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Enzyme Precursors
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Definition
: Physiologically inactive substances that can be converted to active enzymes.
IM; coord with specific enzyme (IM); zymogen granules: index under ZYMOGEN GRANULES see SECRETORY VESICLES (IM) + ENZYME PRECURSORS (IM) + specific enzyme (IM)
Examples
Chymotrypsinogen
;
Complement Factor B
;
Pepsinogens
;
Plasminogen
;
Protein C
;
Prothrombin
;
Trypsinogen
Other names
Zymogens; Proenzymes; Precursors, Enzyme
Substance
CAS Registry & name
Categories
Source
Drugs
*
HppA protein, Helicobacter pylori
EC 3.1.3.2
*Acid Phosphatase
*Enzyme Precursors.
FEBS Lett 2002 Aug 14;525(1-3):39-42
His-
S-
SStp protein, Pisum sativum
0
*Enzyme Precursors
*Plant Proteins
*Recombinant Proteins
Ribulose-Bisphosphate Carboxylase.
Plant J 2001 Feb;25(3):349-63
preinvertase
EC 3.2.1.-
*Enzyme Precursors
*beta-Fructofuranosidase.
J Biol Chem 2001 Jan 26;276(4):2411-6
pronapsin
EC 3.4.23.-
*Enzyme Precursors
*Aspartic Acid Endopeptidases.
Eur J Biochem 2000 Dec;267(23):6921-30
aureusidin synthase precursor
EC 1.10.3.-
*Enzyme Precursors
*Mixed Function Oxygenases.
Science 2000 Nov 10;290(5494):1163-6
pre-
ornithine transcarbamoylase
EC 2.1.3.-
*Enzyme Precursors
*Ornithine Carbamoyltransferase.
Mol Cell Biol 2000 Oct;20(19):7205-13
protelomerase protein, Bacteriophage N15
EC 2.7.7.-
*Enzyme Precursors
*Viral Proteins
*Telomerase.
Proc Natl Acad Sci U S A 2000 Jul 5;97(14):7721-6
pro-
matrix metalloproteinase 9
EC 3.4.24.-
*Enzyme Precursors
*Matrix Metalloproteinase 9.
Ann N Y Acad Sci 1999 Jun 30;878:372-87
proplasmepsin II
EC 3.4.23.-
*Enzyme Precursors
*Aspartic Acid Endopeptidases.
Nat Struct Biol 1999 Jan;6(1):32-7
procardosin A
EC 3.4.23.-
*Enzyme Precursors
*Aspartic Acid Endopeptidases
Glycoproteins
Plant Proteins.
Eur J Biochem 1998 Jul 1;255(1):133-8
Boophilus yolk pro-
cathepsin
EC 3.4.23.-
*Enzyme Precursors
*Aspartic Acid Endopeptidases.
Parasitology 1998 Jun;116( Pt 6):525-32
proprotein convertase PC7
EC 3.4.21.-
*Subtilisins
Enzyme Precursors.
J Biol Chem 1997 Aug 8;272(32):19672-81
profollipsin
EC 3.4.24.-
*Enzyme Precursors
*Serine Endopeptidases.
Eur J Biochem 1997 Apr 15;245(2):392-7
procathepsin K, Ser(139)-
Ala(163)
0
*Cathepsins
*Enzyme Precursors.
J Biol Chem 1997 May 23;272(21):13955-60
procaricain
EC 3.4.22.-
*Cysteine Endopeptidases
*Enzyme Precursors
Plant Proteins.
Structure 1996 Oct 15;4(10):1193-203
promatrilysin
EC 3.4.24.-
*Enzyme Precursors
*Metalloendopeptidases.
Clin Chim Acta 1996 Jan 31;244(2):181-98
pre-
ferredoxin-
NADP-
oxidoreductase
EC 1.18.1.-
*Enzyme Precursors
*Ferredoxin-NADP Reductase.
FEBS Lett 1996 Feb 26;381(1-2):153-5
mu-
calpain proenzyme
EC 3.4.22.-
*Calpain
*Enzyme Precursors.
Brain Res 1995 Oct 30;697(1-2):179-86
EapB protein, Cryphonectria parasitica
EC 3.4.23.-
*Enzyme Precursors
*Fungal Proteins
*Aspartic Acid Endopeptidases.
Mol Gen Genet 1996 Jan;250(1):97-105
pro-
lactase-
phlorizin hydrolase
0
*Enzyme Precursors
*Glycosylceramidase.
J Biol Chem 1995 Oct 27;270(43):25722-8
preprocathepsin C
EC 3.4.22.-
*Cathepsins
*Enzyme Precursors.
FEBS Lett 1995 Aug 7;369(2-3):326-30
procarboxypeptidase E
EC 3.4.17.-
*Carboxypeptidases
*Enzyme Precursors.
J Neurochem 1995 Jul;65(1):444-53
procathepsin G
EC 3.4.-
*Enzyme Precursors
*Cathepsin G.
J Biol Chem 1995 May 26;270(21):12912-8
prophospholipase A2
EC 3.1.1.4
*Enzyme Precursors
*Phospholipases A2.
Biochem Biophys Res Commun 1994 Jan 14;198(1):10-5
coagulation factor B, horseshoe crab
EC 3.4.21.-
*Enzyme Precursors
*Serine Endopeptidases
Blood Coagulation Factors
Horseshoe Crabs.
J Biol Chem 1993 Oct 5;268(28):21384-8
proendoproteinase B
EC 3.4.22.-
*Cysteine Endopeptidases
*Enzyme Precursors.
