines

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Definition: Toluenes in which one hydrogen of the methyl group is substituted by an amino group. Permitted are any substituents on the benzene ring or the amino group.     
Examples Pargyline 		Other names alpha-Aminotoluene; Phenylmethylamine; alpha Aminotoluene
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
(2-(6-fluoro-1H-indol-3-yl)-ethyl)-(3-(2,2,3,3-tetrafluoropropoxy)benzyl)amine  0   *Benzylamines *Indoles Serotonin Antagonists. Int J Neuropsychopharmacol. 2010 Sep;13(8):1021-33.
ciliabrevin  0   *Benzimidazoles *Benzylamines. Cytoskeleton (Hoboken) 2011 Mar;68(3):188-203
(2-fluorobenzyl)-(2-methyl-2-phenyl-2H-chromen-6-yl-amine)  0   *Benzopyrans *Benzylamines Lipoxygenase Inhibitors. Cell Biochem Funct. 2011 Mar;29(2):126-34
2-acetyl benzylamine  0   *Acetophenones *Benzylamines. J Biosci 2010 Dec;35(4):565-70
2-(4-iodo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine  0   *Benzylamines *Phenethylamines Carbon Radioisotopes Ligands Receptor, Serotonin, 5-HT2A. J Nucl Med 2010 Nov;51(11):1763-70
3,4-bis(tetradecyloxy)benzylamine  0   *Benzylamines. Biochem Pharmacol. 2010 Dec 15;80(12):2050-6
2-(2-((2-hydroxybenzyl)amino)ethylamino)-2-(2-hydroxyphenyl)acetic acid  0   *Benzylamines Glycine/*analogs & derivatives. J Agric Food Chem 2010 Jul 14;58(13):7908-14
vetrabutin chlorhydrate  0   *Benzylamines. J Vet Pharmacol ther 2010 Feb;33(1):28-34
PKCz1257.3 compound  0   *Benzylamines *Pyrroles Protein Kinase C/antagonists & inhibitors. Invest New Drugs 2010 Jun;28(3):268-75
1-(benzylamino)ethaniminium  0   *Amidines *Benzylamines Nitric Oxide Synthase Type II/antagonists & inhibitors. J Med Chem 2009 Mar 12;52(5):1481-5
N-tert-butyl isoquine  0   *Aminoquinolines *Benzylamines. J Med Chem 2009 Mar 12;52(5):1408-15
2-(4-((benzylmethylamino)methyl)benzylidene)-6-(5-piperidin-1-yl-pentyloxy)-3,4-dihydro-2H-naphthalen-1-one  0   *Benzylamines *Tetrahydronaphthalenes. Bioorg Med Chem 2010 Mar 1;18(5):1749-60
2-(4-((benzylmethylamino)methyl)benzylidene)-6-(5-diethylaminopentyloxy)-3,4-dihydro-2H-naphthalen-1-one  0   *Benzylamines *Tetrahydronaphthalenes. Bioorg Med Chem 2010 Mar 1;18(5):1749-60
3-(triphenylmethylaminomethyl)pyridine  0   *Benzylamines *Pyridines. Mol Pharmacol 2006 Nov;70(5):1494-502
SBE13 compound  0   *Benzylamines *Pyridines. ChemMedChem2009 Nov;4(11):1806-9
(5-(2-((benzoyloxycarbonylethylamino)methyl)-4-trifluoromethylphenyl)pyridin-3-yl)acetic acid  0   *Benzylamines Niacin/*analogs & derivatives. J Pharmacol Exp Ther 2010 Mar;332(3):764-75
(2'-((cyclopropanecarbonylethylamino)methyl)-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl)acetic acid  0   *Benzylamines. J Pharmacol Exp Ther 2010 Mar;332(3):764-75
N,N-bis(diphenylphosphino)-N-((S)-alpha-methylbenzyl)amine  0   *Benzylamines. J Phys Chem A. 2009 May 21;113(20):5993-7
