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Vindesine
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Definition
: Vinblastine derivative with antineoplastic activity against CANCER. Major side effects are myelosuppression and neurotoxicity. Vindesine is used extensively in chemotherapy protocols (ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS).
Pharmacological Action
Antineoplastic Agents, Phytogenic
;
Tubulin Modulators
Other names
Sulfate, Vindesine; NSC245467; NSC 245467; Vindesine Sulfate; Vindesin; NSC-
245467; Lilly Brand of Vindesine Sulfate; Enison; Eldisine; EG Labo Brand of Vindesine Sulfate; Desacetylvinblastine Amide; Compound 112531
Substance
CAS Registry & name
Categories
Source
Drugs
*
MOPPEBVCAD protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Bleomycin
Doxorubicin/*analogs & derivatives
Lomustine
Mechlorethamine
Melphalan
Prednisone
Procarbazine
Vinblastine
Vincristine
Vindesine.
J Clin Oncol. 2005 Dec 20;23(36):9198-207
BEMP protocol 2
0
*Antineoplastic Combined Chemotherapy Protocols
Bleomycin
Cisplatin
Vindesine
Mitomycin.
Ann Oncol 2001 Jul;12(7):967-74
OPP-
EBV-
CAD regimen
0
*Antineoplastic Combined Chemotherapy Protocols
Prednisone
Vincristine
Vindesine
Epirubicin.
Leuk Lymphoma 2000 Dec;40(1-2):87-94
Cis-
VACD protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Cyclophosphamide
Dexamethasone
Doxorubicin
Vindesine.
Leuk Lymphoma 1999 Nov;35(5-6):613-8
HELP protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Doxorubicin
Ifosfamide
Methotrexate
Vindesine.
Ann Oncol 1999 Sep;10(9):1065-71
LSG15 regimen
0
*Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Doxorubicin
Etoposide
Nitrosourea Compounds
Prednisolone
Vincristine
Vindesine
Carboplatin.
Int J Hematol 1999 Feb;69(2):92-5
VQEP protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Carbazilquinone
Cyclophosphamide
Prednisolone
Vindesine.
Br J Cancer 1997;76(11):1484-8
VEMP protocol 3
0
*Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Methotrexate
Prednisolone
Vindesine.
Br J Cancer 1997;76(11):1484-8
HR-
2 protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Asparaginase
Daunorubicin
Dexamethasone
Ifosfamide
Methotrexate
Prednisolone
Thioguanine
Vindesine.
Blood 1996 Apr 15;87(8):3143-50
EPVP protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Etoposide
Prednisolone
Procarbazine
Vindesine.
Gan To Kagaku Ryoho 1996 Mar;23(4):499-501
LNH 87 protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Bleomycin
Cyclophosphamide
Doxorubicin
Prednisone
Vindesine.
Blood 1996 Jan 1;87(1):265-72
PECC protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Carmustine
Cyclophosphamide
Prednisone
Vindesine.
J Clin Oncol 1994 Dec;12(12):2706-13
OS 87 protocol
0
Cisplatin
Doxorubicin
*Antineoplastic Combined Chemotherapy Protocols
Leucovorin
Ifosfamide
Methotrexate
Vindesine.
J Clin Oncol 1994 Dec;12(12):2614-20
CEVD protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Dexamethasone
Etoposide
Lomustine
Vindesine.
Leuk Lymphoma 1994 Jun;14(1-2):79-89
PEEC-
M protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Chlorambucil
Etoposide
Methotrexate
Methylprednisolone
Vindesine.
Br J Cancer 1994 Sep;70(3):501-5
MCNU-
VMP protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Melphalan
Nitrosourea Compounds
Prednisolone
Vindesine.
Int J Hematol 1994 Feb;59(2):113-23
DVP protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Dacarbazine
Vindesine.
Am J Clin Oncol 1994 Feb;17(1):55-9
MICE regimen
0
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Ifosfamide
Vindesine
Mitomycin.
Eur J Cancer 1993;29A:1848-50
LNH87-
2 protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Bleomycin
Cyclophosphamide
Methotrexate
Methylprednisolone
Vindesine.
Ann Oncol 1993 Sep;4(8):651-6
VIP protocol 3
0
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Ifosfamide
Vindesine.
