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Mitoxantrone
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Definition
: An anthracenedione-derived antineoplastic agent.
Pharmacological Action
Analgesics
;
Antineoplastic Agents
Other names
Mitozantrone; NSC301739D; NSC301739; NSC299195; NSC287836; NSC279836; NSC 301739D; NSC 301739; NSC 299195; NSC 287836; NSC 279836; Hydrochloride, Mitoxantrone; CL232325; CL 232325; Acetate, Mitoxantrone; Wyeth Brand of Mitoxantrone Hydrochloride; Ralenova; Pralifan; Onkotrone; Novantrone
Drugs
*
:
MITOXANTRONE HYDROCHLORIDE
;
NOVANTRONE
Substance
CAS Registry & name
Categories
Source
Drugs
*
BBR3378
0
Mitoxantrone/*analogs & derivatives
Antineoplastic Agents.
Clin Immunol. 2011 Dec;141(3):304-16
mitoxantrone 4'-
beta-
D-
glucoside
0
*Glucosides
Mitoxantrone/*analogs & derivatives.
Org Lett. 2011 May 20;13(10):2786-8
WRC 213
0
Methionine/*analogs & derivatives
Mitoxantrone/*analogs & derivatives
DNA Topoisomerases, Type II/antagonists & inhibitors.
Biochem Pharmacol 2008 Feb 15;75(4):847-56
EORTC GIMEMA AML-
13 protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Etoposide
Mitoxantrone
Idarubicin.
Haematologica 2007 May;92(5):605-11
EORTC GIMEMA AML-
10 protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Daunorubicin
Etoposide
Mitoxantrone
Idarubicin.
Haematologica 2007 May;92(5):605-11
R-
FCM protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Mitoxantrone
Vidarabine/analogs & derivatives
Antibodies, Monoclonal, Murine-Derived.
Leukemia 2007 Mar;21(3):524-8
LPA97R protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Etoposide
Mitoxantrone
Tretinoin.
Leukemia 2007 Mar;21(3):446-52
MRC AML 10 protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Amsacrine
Cytarabine
Daunorubicin
Etoposide
Mitoxantrone.
Pediatr Blood Cancer 2007 Mar;48(3):262-7
MEA protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Etoposide
Mitoxantrone.
Bone Marrow Transplant 2002 Dec;30(12):971-3
VEPEMB protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Mitoxantrone
Procarbazine
Vinblastine.
Tumori 2002 Jan-Feb;88(1 Suppl 1):S29-31
RIME regimen
0
*Antineoplastic Combined Chemotherapy Protocols
Etoposide
Ifosfamide
Mitoxantrone
Antibodies, Monoclonal, Murine-Derived.
Eur J Haematol Suppl 2001 Jul;(64):56-62
MAC chemotherapy protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Mitoxantrone.
Blood 2001 Sep 1;98(5):1302-11
MECA protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Etoposide
Mitoxantrone
Carboplatin.
Leuk Lymphoma 2000 Nov;39(5-6):613-24
MIFAP regimen
0
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Cytarabine
Mitoxantrone
Vidarabine/analogs & derivatives.
J Cancer Res Clin Oncol 2001;127(6):387-95
CMC protocol 2
0
*Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Mitoxantrone
Cladribine.
Eur J Haematol 2001 Mar;66(3):188-94
TAM protocol
0
Mitoxantrone
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Topotecan.
Ann N Y Acad Sci 2000;922:326-9
MiCMA protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Methylprednisolone
Mitoxantrone
Carboplatin.
Ann Oncol. 2000 Jul;11(7):867-71
CN3OP regimen
0
*Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Prednisone
Mitoxantrone
Vincristine.
Med Oncol 2000 Aug;17(3):195-202
MINT protocol
0
Mesna
*Antineoplastic Combined Chemotherapy Protocols
Ifosfamide
Mitoxantrone
Taxoids.
Invest New Drugs 1999;17(2):187-92
FLAM regimen
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Mitoxantrone
Vidarabine/analogs & derivatives.
Cancer 1999 Dec 1;86(11):2246-51
MCP protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Chlorambucil
Mitoxantrone
Prednisolone.
Clin Oncol (R Coll Radiol)1999;11(3):184-6
GEMIA protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Etoposide
Mitoxantrone.
Haematologica 1999 Mar;84(3):226-30
CMD protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Dexamethasone
Mitoxantrone
Cladribine.
Leuk Lymphoma 1999 Jan;32(3-4):359-63
OPEN protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Etoposide
Mitoxantrone
Prednisone
Vincristine.
Blood 1999 Apr 1;93(7):2202-7
MVC protocol 2
0
*Antineoplastic Combined Chemotherapy Protocols
Lomustine
Mitoxantrone
Vinblastine.
Cancer J Sci Am 1998 Jul-Aug;4(4):254-60
MCNO regimen
0
*Antineoplastic Combined Chemotherapy Protocols
Methotrexate
Mitoxantrone
Vincristine
Carboplatin.
Oncology 1998 Mar-Apr;55(2):139-44
PMitCEBO protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Bleomycin
Cyclophosphamide
Etoposide
Mitoxantrone
Prednisolone
Vincristine.
Acta Oncol 1997;36(6):573-6
MLL-
93 protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Asparaginase
Leucovorin
Cyclophosphamide
Cytarabine
Dexamethasone
Etoposide
Hydrocortisone
Hydroxyurea
Methotrexate
Mitoxantrone.
