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Benzofurans
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Definition
: Compounds that contain a BENZENE ring fused to a furan ring.
Examples
Amiodarone
;
Benzbromarone
;
Cantharidin
;
Citalopram
;
Fura-2
;
Griseofulvin
;
Pterocarpans
Other names
Coumarones; Diphenylbenzofuran
Substance
CAS Registry & name
Categories
Source
Drugs
*
5-
(6-
dimethylamino-
2-
methyl-
3-
oxo-
2,3-
dihydro-
benzofuran-
2-
yl)-
4-
methyl-
penta-
2,4-
dienoic acid hydroxamide
0
*Benzofurans
Histone Deacetylase Inhibitors.
Curr Cancer Drug Targets. 2011 Oct;11(8):919-28
4-
acetyl-
5-
hydroxy-
3,6,7-
trimethylbenzofuran-
2(3H)-
one
0
*Benzofurans.
Nat Prod Commun. 2011 Dec;6(12):1913-4
8-
deisopropyladunctin B
0
*Benzofurans.
Chem Pharm Bull (Tokyo). 2012;60(1):94-103
flavimycin B
0
*Benzofurans.
J Nat Prod. 2012 Feb 24;75(2):271-4
flavimycin A
0
*Benzofurans.
J Nat Prod. 2012 Feb 24;75(2):271-4
ERG7.153
0
*Piperazines
*Benzofurans.
Chem Biol. 2011 Oct 28;18(10):1273-83.
N-
methoxy rocaglamide
0
*Benzofurans.
J Med Chem. 2012 Jan 12;55(1):558-62.
morusyunnansin B
0
*Benzofurans.
J Nat Prod. 2012 Jan 27;75(1):82-7
morusyunnansin A
0
*Benzofurans.
J Nat Prod. 2012 Jan 27;75(1):82-7
CCF 06240
0
*Benzofurans
*Phenylpropionates
Protein Tyrosine Phosphatase, Non-Receptor Type 1/antagonists & inhibitors.
Mol Cell Biochem. 2011 Nov;357(1-2):65-72.
2-
(3,4-
dimethoxyphenyl)-
5-
(3-
methoxypropyl)benzofuran
0
*Benzofurans.
J Pharmacokinet Pharmacodyn. 2011 Oct;38(5):637-51
2 3-
cis-
6-
acetyl-
5-
hydroxy-
2-
(hydroxymethylvinyl)-
2,3-
dihydrobenzofuran-
3-
ol angelate
0
*Benzofurans.
Yao Xue Xue Bao. 2010 Jan;45(1):82-6
mulberrofuran F1
0
*Benzofurans
Antineoplastic Agents, Phytogenic.
Yao Xue Xue Bao. 2010 Jan;45(1):77-81
2-
methyl-
5-
(3-
(4-
(methylsulfinyl)phenyl)-
1-
benzofuran-
5-
yl)-
1,3,4-
oxadiazole
0
*Benzofurans
*Oxadiazoles
Glycogen Synthase Kinase 3/antagonists & inhibitors.
J Neurochem. 2011 Dec;119(6):1330-40.
(5-
amino-
3-
methyl-
6-
methoxybenzo(b)furan-
2-
yl)(3,4,5-
trimethoxyphenyl) methanone
0
*Anisoles
*Benzofurans.
ChemMedChem. 2011 Oct 4;6(10):1841-53.
7-
hydroxy-
5-
methoxy-
4,6-
dimethyl-
7-
O-
alpha-
L-
rhamnosyl-
phthalide
0
*Benzofurans
*Glycosides.
J Asian Nat Prod Res. 2011 Dec;13(12):1069-73
7-
hydroxy-
5-
methoxy-
4,6-
dimethyl-
7-
O-
beta-
D-
glucopyranosyl-
phthalide
0
*Benzofurans
*Glycosides.
J Asian Nat Prod Res. 2011 Dec;13(12):1069-73
1-
(3-
dimethylaminopropyl)-
1-
(4-
fluorophenyl)-
3-
oxo-
1,3-
dihydroisobenzofuran-
5-
carbonitrile
0
*Benzofurans
Phospholipases A2/antagonists & inhibitors.
Basic Clin Pharmacol Toxicol. 2011 Oct;109(4):292-9.
alphitonin
0
*Benzofurans.
