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Cladribine
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Definition
: An antineoplastic agent used in the treatment of lymphoproliferative diseases including hairy-cell leukemia.
Pharmacological Action
Antineoplastic Agents
;
Immunosuppressive Agents
Other names
2-
Chlorodeoxyadenosine; 2-
Chloro-
2'-
deoxyadenosine; Leustatin; 2'-
Deoxy-
2-
chloroadenosine
Drugs
*
:
CLADRIBINE
;
LEUSTATIN
Substance
CAS Registry & name
Categories
Source
Drugs
*
EC regimen 2
0
*Antineoplastic Combined Chemotherapy Protocols
Etoposide
Cladribine.
Chemotherapy 2005 Aug;51(5):247-51
CMC protocol 2
0
*Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Mitoxantrone
Cladribine.
Eur J Haematol 2001 Mar;66(3):188-94
CLAG protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Granulocyte Colony-Stimulating Factor
Cladribine.
Leuk Lymphoma. 2000 Sep;39(1-2):121-9
CMD protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Dexamethasone
Mitoxantrone
Cladribine.
Leuk Lymphoma 1999 Jan;32(3-4):359-63
cladribine triphosphate
0
Adenosine Triphosphate/*analogs & derivatives
Cladribine/*analogs & derivatives
Ribonucleotide Reductases/antagonists & inhibitors.
Blood 1996 Jan 1;87(1):256-64
5'-
chloro-
5'-
deoxyadenosine
892-48-8
*Cladribine
Isomerism.
J Biol Chem 1985;260(6):3469