Leuk Res 1997 Sep;21(9):811-5
(mitoxantrone)cerium(IV)
0
*Organometallic Compounds
Mitoxantrone/*analogs & derivatives
Cerium.
J Inorg Biochem 1997 Nov 1;68(2):117-21
MIMO protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Methotrexate
Mitoxantrone
Vincristine.
Oncology 1997 Sep-Oct;54(5):371-5
NCVB protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Bleomycin
Cyclophosphamide
Mitoxantrone
Vincristine.
J Clin Oncol 1997 Mar;15(3):1131-7
MAD protocol
0
Cytarabine
*Antineoplastic Combined Chemotherapy Protocols
Dexamethasone
Mitoxantrone
Granulocyte Colony-Stimulating Factor.
J Clin Oncol 1997 Feb;15(2):491-8
BF-
9 protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Daunorubicin
Etoposide
Mitoxantrone
Thioguanine.
Eur J Obstet Gynecol Reprod Biol 1995 Dec;63(2):139-41
FMN regimen
0
*Antineoplastic Combined Chemotherapy Protocols
Fluorouracil
Mitoxantrone
Vinblastine/analogs & derivatives.
J Infus Chemother 1996 Spring;6(2):102-6
FLANG protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Mitoxantrone
Vidarabine/analogs & derivatives
Granulocyte Colony-Stimulating Factor.
Leuk Lymphoma 1996 Jun;22(1-2):173-6
TEMP protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Etoposide
Mitoxantrone
Tamoxifen.
Cancer 1996 Nov 1;78(9):1906-11
PmM protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Mitoxantrone
Prednimustine.
Leukemia 1996 May;10(5):836-43
mitoxantrone-
copper(II)
0
*Organometallic Compounds
Mitoxantrone/*analogs & derivatives
Copper.
J Inorg Biochem 1996 May 1;62(2):137-45
TNT protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Mitoxantrone
Thiotepa
Taxoids.
Ann N Y Acad Sci 1995 Dec 29;770:288-304
MITT protocol
0
Mitoxantrone
*Antineoplastic Combined Chemotherapy Protocols
Thiotepa.
Ann N Y Acad Sci 1995 Dec 29;770:288-304
P-
COMM-
B protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Bleomycin
Cyclophosphamide
Methotrexate
Mitoxantrone
Prednisolone
Vincristine.
Leuk Lymphoma 1995 Jun;18(1-2):137-43
MINE-
BOP protocol
0
Mesna
*Antineoplastic Combined Chemotherapy Protocols
Bleomycin
Etoposide
Ifosfamide
Mitoxantrone
Prednisone
Vincristine.
Acta Oncol 1995;34(7):937-40
HD-
CNV protocol
0
Etoposide
*Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Mitoxantrone.
J Clin Oncol 1995 Oct;13(10):2483-9
CNV protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Mitoxantrone
Vincristine.
J Clin Oncol 1995 Oct;13(10):2483-9
FMP regimen
0
*Antineoplastic Combined Chemotherapy Protocols
Mitoxantrone
Prednisone
Vidarabine/analogs & derivatives.
Eur J Haematol 1995 Oct;55(4):262-6
MMIP protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Ifosfamide
Methotrexate
Mitoxantrone
Prednisolone.
Rinsho Katsueki 1995 Feb;36(2):106-14
VIMB protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Bleomycin
Etoposide
Ifosfamide
Mitoxantrone.
J Clin Oncol 1995 Apr;13(4):953-60
MINE protocol
0
Mesna
*Antineoplastic Combined Chemotherapy Protocols
Etoposide
Ifosfamide
Mitoxantrone.
Invest New Drugs 1994;12(3):217-22
cyclone protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Mitoxantrone.
Can Vet J 1994 Nov;35(11):706-8
MVPP-
Bleo protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Bleomycin
Mitoxantrone
Prednisone
Procarbazine
Vincristine.
Leuk Lymphoma 1994 Sep;15(1-2):153-7
T-
NOP protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Mitoxantrone
Prednisone
Thiotepa
Vincristine.
Semin Oncol 1995 Feb;22(1 Suppl 1):21-4
TMJ protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Mitoxantrone
Thiotepa
Carboplatin.
J Med 1994;25(3-4):241-50
3M protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Methotrexate
Mitomycins
Mitoxantrone.
Br J Cancer 1994 Nov;70(5):980-3
PEN protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Etoposide
Mitoxantrone
Prednisone.
Semin Hematol 1994 Apr;31(2 Suppl 3):23-9
MVF protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Fluorouracil
Mitoxantrone
Vincristine.
Breast Cancer Res Treat 1993 Dec;28(3):291-4
NOPP protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Mitoxantrone
Prednisone
Procarbazine
Vincristine.
Ann Oncol 1994;5 Suppl 2;73-7
VNCOP-
B protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Bleomycin
Cyclophosphamide
Etoposide
Mitoxantrone
Prednisone
Vincristine.
Haematologica 1993 Nov-Dec;78(6):378-82
FND protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Dexamethasone
Mitoxantrone
Vidarabine/analogs & derivatives.
J Clin Oncol 1994 Mar;12(3):575-9
MFL combination
0
*Antineoplastic Combined Chemotherapy Protocols
Leucovorin
Fluorouracil
Mitoxantrone.
Am J Clin Oncol 1994 Feb;17(1):45-9
MECP protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Etoposide
Mitoxantrone
Prednisolone
Carboplatin.
Gan To Kagaku Ryoho 1994 Feb;21(2):237-41
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