J Nat Prod. 2011 Oct 28;74(10):2243-9
7-
demethoxyegonol-
9(Z),12(Z) linoleate
0
*Benzofurans.
J Nat Prod. 2011 Oct 28;74(10):2081-8
egonol-
9(Z),12(Z) linoleate
0
*Benzofurans.
J Nat Prod. 2011 Oct 28;74(10):2081-8
7-
demethoxyegonol oleate
0
*Benzofurans.
J Nat Prod. 2011 Oct 28;74(10):2081-8
ganodone
0
*Benzofurans
Antineoplastic Agents.
J Nat Prod. 2011 Oct 28;74(10):2045-51
BNC 105P
0
*Benzofurans
*Phosphoric Acid Esters.
Clin Cancer Res. 2011 Aug 1;17(15):5152-60.
moracin M
0
*Benzofurans
*Resorcinols.
Org Lett. 2011 Sep 16;13(18):4846-9
PF 00337210
0
*Benzofurans
*Quinolines
Receptors, Vascular Endothelial Growth Factor/antagonists & inhibitors.
AAPS PharmSciTech 2011 Mar;12(1):362-71
2-
(2-
hydroxy-
4-
methoxyphenyl)-
5-
(3-
hydroxypropyl)benzofuran
0
*Benzofurans
Anti-Inflammatory Agents, Non-Steroidal.
J Nat Prod. 2011 Aug 26;74(8):1779-86
(4-
(dimethylamino)phenyl)(5-
iodobenzofuran-
2-
yl)methanone
0
*Aniline Compounds
*Benzofurans
Ligands.
Bioorg Med Chem 2011 Jul 1;19(13):4148-53
picrasmalignan A
0
*Benzofurans.
Chem Biodivers 2011 Jun;8(6):1163-9
5-
bromo-
2-
(4-
chlorobenzoyl)-
(Z)-
3-
(2-
cyano-
3-
hydroxybut-
2-
enonyl)aminobenzo(b)furan
0
*Benzofurans
Selective Estrogen Receptor Modulators.
Pharmacol Sci. 2011;116(2):214-20
(E)-
2-
(hept-
1-
enyl)-
3-
(hydroxymethyl)-
5-
(3-
methylbut-
2-
enyl)benzene-
1,4-
diol
0
*Benzofurans.
J Nat Prod. 2011 Jul 22;74(7):1636-9
(E)-
4-
(hept-
1-
enyl)-
7-
(3-
methylbut-
2-
enyl)-
2,3-
dihydrobenzofuran-
2,5-
diol
0
*Benzofurans.
J Nat Prod. 2011 Jul 22;74(7):1636-9
2-
((3,5-
dihydroxy)-
(Z)-
4-
(3-
methylbut-
1-
enyl)phenyl)benzofuran-
ol
0
*Benzofurans.
BMC Complement Altern Med. 2011;11() (dup#47):42
3-
(2-
(dimethylamino)isopropoxy)-
1-
hydroxybenzo(b)naphtho(2,3-
d)furan-
6,11-
dione
0
*Benzofurans
*Naphthoquinones.
Chem Biol Interact 2011 Aug 15;193(1):43-9
filifolinol acetate
0
*Benzofurans
*Spiro Compounds.
Nat Prod Commun. 2011 Jun;6(6):759-62
3,5-
dimethyl-
7H-
furo(3,2-
g)chromen-
7-
one
0
*Benzofurans
*Coumarins.
Chemotherapy 2011;57(2):162-72
2-
(4'-
hydroxybenzoyl)-
5,6-
methylenedioxy-
benzofuran
0
*Benzofurans.
Fitoterapia. 2011 Mar;82(2):190-2
2-
(4'-
hydroxybenzyl)-
5,6-
methylenedioxybenzofuran
0
*Benzofurans.
Fitoterapia. 2011 Mar;82(2):190-2
N-
(2-
(7-
(cyclohexylmethyl)-
1,6-
dihydro-
2H-
indeno(5,4-
b)furan-
8-
yl)ethyl)acetamide
0
*Acetamides
*Benzofurans
Receptors, Melatonin/agonists.
J Med Chem 2011 May 12;54(9):3436-44
aperidine
0
*Benzofurans
*Guanidines.
Org Lett. 2011 May 20;13(10):2789-91
5,7-
ditert-
butyl-
3-
(3,4-
dimethylphenyl)benzofuran-
2(3H)-
one
0