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Vaccines, Synthetic

More information in Books or onNLM PubMed
Definition: Small synthetic peptides that mimic surface antigens of pathogens and are immunogenic, or vaccines manufactured with the aid of recombinant DNA techniques. The latter vaccines may also be whole viruses whose nucleic acids have been modified.  IM general only; coord NIM with specific vaccine (IM)   
Examples Vaccines, DNA; Vaccines, Edible; Vaccines, Virosome; Vaccines, Virus-Like Particle 		Other names Vaccines, Recombinant; Synthetic Vaccines; Semisynthetic Vaccines; Molecular Vaccines; Immunogens, Synthetic; Chemical Vaccines; Antigens, Synthetic; Recombinant Vaccines; Vaccines, Semisynthetic; Vaccines, Molecular; Vaccines, Chemical; Synthetic Immunogens; Synthetic Antigens
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
VAX102 vaccine  0   *Influenza Vaccines Vaccines, Synthetic. PLoS One 2010;5(12):e14442
MVA 85A  0   *Viral Vaccines Vaccines, Attenuated Vaccines, Synthetic. Nat Med 2004 Nov;10(11):1240-4
GI 5005  0   *Vaccines, Synthetic. Curr Opin Mol Ther 2009 Aug;11(4):456-62
PfCP2.9 vaccine  0   *Malaria Vaccines Vaccines, Synthetic. Vaccine 2008 Dec 9;26(52):6864-73
CpG ODN-OVA  0   *Oligodeoxyribonucleotides *Ovalbumin Vaccines, Synthetic. Allergol Int 2006 Mar;55(1):43-8
Fendrix  0   *Hepatitis B Vaccines Vaccines, Synthetic. Klin Mikrobiol Infekc Lek. 2006 Jun;12(3):87-90
Omp31 protein, Brucella melitensis (48-74)  0   *Bacterial Outer Membrane Proteins *Peptide Fragments Vaccines, Synthetic. Infect Immun 2005 Dec;73(12):8079-88
MSP3 protein, Plasmodium falciparum (181-276)  0   *Antigens, Protozoan *Peptide Fragments Vaccines, Synthetic Malaria Vaccines. Infect Immun 2005 Dec;73(12):8017-26
pH3IH1 RNA vaccine  0   *Viral Vaccines Vaccines, Synthetic. Virology 2004 Dec 5;330(1):196-208
PfCSP DNA vaccine  0   *Malaria Vaccines *Vaccines, DNA Vaccines, Synthetic. Vaccine 2004 Apr 16;22(13-14):1592-603
Euvax-B  0   *Hepatitis B Vaccines Vaccines, Synthetic. Rev Panam Salud Publica 2004 Jan;15(1):35-40
rF-TRICOM vaccine  0   *Cancer Vaccines Vaccines, Synthetic. Hum Gene Ther 2003 May 20;14(8):803-27
rF-B7.1 vaccine  0   *Cancer Vaccines Vaccines, Synthetic. Hum Gene Ther 2003 May 20;14(8):803-27
GapC protein, Streptococcus  0   *Antigens, Bacterial *Bacterial Proteins Vaccines, Synthetic Streptococcal Vaccines. Vaccine 2002 May 22;20(17-18):2278-86
rV-Tricom  0   *Cancer Vaccines Vaccines, Synthetic. Hum Gene Ther 2001 Jul 20;12(11):1459-80
(T1BT)4-P3C polyoxime vaccine  0   *Oximes *Malaria Vaccines Vaccines, Synthetic. J Immunol 2001 Jan 1;166(1):481-9
streptococcal polysaccharide type II-tetanus toxoid conjugate vaccine  0   *Polysaccharides, Bacterial *Tetanus Toxoid Vaccines, Synthetic Vaccines, Conjugate. J Infect Dis 2000 Oct;182(4):1129-38
vaccinia-CEA vaccine  0   *Cancer Vaccines Vaccines, Synthetic. Clin Cancer Res 2000 Jan;6(2):34-41
ALVAC-CEA vaccine  0   *Cancer Vaccines Vaccines, Synthetic. Clin Cancer Res 2000 Jan;6(2):24-33
TA-Gw vaccine  0   *Viral Proteins Vaccines, Synthetic Viral Vaccines. J Infect Dis 1999 Mar;179(3):612-8
group B streptococcal type III capsular polysaccharide-tetanus toxoid vaccine  0   *Bacterial Capsules *Streptococcal Vaccines Vaccines, Synthetic Vaccines, Conjugate. J Infect Dis 1997 May;175(5):1237-9