quinpramine  0   *Acridines *Benzylamines. Exp Neurol 2009 Jun;217(2):240-1
N,N-dipropyl-N'-(4-((((1H-imidazol-2-yl)methyl)((1-methyl-1H-imidazol-2-yl) methyl)amino)methyl)benzyl)-N'-methylbutane-1,4-diamine  0   *Benzylamines *Imidazoles. Cancer Sci 2009 Apr;100(4):778-81
bis(2-pyridylmethyl)benzylamine  0   *Benzylamines *Pyridines. Spectrochim Acta A Mol Biomol Spectrosc. 2009 Jul;73(1):20-4
triphenylmethylamine  0   *Benzylamines *Trityl Compounds. Acta Crystallogr C 2009 Feb;65(Pt 2):o31-4
1-(1H-1,2,4-triazole)-2-(2,4-difluorophenyl)-3-(N-methyl-N-(4-iodobenzyl)amino)-2-propanol  0   *Benzylamines *Triazoles. J Chromatogr B Analyt Technol Biomed Life Sci 2009 Feb 1;877(4):382-6
1-(isopropylamino)-3-(5-((isopropylamino)methyl)-2-methoxyphenoxy)propan-2-ol  0   *Benzylamines *Propanolamines. J Pharm Pharmacol 2008 Nov;60(11):1501-6
alpha-amino phenylalanine tetrazole  0   *Benzylamines *Tetrazoles. J Sep Sci 2008 Sep;31(16-17):3002-8
N,N-dimethyl-2-(2'-amino-4'-hydroxymethylphenylthio)-5-iodobenzylamine  0   *Benzylamines *Sulfides Carbon Radioisotopes. J Med Chem 2008 Jan 24;51(2):271-81
N,N-dimethyl-2-(2'-amino-4'-hydroxymethylphenylthio)-5-bromobenzylamine  0   *Benzylamines *Sulfides Carbon Radioisotopes. J Med Chem 2008 Jan 24;51(2):271-81
N,N-dimethyl-2-(2'-amino-4'-hydroxymethylphenylthio)-5-fluorobenzylamine  0   *Benzylamines *Sulfides Carbon Radioisotopes. J Med Chem 2008 Jan 24;51(2):271-81
2-(N,N-dibenzylamino)butane-1,3-diol  0   *Benzylamines *Butylene Glycols. Acta Crystallogr C 2008 Jan;64(Pt 1):o18-20
N,N'-di-2-pyridinyl-1,4-benzenedimethanamine  0   *Aminopyridines *Benzylamines Receptors, CXCR4/antagonists & inhibitors. J Med Chem 2007 Nov 15;50(23):5655-64
bis(5-tert-butyl-2-hydroxy-3-methylbenzyl)(6-hydroxyhexyl)amine  0   *Benzylamines. Acta Crystallogr C 2007 Jul;63(Pt 7):o386-8
dapoxetine-N-oxide  0   *Benzylamines *Naphthalenes. J Clin Pharmacol 2007 Mar;47(3):315-22
N-((2,2-dimethyl-2,3-dihydro-benzofuran-7-yloxy)ethyl)-3-(cyclopent-1-enyl)-benzylamine  0   *Benzofurans *Benzylamines *Cyclopentanes. Naunyn Schmiedebergs Arch Pharmacol. 2007 Jun;375(4):241-50
1-(tert-butylamino)-3-(5-tert-butylaminomethyl-2-methoxyphenoxy)propan-2-ol  0   *Benzylamines *Propanolamines Receptors, Adrenergic, beta. J Pharm Pharmacol 2007 Mar;59(3):429-36
N-(2-benzyl),N-(1-methylpyrrol-2-ylmethyl)amine  0   *Benzylamines *Pyrroles Monoamine Oxidase. J Med Chem 2007 Mar 8;50(5):922-31
N-methyl,N-(benzyl),N-(pyrrol-2-ylmethyl)amine  0   *Benzylamines *Pyrroles Monoamine Oxidase. J Med Chem 2007 Mar 8;50(5):922-31
N-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yloxy)ethyl)-3-(cyclopent-1-enyl)benzylamine  0   *Benzofurans *Benzylamines Receptors, Dopamine D2/antagonists & inhibitors Receptor, Serotonin, 5-HT1A/agonists. J Med Chem 2007 Feb 22;50(4):865-76