Am J Clin Oncol 1993 Aug;16(4):310-4
CAD protocol 2
0
*Antineoplastic Combined Chemotherapy Protocols
Doxorubicin
Lomustine
Vindesine.
J Clin Oncol 1993 Apr;11(4):712-9
LNH-
80 regimen
0
*Antineoplastic Combined Chemotherapy Protocols
Bleomycin
Cyclophosphamide
Doxorubicin
Vindesine.
Ann Oncol 1992 Sep;3(8):639-44
MV protocol 2
0
*Antineoplastic Combined Chemotherapy Protocols
Vindesine
Mitomycin.
Cancer Chemother Pharmacol 1992;30(3):212-4
IVEP protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Etoposide
Ifosfamide
Prednisolone
Vindesine.
Hematol Oncol 1991;9(4-5):217
MTV protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Thiotepa
Vindesine
Mitomycin.
Ann Oncol 1991;2(5):347
VAE protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Etoposide
Vindesine.
Br J Haematol 1991;77(4):486
EV protocol
0
Vindesine
*Antineoplastic Combined Chemotherapy Protocols
Etoposide.
Ann Oncol 1990;1(2):128
PCV regimen
0
Cisplatin
*Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Vindesine.
Cancer 1990;65(11):2435
MB-
triple V protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine/analogs & derivatives
Etoposide
Mitoxantrone
Vincristine
Vindesine.
Gan To Kagaku Ryoho 1989;16(12):3729
VINAP protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Lomustine
Prednisolone
Vindesine.
Sangre (Barc) 1989;34(2):107
LNH 84 protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Bleomycin
Cyclophosphamide
Doxorubicin
Prednisolone
Vindesine.
J Clin Oncol 1989;7(8):1018
PEEC protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Chlorambucil
Etoposide
Methylprednisolone
Vindesine.
Scott Med J 1988;33(6):360
EVI protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Etoposide
Ifosfamide
Vindesine.
Eur J Cancer Clin Oncol 1987;23(8):1197
VMMc protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Mitomycins
Mitoxantrone
Vindesine.
Cancer Treat Rep 1987;71(9):845
VPIV protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Ifosfamide
Podophyllotoxin
Vindesine.
Cancer Chemother Pharmacol 1986;18 Suppl 2:S40
MiPE protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Vindesine
Mitomycin.
Cancer Treat Rep 1986;70(9):1091
N-
(4-
azido-
3-
iodosalicyl)-
N'-
beta-
aminoethylvindesine
102976-56-7
*Azides
Vindesine/*analogs & derivatives.
J Biol Chem 1986;261(14):6137
N-
(4-
azidobenzoyl)-
N'-
beta-
aminoethylvindesine
103974-27-2
*Azides
Vindesine/*analogs & derivatives.
J Biol Chem 1986;261(14):6137
VinMCP protocol
0
Melphalan
*Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Prednisone
Vindesine.
Cancer 1986;57(2):226
ELETOP protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Etoposide
Vindesine.
Cancer 1986;57(1):44
VDA-
P protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Vindesine.
J Clin Oncol 1986;4(1):14
APEL protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Doxorubicin
Vindesine.
Presse Med 1985;14(19):1069
VCPC protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Cyclophosphamide
Lomustine
Vindesine.
Bull Cancer (Paris) 1985;72(1):25
BELD protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Bleomycin
Dacarbazine
Lomustine
Vindesine.
Cancer 1985;55(9):1879
VEP protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Etoposide
Prednisolone
Vindesine.
Semin Oncol 1985;12(1 Suppl 2):26
VCH protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Altretamine
Vindesine.
Cancer Treat Rep 1984;68(9):1179
EBAP protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Carmustine
Doxorubicin
Prednisone
Vindesine.
Cancer Treat Rep 1984;68(7-8):963
CAPE protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Doxorubicin
Prednisone
Vindesine.
Neth J Med 1984;27(2):25
CAD protocol 1
0
*Antineoplastic Combined Chemotherapy Protocols
Lomustine
Melphalan
Vindesine.
Am J Med 1984;76(2):270
DAC protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Doxorubicin
Vindesine.
Cancer 1983;52(7):1142
DECAV protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Dacarbazine
Cyclophosphamide
Doxorubicin
Vindesine.
Sem Hop Paris 1983;59(19):1441
CVB protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Bleomycin
Cisplatin
Vindesine.
Cancer 1983;51(6):1050