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Yohimbine

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Definition: A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic in the treatment of ERECTILE DYSFUNCTION.     
Pharmacological Action Adrenergic alpha-2 Receptor Antagonists; Mydriatics
Examples Reserpine
Other names Rauwolscine; Tartrate, Corynanthine; Hydrochloride, Yohimbine; Hydrochloride, Aphrodine; Yohimex; Yohimbine Hydrochloride; Yohimbine Houd+¬; Yohimbin Spiegel; Yocon; StegroPharm Brand of Yohimbine Hydrochloride; Star Brand of Yohimbine Hydrochloride; Solvay Brand of Yohimbine Hydrochloride; Rauhimbine; Pluriviron; Palisades Brand of Yohimbine Hydrochloride; Kramer Brand of Yohimbine Hydrochloride; Glenwood Brand of Yohimbine Hydrochloride; Corynanthine Tartrate; Corynanthine; Aventis Brand of Yohimbine Hydrochloride
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
yohimbine-arginine combination  0   *Arginine *Yohimbine Drug Combinations. Br J Clin Pharmacol 2005 Jan;59(1):85-93
9-methoxy-3-epi-alpha-yohimbine  0   Yohimbine/*analogs & derivatives. Chem Pharm Bull (Tokyo) 2004 Mar;52(3);359-61
lipokinetix  0   *Benzofurans *Caffeine *Diiodothyronines *Phenylpropanolamine *Yohimbine. Ann Intern Med 2002 Apr 16;136(8):590-5
rauwolscine-OHPC  0   Yohimbine/*analogs & derivatives. Neurochem Int 2000 Jan;36(1):7-18
iodinated rauwolscine-OHPC  0   Yohimbine/*analogs & derivatives Iodine Radioisotopes. Neurochem Int 2000 Jan;36(1):7-18
NMI 187  0   Yohimbine. J Pharmacol Exp Ther 1999 Jul;290(1):121-8
trimethoxybenzoylyohimbine  0   Yohimbine/*analogs & derivatives. Biochem Pharmacol 1998 Sep 15;56(6):719-27
11-hydroxy-yohimbine  0   Yohimbine/*analogs & derivatives. Eur J Clin Pharmacol 1997;52(2):135-8
11-hydroxyyohimbine  140405-13-6 Yohimban-16-carboxylic acid, 11,17-dihydroxy-, methyl ester, (16alpha,17alpha)  Yohimbine/*analogs & derivatives. Br J Pharmacol 1993 Apr;108(4):927-32
10-hydroxyyohimbine  41928-02-3 Yohimban-16-carboxylic acid, 10,17-dihydroxy-, methyl ester, (16alpha,17alpha)  Yohimbine/*analogs & derivatives. Br J Pharmacol 1993 Apr;108(4):927-32
yohimbine-agarose matrix  0   Sepharose/*analogs & derivatives Yohimbine/*analogs & derivatives. Methods Enzymol 1992;215:181-200
5-carboxytetrahydroalstonine  133541-29-4   Yohimbine/*analogs & derivatives. Acta Crystallogr C 1991;47(Pt 2):464
atropine, dipyridamole, ifenprodil tartrate, papaverine, piribedil, yohimbine drug combination  0   *Atropine *Dipyridamole *Papaverine *Piperidines *Piribedil *Yohimbine Drug Combinations. J Urol 1991;145(2):287
14-benzoyloxyyohimbine  90362-87-1   Yohimbine/*analogs & derivatives. J Pharm Pharmacol 1987;39(6):439
14-(4-nitrobenzoyloxy)yohimbine  109460-90-4   Yohimbine/*analogs & derivatives. J Pharm Pharmacol 1987;39(6):439
17-hydroxy-20-yohimban-16-(N-(4-azido-3-iodo)phenyl)carboxamide  108206-16-2   *Azides Yohimbine/*analogs & derivatives. Hypertension 1987;9(6 Pt 2):III-120
rauwolscine 4-aminophenylcarboxamide  108206-13-9   Yohimbine/*analogs & derivatives. Hypertension 1987;9(6 Pt 2):III-120
1-methylyohimbine  5057-80-7   Yohimbine/*analogs & derivatives. Res Commun Chem Pathol Pharmacol 1985;48(2):243
apoyohimbine  2671-50-3   Yohimbine/*analogs & derivatives. Br J Pharmacol 1984;82(4):769
almitrine, raubasine drug combination  76997-30-3   *Yohimbine *Almitrine Drug Combinations.
Pharma Action Neuroprotective Agents
Presse Med 1983;12(13):823
Isosarpan  57063-25-9 Oxayohimban-16-carboxylic acid, 16,17-didehydro-19-methyl-, methyl ester, (19alpha)-, mixt. with 4-(1-hydroxy-2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-1,2-benzenediol  *Piperazines *Yohimbine Drug Combinations. Acta Neurol 34(1):45;1979; Sem Hop Paris 50(10):611;1975; Therapeutique 47(9):815;1971
Pasuma (injection)  0   *Testosterone *Vitamin E Drug Combinations Strychnine/*analogs & derivatives Yohimbine/*analogs & derivatives. S Afr Med J 53(18):693;1978
yohimbinic acid  522-87-2 Yohimban-16-carboxylic acid, 17-hydroxy-, (16alpha,17alpha)  Yohimbine/*analogs & derivatives. Biopolymers 15(5):977;1976
Iskedyl  96743-85-0 Oxayohimban-16-carboxylic acid, 16,17-didehydro-19-methyl-, methyl ester, (19alpha)-, mixt. with (5'alpha,10alpha)-9,10-dihydro-12'-hydroxy-2'-(1-methylethyl)-5'-(phenylmethyl)ergotaman-3',6',18-trione  *Dihydroergotoxine *Yohimbine Drug Combinations. Ann Anesthesiol Fr 16(2):69;1975; J Fr Otorhinolaryngol 23(7):649;1974
afrodex  8054-03-3 Afrodex  *Methyltestosterone *Strychnine *Yohimbine Drug Combinations. Curr Therap Res 16(1):96;1974
Pasuma (tablet)  0   *Caffeine *Ephedrine *Methyltestosterone *Vitamin E *Yohimbine Drug Combinations Strychnine/*analogs & derivatives. S Afr Med J 53(18):693;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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