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Migraine Disorders

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Definition: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)  note many specifics; use word of text   
Examples Migraine with Aura; Migraine without Aura; Ophthalmoplegic Migraine 		Other names Status Migrainosus; Headache, Migraine; Acute Confusional Migraine; Variants, Migraine; Variant, Migraine; Sick Headaches; Migraines, Hemicrania; Migraines, Acute Confusional; Migraines, Abdominal; Migraines; Migraine, Hemicrania; Migraine, Acute Confusional; Migraine, Abdominal; Migraine Variants; Migraine Syndromes, Cervical; Migraine Syndrome, Cervical; Migraine Headaches; Migraine Disorder; Hemicrania Migraines; Headaches, Sick
 
SubstanceCAS Registry & nameCategoriesSource
Hemiplegic migraine, familial type 1  0   *Cerebellar Ataxia *Migraine Disorders.
Indoprocaf  0   *Caffeine *Indomethacin *Prochlorperazine Drug Combinations Migraine Disorders. Int J Clin Pract. 2007 Aug;61(8):1256-69
7-(1-(4-chlorophenoxy)ethyl)-1,2,4-trazolo(1,5-alpha)pyrimidine  0   *Pyrimidines Migraine Disorders. CNS Drug Rev 2001 Summer;7(2):146-71
almotriptan  154323-57-6   *Tryptamines Migraine Disorders.
Pharma Action Serotonin Receptor Agonists 		Clin Pharmacol ther 2000 May;67(5):498-503ALMOTRIPTAN MALATE; AXERT
3-(3,4,5-trimethoxybenzoyloximino)-8-methyl-8-azabicyclo(3,2,1)octane  0   *Aza Compounds *Bicyclo Compounds, Heterocyclic Migraine Disorders. Eksp Klin Farmakol 1998 May-Jun;61(3):28-31
frovatriptan  0   *Carbazoles *Tryptamines Migraine Disorders.
Pharma Action Serotonin Receptor Agonists 		J Cardiovasc Pharmacol 1997 Jul;30(1):136-41FROVA
rizatriptan  145202-66-0   *Triazoles *Tryptamines Migraine Disorders.
Pharma Action Serotonin Receptor Agonists 		J Med Chem 1995 May 12;38(10):1799-810MAXALT; MAXALT-MLT; RIZATRIPTAN BENZOATE
KB 2796  101477-54-7   *Piperazines Migraine Disorders.
Pharma Action Calcium Channel Blockers 		Nippon Geka Hokan 1986;55(5):682
nicotinoyl-GABA  34562-97-5   gamma-Aminobutyric Acid/*analogs & derivatives Migraine Disorders.
Pharma Action Analgesics ; Antioxidants ; Nootropic Agents 		Chem Pharm Bull (Tokyo) 1984;32(10):4089
trichlorosucrose  56038-13-2 alpha-D-Galactopyranoside, 1,6-dichloro-1,6-dideoxy-beta-D-fructofuranosyl 4-chloro-4-deoxy  Sucrose/*analogs & derivatives Migraine Disorders.
Pharma Action Sweetening Agents 		Arch Oral Biol 1979;24(12):965
tolfenamic acid  13710-19-5   *Anthranilic Acids Migraine Disorders/drug therapy.
Pharma Action Analgesics ; Anti-Inflammatory Agents, Non-Steroidal ; Calcium Channel Blockers ; Prostaglandin Antagonists ; Serotonin Antagonists 		Acta Obstet Gynecol Scand (Suppl) 87:73;1979; Arzneim Forsch 25(7):1082;1975; Eur J Clin Pharmacol 13(5):331;1978; Lancet 2(8086):393;1978; Lancet 2(8138):326;1979; Prostaglandins 1979;18(4):655; Scand J Rheumatol (Suppl) 20:1;1977; Scand J Rheumatol (Suppl) 24:5;1979; Scand J Rheumatol (Suppl) 24:9;1979
migraleve  78168-90-8 Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)-, phosphate (1-1) (salt), mixture with sodium 1,4-bis(2-ethylhexyl) sulfobutanedioate, 1-((4-chlorophenyl)phenylmethyl)-4-((4-(1,1-dimethylethyl)phenyl)methyl)piperazine dihydr  *Acetaminophen *Codeine *Succinates Drug Combinations Migraine Disorders/drug therapy. Curr Ther Res 18(1):222;1975; Practitioner 211(1263):357;1973
flumedroxone  15687-21-5 17- acetyloxy-6 alpha-(trifluoromethyl)preg-4-ene,3,20-dione  *Hydroxyprogesterones Migraine Disorders/drug therapy. Acta Pharm Suec 15(3):233;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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