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Benzofurans

More information in Books or onNLM PubMed
Definition: Compounds that contain a BENZENE ring fused to a furan ring.     
Examples Amiodarone; Benzbromarone; Cantharidin; Citalopram; Fura-2; Griseofulvin; Pterocarpans 		Other names Coumarones; Diphenylbenzofuran
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
5-(6-dimethylamino-2-methyl-3-oxo-2,3-dihydro-benzofuran-2-yl)-4-methyl-penta-2,4-dienoic acid hydroxamide  0   *Benzofurans Histone Deacetylase Inhibitors. Curr Cancer Drug Targets. 2011 Oct;11(8):919-28
4-acetyl-5-hydroxy-3,6,7-trimethylbenzofuran-2(3H)-one  0   *Benzofurans. Nat Prod Commun. 2011 Dec;6(12):1913-4
8-deisopropyladunctin B  0   *Benzofurans. Chem Pharm Bull (Tokyo). 2012;60(1):94-103
flavimycin B  0   *Benzofurans. J Nat Prod. 2012 Feb 24;75(2):271-4
flavimycin A  0   *Benzofurans. J Nat Prod. 2012 Feb 24;75(2):271-4
ERG7.153  0   *Piperazines *Benzofurans. Chem Biol. 2011 Oct 28;18(10):1273-83.
N-methoxy rocaglamide  0   *Benzofurans. J Med Chem. 2012 Jan 12;55(1):558-62.
morusyunnansin B  0   *Benzofurans. J Nat Prod. 2012 Jan 27;75(1):82-7
morusyunnansin A  0   *Benzofurans. J Nat Prod. 2012 Jan 27;75(1):82-7
CCF 06240  0   *Benzofurans *Phenylpropionates Protein Tyrosine Phosphatase, Non-Receptor Type 1/antagonists & inhibitors. Mol Cell Biochem. 2011 Nov;357(1-2):65-72.
2-(3,4-dimethoxyphenyl)-5-(3-methoxypropyl)benzofuran  0   *Benzofurans. J Pharmacokinet Pharmacodyn. 2011 Oct;38(5):637-51
2 3-cis-6-acetyl-5-hydroxy-2-(hydroxymethylvinyl)-2,3-dihydrobenzofuran-3-ol angelate  0   *Benzofurans. Yao Xue Xue Bao. 2010 Jan;45(1):82-6
mulberrofuran F1  0   *Benzofurans Antineoplastic Agents, Phytogenic. Yao Xue Xue Bao. 2010 Jan;45(1):77-81
2-methyl-5-(3-(4-(methylsulfinyl)phenyl)-1-benzofuran-5-yl)-1,3,4-oxadiazole  0   *Benzofurans *Oxadiazoles Glycogen Synthase Kinase 3/antagonists & inhibitors. J Neurochem. 2011 Dec;119(6):1330-40.
(5-amino-3-methyl-6-methoxybenzo(b)furan-2-yl)(3,4,5-trimethoxyphenyl) methanone  0   *Anisoles *Benzofurans. ChemMedChem. 2011 Oct 4;6(10):1841-53.
7-hydroxy-5-methoxy-4,6-dimethyl-7-O-alpha-L-rhamnosyl-phthalide  0   *Benzofurans *Glycosides. J Asian Nat Prod Res. 2011 Dec;13(12):1069-73
7-hydroxy-5-methoxy-4,6-dimethyl-7-O-beta-D-glucopyranosyl-phthalide  0   *Benzofurans *Glycosides. J Asian Nat Prod Res. 2011 Dec;13(12):1069-73
1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-3-oxo-1,3-dihydroisobenzofuran-5-carbonitrile  0   *Benzofurans Phospholipases A2/antagonists & inhibitors. Basic Clin Pharmacol Toxicol. 2011 Oct;109(4):292-9.
alphitonin  0   *Benzofurans. J Nat Prod. 2011 Oct 28;74(10):2243-9
7-demethoxyegonol-9(Z),12(Z) linoleate  0   *Benzofurans. J Nat Prod. 2011 Oct 28;74(10):2081-8
egonol-9(Z),12(Z) linoleate  0   *Benzofurans. J Nat Prod. 2011 Oct 28;74(10):2081-8
7-demethoxyegonol oleate  0   *Benzofurans. J Nat Prod. 2011 Oct 28;74(10):2081-8
ganodone  0   *Benzofurans Antineoplastic Agents. J Nat Prod. 2011 Oct 28;74(10):2045-51
BNC 105P  0   *Benzofurans *Phosphoric Acid Esters. Clin Cancer Res. 2011 Aug 1;17(15):5152-60.
