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Ergoloid Mesylates

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Definition: A mixture of the mesylates (methane sulfonates) of DIHYDROERGOCORNINE; DIHYDROERGOCRISTINE; and the alpha- and beta-isomers of DIHYDROERGOCRYPTINE. The substance produces a generalized peripheral vasodilation and a fall in arterial pressure and has been used to treat symptoms of mild to moderate impairment of mental function in the elderly.     
Pharmacological Action Adrenergic alpha-Antagonists; Nootropic Agents; Vasodilator Agents 		Other names Dihydroergotoxine Mesylate; Co-Dergocrine Mesylate; Monomethanesulfonate, Dihydroergotoxine; Methanesulfonate, Dihydroergotoxine; Co Dergocrine Mesylate; Co Dergocrine Mesilate; Co Dergine Mesylate; Redergine; Redergin; Redergam; Hydergine; Ergotoxin, Dihydro-, Monomethasulfonate; Ergoloid Mesylate; Ergodesit; Dihydroergotoxine Monomethanesulfonate; Dihydroergotoxine Methanesulfonate; Co-Dergocrine Mesilate; Co-Dergine Mesylate; CircanolDrugs* : ERGOLOID MESYLATES; CIRCANOL; DEAPRIL-ST; HYDROGENATED ERGOT ALKALOIDS; ALKERGOT; HYDERGINE LC; HYDERGINE; GERIMAL
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
nifedipine-co-dergocrine combination  0   *Ergoloid Mesylates *Nifedipine Drug Combinations. Eur J Drug Metab Pharmacokinet 1992 Jan-Mar;17(1):33-8
dihydroergovaline  3036-37-1 (5' alpha)-9,10-dihydro-12'-hydroxy-2'- methyl-5'-(1-methylethyl)ergotaman-3',6',18-trione  *Ergoloid Mesylates. Med Welt 30(31-32):1166;1979
dihydroergonine  35167-84-1 2'-ethyl-9,10-dihydro-12'-hydroxy-5'-(1-methylethyl)ergotaman-3',6',18-trione  *Ergoloid Mesylates. Klin Wochenschr 56(Suppl 1):139;1978
dihydroergostin  3609-19-6 Ergotaman-3',6',18-trione, 2'-ethyl-9,10-dihydro-12'-hydroxy-5'-(phenylmethyl)-, (5'alpha,10alpha)  *Ergoloid Mesylates. Vasa 3(1):72;1974
acetergamine  3031-48-9 (+)-N-acetyl-9,10-dihydrolysergamine  *Ergoloid Mesylates. Minerva Ginecol 24(3):133;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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