Plant Cell 1992 Mar;4(3):307-18
proaleurain
EC 3.4.22.-
*Cysteine Endopeptidases
*Enzyme Precursors.
Plant Cell 1992 Mar;4(3):307-18
sex-
influenced esterase
EC 3.1.1.-
*Carboxylic Ester Hydrolases
Enzyme Precursors.
Biochem Genet 1991;29(5-6):261
propapain
EC 3.4.22.-
*Enzyme Precursors
*Papain.
J Biol Chem 1991;266(32):21451
preprocolipase
0
*Colipases
*Enzyme Precursors.
Pancrease 1991;6(2):157
progelatinase
EC 3.4.24.-
*Enzyme Precursors
*Gelatinases.
J Biol Chem 1991;266(20):13064
rhizopuspepsinogen
EC 3.4.23.-
*Enzyme Precursors
*Aspartic Acid Endopeptidases
Recombinant Proteins.
J Biol Chem 1991;266(18):11718
procathepsin E
EC 3.4.23.-
*Enzyme Precursors
*Cathepsin E.
Biochem Biophys Res Commun 1991;175(1):152
saruplase
99149-95-8
*Urokinase-Type Plasminogen Activator
Recombinant Proteins
Enzyme Precursors.
Pharma Action
Fibrinolytic Agents
Arzneimittelforschung 1990;40(10):1180
procathepsin L
EC 3.4.22.-
*Enzyme Precursors
*Cathepsin L.
Biochem Biophys Res Commun 1990;168(2):520
preproacrosin
EC 3.4.21.-
*Acrosin
*Enzyme Precursors.
Hum Genet 1989;84(1):59
preprocathepsin H
EC 3.4.22.-
*Cathepsins
*Enzyme Precursors.
Nucleic Acids Res 1989;17(22):9471
preprocarboxypeptidase H
EC 3.4.17.-
*Carboxypeptidases
*Enzyme Precursors.
J Biol Chem 1989;264(10):5988
prepro-
alpha-
lytic protease
EC 3.4.21.-
*Enzyme Precursors
*Serine Endopeptidases.
J Bacteriol 1989;171(3):1320
procathepsin D
EC 3.4.23.-
*Cathepsin D
*Enzyme Precursors.
Biochimie 1988;70(7):943
procathepsin B
EC 3.4.22.-
*Cathepsin B
*Enzyme Precursors.
Biol Chem Hoppe Seyler 1988;369 Suppl:163
preprocathepsin B
EC 3.4.22.-
*Cathepsins
*Enzyme Precursors.
Biol Chem Hoppe Seyler 1988;369 Suppl:163
Limulus clotting factor C
EC 3.4.21.84
*Enzyme Precursors
*Serine Endopeptidases
*Arthropod Proteins.
Eur J Biochem 1988;176(1):89
prosubtilisin
117444-15-2
*Enzyme Precursors
*Peptide Fragments
*Subtilisins.
J Biol Chem 1988;263(26):12959
procarboxypeptidase A-
S6
0
*Enzyme Precursors
*Multienzyme Complexes.
FEBS Lett 1988;232(1):91
preprocathepsin L
EC 3.4.22.-
*Cathepsins
*Enzyme Precursors.
J Clin Invest 1988;81(5):1621
prokallikrein, tissue
EC 3.4.21.-
*Enzyme Precursors
*Kallikreins.
preornithine carbamoyltransferase
EC 2.1.3.-
*Enzyme Precursors
*Ornithine Carbamoyltransferase.
J Cell Biol 1987;104(5):1193
preprokallikrein
EC 3.4.21.-
*Enzyme Precursors
*Prekallikrein.
Adv Exp Med Biol 1986;198(Pt A):181
preceruloplasmin
EC 1.16.3.-
*Ceruloplasmin
*Enzyme Precursors.
Proc Natl Acad Sci USA 1986;83(14):5086
preprosubtilisin
EC 3.4.21.-
*Enzyme Precursors
*Subtilisins.
J Biol Chem 1986;261(22):10176
preprourokinase
EC 3.4.21.-
*Enzyme Precursors
*Urokinase-Type Plasminogen Activator.
Gene 1985;36(1-2):183
prostromelysin
EC 3.4.24.-
*Enzyme Precursors
*Metalloendopeptidases.
J Biol Chem 1986;261(6):2810
prelysozyme c
EC 3.2.1.-
*Enzyme Precursors
*Muramidase.
J Biol Chem 1986;261(5):2309
procalpain
EC 3.4.22.-
*Calpain
*Enzyme Precursors.
Biochim Biophys Acta 1985;831(3):335
protosubtilin
97397-14-3 Protosubtilin
*Enzyme Precursors
*Peptide Hydrolases.
Prikl Biokhim Mikrobiol 1984;20(1):88
pro-
phenoloxidase
EC 1.10.3.-
*Catechol Oxidase
*Enzyme Precursors.
Biochem Biophys Res Commun 1983;113(2):562
pre-
beta-
lactamase
EC 3.5.2.-
*beta-Lactamases
*Enzyme Precursors.
J Cell Biol 1983;96(4):1117
procolipase
72994-53-7 Lipase cofactor, pro
*Colipases
*Enzyme Precursors.
Biochim Biophys Acta 1983;742(1):39
pro-
proteinase E
EC 3.4.-
*Enzyme Precursors
*Endopeptidases.
Biochem J 1982;205(2):449
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