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Reserpine

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Definition: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.  reserpine derivatives=RESERPINE /analogs   
Pharmacological Action Antipsychotic Agents; Adrenergic Uptake Inhibitors; Antihypertensive Agents 		Other names V Serp; Vitarine Brand of Reserpine; Vangarde Brand of Reserpine; V-Serp; Serpivite; Serpasil; Rausedyl; Rausedil; Raupasil; RaunervilDrugs* : RAU-SED; SERPIVITE; SANDRIL; SERPANRAY; HISERPIA; SERPALAN; SERPASIL; RESERPINE; SERPATE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
reserpine methonitrate  0   Reserpine/*analogs & derivatives. BMC Pharmacol 2004 Nov 16;4(1):30
rescinamine  0   Reserpine/*analogs & derivatives. Anal Sci 2001 Jul;17(7):865-8
deserpidine  131-01-1   Reserpine/*analogs & derivatives. ORETICYL FORTE; METHYCLOTHIAZIDE AND DESERPIDINE; ENDURONYL FORTE; ENDURONYL; ORETICYL 50; HARMONYL; ORETICYL 25
rescinnamine  24815-24-5 Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-((1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)oxy)-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)  Reserpine/*analogs & derivatives. MODERIL; CINNASIL
syrosingopine  84-36-6 Yohimban-16-carboxylic acid, 18-((4-((ethoxycabonyl)oxy)-3,5-dimethoxybenzoyl)oxy)-11,17-dimethoxy-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)  Reserpine/*analogs & derivatives.
sinepres  117178-63-9   *Dihydroergotoxine *Hydrochlorothiazide *Reserpine Drug Combinations. Klin Med (Mosk) 1987;65(4):30
methyl reserpate  2901-66-8   Reserpine/*analogs & derivatives. J Neurochem 1987;48(3):949
16,18-reserpinediol  482-98-4   Reserpine/*analogs & derivatives. J Neurochem 1987;48(3):949
reserpic acid  83-60-3   Reserpine/*analogs & derivatives. J Biol Chem 1985;260(20):10981
Regroton  8058-25-1   *Chlorthalidone *Reserpine Drug Combinations. J Natl Med Assoc 1984;76(11):1048REGROTON; DEMI-REGROTON
bromoreserpine  84057-91-0 Yohimban-16-carboxylic acid, bromo-11,17-dimethoxy-18-((3,4,5-trimethoxybenzoyl)oxy)-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)  Reserpine/*analogs & derivatives. JPMA 1982;32(6):141
dibromoreserpine  84057-90-9 Yohimban-16-carboxylic acid, dibromo-11,17-dimethoxy-18-((3,4,5-trimethoxybenzoyl)oxy)-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)  Reserpine/*analogs & derivatives. JPMA 1982;32(6):141
clopamide, dihydroergochristine, reserpine drug combination  0   *Clopamide *Reserpine *Dihydroergocristine Drug Combinations. Cas Lek Cesk 1981;120(34):1030
dihydralazine, reserpine drug combination  0   *Dihydralazine *Reserpine Drug Combinations. Mutat Res 67(3):295;1979
enderpins  0   *Reserpine. Biul Eksp Biol Med 86(8):170;1978
CD 3400  35440-49-4 yohimban-16-carboxylic acid, 18-((3-(4-hydroxy-3-methoxyphenyl)-1-oxo-2-propenyl)oxy)-11,17-dimethoxy-, methyl ester, (3 beta,16 beta,17 alpha,18 beta,20 alpha)  Reserpine/*analogs & derivatives. Folia Pharmacol Jpn 72(8):969;1976; Folia Pharmacol Jpn 73(7):734;1977; Jpn J Pharmacol 27:87;1977
meprocalm  8060-44-4 Meprocalm  *Meprobamate *Reserpine Drug Combinations. Acta Neurol Belg 73(2):88;1973
mefrusid, methyldopa, reserpine drug combination  0   *Mefruside *Methyldopa *Reserpine Drug Combinations. Med Monatschr 27(9):418;1973
aldatense  76270-05-8 Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-((1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)oxy)-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)-, mixt. with 6-chloro-3,4-dihydro-3-((2-propenylthio)methyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide   *Canrenoate Potassium *Sulfonamides Drug Combinations Reserpine/*analogs & derivatives. Minerva Cardioangiolog 2(9):585;1973
dihydralazine - hydrochlorothiazide - reserpine drug combination  0   *Hydralazine *Hydrochlorothiazide *Reserpine Drug Combinations. Vrach Delo 1979;9:62; Wien Klin Woch 85(27):499;1973
Hyparez  77630-46-7 Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-((3,4,5-trimethoxybenzoyl)oxy)-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)-, mixt. with 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 1(2H)-phthalazinone hydrazone and   *Hydralazine *Hydrochlorothiazide *Potassium Chloride *Reserpine Drug Combinations. Vrach Delo 1:16;1973
bietaserpine  53-18-9 methyl 13-(2-diethylaminoethyl)-2,11-dimethoxy-3-(3,4,5-trimethoxybenzoyloxy)yohimban-1-carboxylic acid  Reserpine/*analogs & derivatives.
clopamide, dihydroergotoxine, reserpine drug combination  0   *Clopamide *Dihydroergotoxine *Reserpine Drug Combinations. Praxis 63(47):1409;1974
FH 109 C  0   *Benzothiadiazines *Canrenoate Potassium Reserpine/*analogs & derivatives.
Nortensin  58934-32-0 Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-((3,4,5-trimethoxybenzoyl)oxy)-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)-, mixt. with 5-(aminosulfonyl)-4-chloro-2-((2-furanylmethyl)amino)benzoic acid  *Furosemide *Reserpine Drug Combinations.
butabarbital, hydrochlorothiazide, reserpine drug combination  0   *Barbiturates *Hydrochlorothiazide *Reserpine Drug Combinations.
inositol nicotinate, mefruside, reserpine drug combination  0   *Mefruside *Nicotinic Acids *Reserpine Drug Combinations.
Pharma Action Antihypertensive Agents 		Med Klin 70(3):102;1975; Med Welt 37:1617;1970

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