C,N-diphenylnitrone  0   *Aniline Compounds *Benzylamines. J Org Chem 2006 Dec 22;71(26):9831-40
N-(2-bromophenyl)-2-(4,6-dimethoxypyrimidin-2-yloxy)benzylamine  0   *Benzylamines *Pyrimidines. J Agric Food Chem. 2006 Aug 9;54(16):5954-7
trans-(6-benzhydryl-tetrahydropyran-3-yl)-benzylamine  0   *Benzylamines *Pyrans. Bioorg Med Chem. 2006 Jun 1;14(11):3953-66
N,N-dimethyl-2-(2'-amino-4'-hydroxymethylphenylthio)benzylamine  0   *Benzylamines. Nucl Med Biol. 2005 Apr;32(3):211-24
(4-(4-((benzyl(2-methyl-3-((methylsulfonyl)amino)phenyl)amino)methyl)phenoxy)phenoxy)acetic acid  0   *Benzylamines *Sulfonamides. J Med Chem 2005 Aug 11;48(16):5295-304
(5-(4-(((2,4-difluorobenzyl)(2-methyl-3-((methylsulfonyl)amino)phenyl)amino)methyl)phenoxy)-2-fluorophenoxy)acetic acid  0   *Benzylamines *Sulfonamides. J Med Chem 2005 Aug 11;48(16):5295-304
Akt-I-1,2 compound  0   *Benzylamines *Quinoxalines. Biochem J 2005 Jan 15;385(Pt 2):399-408
3-(1-dimethylaminoethyl)phenol  0   *Benzylamines *Phenols. Biomed Chromatogr 2004 Apr;18(3):160-6
2-(2-(dimethylaminomethyl)benzyl)-5-iodophenylamine  0   *Aniline Compounds *Benzylamines Iodine Radioisotopes. J Med Chem 2004 Oct 7;47(21):5258-64
N,N'-dibenzyl-1,10-diaminodecane  0   *Benzylamines. Pest Manag Sci 2004 Feb;60(2):143-8
4-hydroxy 3-methoxybenzylamine  0   *Benzylamines. Eur J Mass Spectrom (Chichester, Eng) 2003;9(4):351-60
A 228839  0   *Benzylamines Methionine/*analogs & derivatives. Drug News Perspect 2003 Jun;16(5):332-6
tribenzylamine  620-40-6   *Benzylamines. Z Naturforsch (C) 2003 Sep-Oct;58(9-10):640-2
N,N-dimethyl-2-(2-amino-4-fluorophenylthio)benzylamine  0   *Benzylamines. Appl Radiat Isot 2003 Feb;58(2):183-91
AP 2238  0   *Benzylamines *Coumarins Acetylcholinesterase/antagonists & inhibitors. J Med Chem 2003 Jun 5;46(12):2279-82
GW 3965  0   *Benzylamines *Benzoic Acids Ligands. J Med Chem 2002 May 9;45(10):1963-6
N,N-dimethyl-2-(2-amino-4-methylphenylthio)benzylamine  0   *Benzylamines Carbon Radioisotopes Ligands. J Pharmacol Exp Ther 2003 Jan;304(1):81-7
2-((2-amino-4-chloro-5-fluorophenyl)thio)-N,N-dimethylbenzenemethanamine  0   *Benzylamines *Sulfides Fluorine Radioisotopes. J Med Chem 2002 Oct 10;45(21):4716-23
1-amino-3',4'-dichlorobenzylphosphonic acid  0   *Benzylamines *Phosphonic Acids Phenylalanine Ammonia-Lyase/antagonists & inhibitors. Phytochemistry 2002 Jan;59(1):9-21
FR 194738  0   *Benzylamines. Eur J Pharmacol 2001 Nov 9;431(1):11-6
tris(2-hydroxy-3,5-dimethylbenzyl)amine  0   *Benzylamines *Cresols. Anal Sci 2001 Jul;17(7):913-4
N-(3-(4-morpholino)propyl)-N-methyl-2-hydroxy-5-iodo-3-methylbenzylamine  0   *Benzylamines *Morpholines. Eur J Nucl Med 2001 Apr;28(4):408-17
4,5-dimethoxy-2-mercaptobenzylamine  0   *Benzylamines *Sulfhydryl Compounds. Org Lett 2001 May 3;3(9):1403-5
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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