moracin M  0   *Benzofurans *Resorcinols. Org Lett. 2011 Sep 16;13(18):4846-9
PF 00337210  0   *Benzofurans *Quinolines Receptors, Vascular Endothelial Growth Factor/antagonists & inhibitors. AAPS PharmSciTech 2011 Mar;12(1):362-71
2-(2-hydroxy-4-methoxyphenyl)-5-(3-hydroxypropyl)benzofuran  0   *Benzofurans Anti-Inflammatory Agents, Non-Steroidal. J Nat Prod. 2011 Aug 26;74(8):1779-86
(4-(dimethylamino)phenyl)(5-iodobenzofuran-2-yl)methanone  0   *Aniline Compounds *Benzofurans Ligands. Bioorg Med Chem 2011 Jul 1;19(13):4148-53
picrasmalignan A  0   *Benzofurans. Chem Biodivers 2011 Jun;8(6):1163-9
5-bromo-2-(4-chlorobenzoyl)-(Z)-3-(2-cyano-3-hydroxybut-2-enonyl)aminobenzo(b)furan  0   *Benzofurans Selective Estrogen Receptor Modulators. Pharmacol Sci. 2011;116(2):214-20
(E)-2-(hept-1-enyl)-3-(hydroxymethyl)-5-(3-methylbut-2-enyl)benzene-1,4-diol  0   *Benzofurans. J Nat Prod. 2011 Jul 22;74(7):1636-9
(E)-4-(hept-1-enyl)-7-(3-methylbut-2-enyl)-2,3-dihydrobenzofuran-2,5-diol  0   *Benzofurans. J Nat Prod. 2011 Jul 22;74(7):1636-9
2-((3,5-dihydroxy)-(Z)-4-(3-methylbut-1-enyl)phenyl)benzofuran-ol  0   *Benzofurans. BMC Complement Altern Med. 2011;11() (dup#47):42
3-(2-(dimethylamino)isopropoxy)-1-hydroxybenzo(b)naphtho(2,3-d)furan-6,11-dione  0   *Benzofurans *Naphthoquinones. Chem Biol Interact 2011 Aug 15;193(1):43-9
filifolinol acetate  0   *Benzofurans *Spiro Compounds. Nat Prod Commun. 2011 Jun;6(6):759-62
3,5-dimethyl-7H-furo(3,2-g)chromen-7-one  0   *Benzofurans *Coumarins. Chemotherapy 2011;57(2):162-72
2-(4'-hydroxybenzoyl)-5,6-methylenedioxy-benzofuran  0   *Benzofurans. Fitoterapia. 2011 Mar;82(2):190-2
2-(4'-hydroxybenzyl)-5,6-methylenedioxybenzofuran  0   *Benzofurans. Fitoterapia. 2011 Mar;82(2):190-2
N-(2-(7-(cyclohexylmethyl)-1,6-dihydro-2H-indeno(5,4-b)furan-8-yl)ethyl)acetamide  0   *Acetamides *Benzofurans Receptors, Melatonin/agonists. J Med Chem 2011 May 12;54(9):3436-44
aperidine  0   *Benzofurans *Guanidines. Org Lett. 2011 May 20;13(10):2789-91
5,7-ditert-butyl-3-(3,4-dimethylphenyl)benzofuran-2(3H)-one  0   *Benzofurans. J Phys Chem B. 2011 Apr 7;115(13):3588-603
N-(5-(2-bromobenzyl)thiazole-2-yl)benzofuran-2-carboxamide  0   *Benzofurans *Thiazoles. Cancer Lett 2011 Jul 28;306(2):190-6
DA 8031  0   *Benzofurans Serotonin Uptake Inhibitors. Urology 2011 Apr;77(4):1006.e17-21
diphosphin 4,6-bis(3-diisopropylphosphinophenyl)dibenzofuran  0   *Benzofurans Ligands. Inorg Chem. 2011 Mar 21;50(6):2545-52
deuteromycol B  0   *Benzofurans. Arch Pharm Res. 2010 Nov;33(11):1729-33
deuteromycol A  0   *Benzofurans. Arch Pharm Res. 2010 Nov;33(11):1729-33
1'-benzyl-3-(2-fluoroethyl)-3H-spiro((2)benzofuran-1,4'-piperidine)  0   *Piperidines *Benzofurans Fluorine Radioisotopes Ligands. Eur J Nucl Med Mol Imaging 2011 Mar;38(3):540-51
N-(2-(dimethylamino)ethyl)-2-(3-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)phenoxy)acetamide  0   *Benzofurans *Ethylamines. J Surg Oncol 2011 Apr;103(5):442-50
3-(((6-methoxy-10-methyl-1H,3H-benzo(h)furo(4,3,2-de)-2-benzopyran-1-yl)oxy)methyl)-5-methylnaphtho(2,3-b)furan-4,9-dione  0   *Benzofurans *Naphthoquinones. J Med Food 2011 Jan-Feb;14(1-2):120-7
N-((1-((5-(4-fluorophenyl)-2-methyl-4-thiazolyl)carbonyl)-2-piperidinyl)methyl)-4-benzofurancarboxamide  0   *Benzofurans *Thiazoles Carbon Radioisotopes. Drug Metab Dispos 2011 Feb;39(2):215-27
loxophlebal A  0   *Benzofurans Phloroglucinol/*analogs & derivatives. Fitoterapia. 2010 Oct;81(7):878-83
TAK-875  0   *Benzofurans *Sulfones. Drug News Perspect. 2010 Dec;23(10):667
wittifuran  0   *Benzofurans. Fitoterapia. 2010 Oct;81(7):742-6
3-carboxyethyl-phthalide  0   *Benzofurans. Fitoterapia. 2010 Dec;81(8):1088-90
mono-4-(N-6-deoxy-6-amino-beta-cyclodextrin)-7-nitrobenzofuran  0   *Benzofurans *Cyclodextrins. Int J Pharm. 2011 Jan 17;403(1-2):15-22
N-(4-benzoylphenyl)benzofuran-2-carboxamide  0   *Benzofurans. J Enzyme Inhib Med Chem. 2010 Dec;25(6):751-5
N-(9,10-dihydro-9,10-dioxoanthracen-2-yl)benzofuran-2-carboxamide  0   *Anthracenes *Benzofurans. J Enzyme Inhib Med Chem. 2010 Dec;25(6):751-5
gamma-2-viniferin  0   *Benzofurans. Arch Pharm Res 2010 Oct;33(10):1655-64
rubropunctatin  0   *Benzofurans *Benzopyrans. Appl Microbiol Biotechnol 2010 Nov;88(5):1169-77
stemofuran L  0   *Benzofurans. J Nat Prod. 2010 Nov 29;73(11):1833-8
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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