group B streptococcal type Ib capsular polysaccharide-tetanus toxoid vaccine  0   *Bacterial Capsules *Streptococcal Vaccines Vaccines, Synthetic. J Infect Dis 1997 May;175(5):1237-9
group B streptococcal type Ia capsular polysaccharide-tetanus toxoid vaccine  0   *Bacterial Capsules *Streptococcal Vaccines Vaccines, Synthetic. J Infect Dis 1997 May;175(5):1237-9
COMVAX  0   *Hepatitis B Vaccines *Haemophilus Vaccines Vaccines, Synthetic Vaccines, Conjugate. MMWR Morb Mortal Wkly Rep 1997 Feb 7;46(5):107-9
transmission-Blocking Vaccine based on Pfs25  0   *Recombinant Proteins *Protozoan Proteins Antigens, Protozoan Vaccines, Synthetic Malaria Vaccines. Ann N Y Acad Sci 1996 May 15;782:123-32
(NANP)19-5.1  0   *Protozoan Vaccines Vaccines, Synthetic Antigens, Protozoan. Trop Geogr Med 1995;47(2):61-3
Theradigm-HBV  0   *Peptide Fragments *Lipopeptides Vaccines, Synthetic Hepatitis B Vaccines. J Clin Invest 1995 Jan;95(1):341-9
HIV-1 IIIB gp120 subunit vaccine  0   *HIV Envelope Protein gp120 *AIDS Vaccines Vaccines, Synthetic. Lancet 1993 Jul 10;342(8863):69-73
D protein, influenza A (A-PR-8-34-derived recombinant protein)  0   *Influenza Vaccines Vaccines, Synthetic. J Infect Dis 1993 Mar;167(3):593-601
adenovirus 5, rabies glycoprotein recombinant vaccine  0   *Rabies Vaccines Vaccines, Synthetic. Can J Vet Res 1992 Oct;56(4):360-4
Pre-S protein, Duck hepatitis B virus  0   *Viral Envelope Proteins Vaccines, Synthetic Hepatitis B Virus, Duck. Chin Med J (Engl) 1992 Mar;105(3):199-203
Recombivax HB  0   *Hepatitis B Vaccines Vaccines, Synthetic.
Engerix-B  0   *Hepatitis B Vaccines Vaccines, Synthetic.
glycoprotein gp70, Feline leukemia virus  0   *Viral Envelope Proteins *Retroviridae Proteins, Oncogenic Vaccines, Synthetic Viral Vaccines. J Am Vet Med Assoc 1991 Nov 15;199(10):1423-7
R 32NS1(81)  0   *Malaria Vaccines Vaccines, Synthetic. Lancet 1991;337(8748):998
octopus construct 115-131  0   *Antigens, Helminth Vaccines, Synthetic. J Immunol 1991;146(6):1987
Salk HIV Immunogen  0   *AIDS Vaccines HIV Vaccines, Synthetic. Can Med Assoc J 1990;143(9):907
SPf66 protein, Plasmodium  0   *Recombinant Proteins *Protozoan Proteins Vaccines, Synthetic Malaria Vaccines. Am J Trop Med Hyg 1990;43(4):339
Ro 40-2361  135669-47-5   *Tetanus Toxoid *Protozoan Proteins Vaccines, Synthetic. Bull Soc Pathol Exot Filiales 1990;83(2):217
HibTITER protein, Haemophilus influenzae  126161-67-9 HibTITER  *Bacterial Proteins *Haemophilus Vaccines Vaccines, Synthetic. Contrib Microbiol Immunol 1989;10:125
VaxSyn HIV-1 (gp160) vaccine  0   *AIDS Vaccines HIV Vaccines, Synthetic HIV Envelope Protein gp160. JAMA 1987;258(11):1433
NP protein, Influenza A virus  0   *Viral Core Proteins *RNA-Binding Proteins Influenza A virus Viral Vaccines Vaccines, Synthetic. Immunogenetics 1986;23(6):379
3,6-di-O-methyl-beta-glucopyranosyl-(1-4)-2,3-di-O-methyl-alpha-rhamnopyranose  89821-88-5 alpha-L-Mannopyranose, 6-deoxy-4-O-(3,6-di-O-methyl-beta-D-glucopyranosyl)-2,3-di-O-methyl-, (2S-trans)  *Disaccharides Epitopes Antigens, Bacterial Haptens Vaccines, Synthetic. J Infect Dis 1984;150(3):311

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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