encyclopedia of medical concepts
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Protein C
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Definition
: A vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomodulin exerts anticoagulant properties by inactivating factors Va and VIIIa at the rate-limiting steps of thrombin formation.
Pharmacological Action
Anticoagulants
;
Fibrinolytic Agents
Substance
CAS Registry & name
Categories
Source
Drugs
*
protein C Padua2, human
0
*Protein C.
Thromb Res 2006;117(5):523-8
PROCR protein, human
0
*Receptors, Cell Surface
*Antigens, CD
Endothelium, Vascular
Protein C.
J Thromb Haemost. 2003 Apr;1(4):855-6
protein C Padua3
0
*Protein C.
Thromb Haemost 2001 Oct;86(4):1017-22
drotrecogin alfa activated
0
*Protein C
Recombinant Proteins
Fibrinolytic Agents.
Pharma Action
Anti-Infective Agents
N Engl J Med 2001 Mar 8;344(10):699-706; N Engl J Med 2006 Oct 19;365(16):1640-1642
XIGRIS
protein C Nagoya, human
0
*Protein C.
Blood 1998 May 15;91(10):3784-91
protein C Osaka 3
0
*Protein C.
Thromb Haemost 1994 Jan;71(1):32-7
protein C Osaka 2
0
*Protein C.
Thromb Haemost 1994 Jan;71(1):32-7
protein C Osaka 1
0
*Protein C.
Thromb Haemost 1994 Jan;71(1):32-7
protein C Yonago
0
*Protein C.
Thromb Res 1991;63(2):249
protein C, Rouen
0
*Protein C.
Thromb Res 1989;56(3):387
protein C London 1
0
Protein C/*analogs & derivatives.
Nucleic Acids Res 1989;17(24):10513
protein C propeptide
0
*Protein C
*Protein Precursors.
Biochemistry 1987;26(22):7003
protein C, des-
1-
41 light chain activated
42617-41-4
*Peptide Fragments
*Protein C.
J Biol Chem 1986;261(32):14991
snake venom protein C activator
0
*Peptides
Protein C.
Pharma Action
Fibrinolytic Agents
Thromb Res 1986;43(3):253
protein C activator peptide
0
*Oligopeptides
Enzyme Activation
Peptide Hydrolases
Protein C.
Ann Biol Clin (Paris) 1985;43(4):451
