ψ 
ψ 
Dihydroergotoxine 
A mixture of three different hydrogenated derivatives of ERGOTAMINE: DIHYDROERGOCORNINE; DIHYDROERGOCRISTINE; and DIHYDROERGOCRYPTINE. Dihydroergotoxine has been proposed to be a neuroprotective agent and a nootropic agent. The mechanism of its therapeutic actions is not clear, but it can act as an alpha-adrenergic antagonist and a dopamine agonist. The methanesulfonate salts of this mixture of alkaloids are called ERGOLOID MESYLATES.     
Pharmacological Action Nootropic Agents; Adrenergic alpha-Antagonists; Neuroprotective Agents; Dopamine Agonists
See Also Dihydroergocornine; Dihydroergocryptine; Dihydroergocristine
Other names Ergot Alkaloids, Hydrogenated; Co-Dergocrine; Hydrogenated Ergot Alkaloids; Alkaloids, Hydrogenated Ergot; Dihydroergotoxin; Ergot Alkaloids, Hydrogenated; Co-Dergocrine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Briserin  55128-93-3   *Clopamide *Dihydroergotoxine *Reserpine Drug Combinations.  Praxis 63(47):1409;1974
sandoven  61498-93-9   *Dihydroergotoxine *Esculin *Rutin Drug Combinations.  Praxis 64(41):1320;1975
Vasobral  94423-99-1   *Caffeine *Dihydroergotoxine Drug Combinations.  Arm Radiol 1987;30(6):425
sinepres  117178-63-9   *Dihydroergotoxine *Hydrochlorothiazide *Reserpine Drug Combinations.  Klin Med (Mosk) 1987;65(4):30
crystepin T  90155-20-7 Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2'-(1-methylethyl)-5'-(phenylmethyl)-, (5'alpha,10alpha)-, mixt. with 2-chloro-5-(2,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl)benzenesulfonamide and 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-2,3,6  *Chlorthalidone *Dihydroergotoxine *Metipranolol Drug Combinations.  Cas Lek Cesk 1983;122(29):906
Eutergine  0   *Dihydroergotoxine *Papaverine *Sparteine Drug Combinations Cerebrovascular Disorders/drug therapy.  Lille Med 17(5):819;1972
Iskedyl  96743-85-0 Oxayohimban-16-carboxylic acid, 16,17-didehydro-19-methyl-, methyl ester, (19alpha)-, mixt. with (5'alpha,10alpha)-9,10-dihydro-12'-hydroxy-2'-(1-methylethyl)-5'-(phenylmethyl)ergotaman-3',6',18-trione  *Dihydroergotoxine *Yohimbine Drug Combinations.  Ann Anesthesiol Fr 16(2):69;1975; J Fr Otorhinolaryngol 23(7):649;1974
defluina  52623-83-3   *Dihydroergotamine *Dihydroergotoxine *Yohimbine Drug Combinations.  Fortschr Med 4(27):1502;1976; Fortschr Med 96(34):1735;1978
Crystepin CH  80434-87-3 Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-((3,4,5-trimethoxybenzoyl)oxy)-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)-, mixt. with 2-chloro-5-(2,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl)benzenesulfonamide and (5'alpha,10alpha)-9,10-dihyd  *Chlorthalidone *Dihydroergotoxine *Reserpine Drug Combinations.  Cas Lek Cesk 1981;120(34):1030
P 3007  115756-35-9   *Dihydroergotoxine Drug Combinations 5-Hydroxytryptophan/*analogs & derivatives.  Clin Ther 1987;9(3):267
Ersilan  135556-19-3   *Dihydroergotoxine Drug Combinations Theophylline/*analogs & derivatives.  Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralov 1988;31(5 Suppl):649
bivelin  76986-91-9 Ergotoxine, dihydro-, mono(ethyl sulfate) (salt), mixt. with 2-(diethylamino)-4-methylpentyl 4-aminobenzoate  *Dihydroergotoxine Drug Combinations Procaine/*analogs & derivatives.  Klin Oczna 44(7):661;1974; Pol Tyg Lek 33(41):1619;1978; Rev Med-Chirurg 69(3):407;1975
dihydroergotoxine ethansulfonate  1401-12-3   Dihydroergotoxine.  Nouv Presse Med 7(24):2175;1978; Ther Hung 25(4):145;1977