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Lidocaine

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Definition: A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of procaine but its duration of action is shorter than that of bupivacaine or prilocaine.     
Pharmacological Action Anesthetics, Local; Anti-Arrhythmia Agents 		Other names Lignocaine; Monohydrochloride, Lidocaine; Monohydrate Lidocaine Monohydrochloride; Monoacetate, Lidocaine; Hydrochloride, Lidocaine; Hydrocarbonate, Lidocaine; Carbonate, Lidocaine; 2 2EtN 2MePhAcN; Xyloneural; Xylocitin; Xylocaine CO2; Xylocaine; Xylesthesin; Octocaine; Lidocaine Sulfate (1:1); Lidocaine Monohydrochloride, Monohydrate; Lidocaine Monohydrochloride; Lidocaine Monoacetate; Lidocaine Hydrochloride; Lidocaine HydrocarbonateDrugs* : XYLOCAINE 1.5% W/ DEXTROSE 7.5%; XYLOCAINE PRESERVATIVE FREE; LIDOCAINE HYDROCHLORIDE 0.4% AND DEXTROSE 5% IN PLASTIC CONTAINER; LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE; ALPHACAINE; LARYNG-O-JET KIT; LIDOCAINE HYDROCHLORIDE 0.1% AND DEXTROSE 5% IN PLASTIC CONTAINER; LIDOCAINE HYDROCHLORIDE PRESERVATIVE FREE IN PLASTIC CONTAINER; LTA II KIT; LIDOCAINE HYDROCHLORIDE IN PLASTIC CONTAINER; XYLOCAINE; LIDOCAINE HYDROCHLORIDE; ZINGO; LIDOCAINE HYDROCHLORIDE VISCOUS; LIDOCAINE; LIDOCAINE HYDROCHLORIDE 0.4% IN DEXTROSE 5%; ANESTACON; LIDOCAINE HYDROCHLORIDE 0.2% IN DEXTROSE 5%; LIDOCATON; PEDIATRIC LTA KIT
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
TAC Alternate  0   *Lidocaine *Phenylephrine *Tetracaine Drug Combinations Anesthetics, Local Anesthetics, Combined. J Am Dent Assoc. 2007 Oct;138(10):1333-9.
ivory wave  0   *Lidocaine *Pyrrolidines *Benzodioxoles Drug Combinations Street Drugs. Emerg Med J. 2011 Dec;28(12):1059-60.
JMF2-1 compound  0   Lidocaine/*analogs & derivatives. Clin Exp Allergy. 2011 Feb;41(2):250-9
visthesia  0   *Hyaluronic Acid *Lidocaine. BMC Ophthalmol 2011;11:9
Antrolin  0   *Lidocaine *Nifedipine Drug Combinations. Can J Surg. 2010 Feb;53(1):17-24
phenylephrine, lidocaine drug combination  0   *Lidocaine *Phenylephrine Drug Combinations. J Laryngol Otol. 2009 Jun;123(6):626-30
Proliferol  0   *Glucose *Glycerol *Lidocaine *Phenol Drug Combinations. Int J Toxicol. 2009 May-Jun;28(3):219-29
Strepsils  0   *Lidocaine. Vestn Otorinolaringol 2007;(5):60-1
Lidoderm  0   *Lidocaine. LIDODERM
lidocaine-polyacrylate  0   *Acrylic Resins Lidocaine/*analogs & derivatives. J Pharm Sci. 2005 Sep;94(9):2039-48
S-Caine Peel  0   *Lidocaine *Tetracaine Drug Combinations. Lasers Surg Med 2004;34(5):446-50LIDOCAINE AND TETRACAINE; SYNERA
Phaedpharm  0   *Lidocaine *Phenylephrine. Laryngoscope 2004 Jun;114(6):1060-2
LET, anesthetic  0   *Epinephrine *Lidocaine *Tetracaine. Pediatrics 1998 Apr;101(4 Pt 1):730-1
tonicaine  0   Lidocaine/*analogs & derivatives. Anesthesiology 1995 Dec;83(6):1293-301
L 30  21236-52-2   Lidocaine/*analogs & derivatives Sodium Channels. J Cardiovasc Pharmacol 1994 Nov;24(5):803-12
RAD 243  103825-20-3   Lidocaine/*analogs & derivatives Sodium Channels. J Cardiovasc Pharmacol 1994 Nov;24(5):803-12
RAD 244  60108-67-0   Lidocaine/*analogs & derivatives Sodium Channels. J Cardiovasc Pharmacol 1994 Nov;24(5):803-12
lignocaine copper(II) complex  0   *Lidocaine *Organometallic Compounds Copper. J Pharm Biomed Anal 1994 Sep;12(9):1209-13
3-hydroxy-monoethylglycinexylidide  34604-56-3   Lidocaine/*analogs & derivatives. Transplant Proc 1994 Dec;26(6):3293-4
Ligenten  0   *Quaternary Ammonium Compounds *Gentamicins *Lidocaine Drug Combinations Gels. Urol Nefrol (Mosk) 1994 May-Jun;(3):14-7
perinal  0   *Hydrocortisone *Lidocaine Drug Combinations. Int J Colorectal Dis 1993 Dec;8(4):184-7
3-hydroxylidocaine  34604-55-2   Lidocaine/*analogs & derivatives. J Pharm Sci 1992 Mar;81(3):265-71
neolidocatone  0   Lidocaine/*analogs & derivatives. Cesk Otolaryngol 1990;39(4):221
dexpanthenol, lidocaine, prednisolone, triclosan drug combination  0   *Lidocaine *Prednisolone *Triclosan Drug Combinations Pantothenic Acid/*analogs & derivatives. Vestn Dermatol Venerol 1989;(9):66
RAD 242  103825-19-0   Lidocaine/*analogs & derivatives. Circ Res 1989;65(5):1247
Neriproct  117803-69-7 Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11-hydroxy-16-methyl-21-((1-oxopentyl)oxy)-, (6alpha,11beta,16alpha)-, mixt. with 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide  *Diflucortolone *Lidocaine Drug Combinations. Nippon Yakurigaku Zasshi 1988;92(4):227
transcainide  88296-62-2   Lidocaine/*analogs & derivatives. Eur J Pharmacol 1987;135(1):41
2-(dimethylamino)-N-(2,6-dimethylphenyl)acetamide  21236-54-4   Lidocaine/*analogs & derivatives. Br J Anaesth 1987;59(3):379
Reboul cocktail  117706-64-6   *Lidocaine *Penicillins *Tetracyclines *Tolazoline Drug Combinations. J Mal Vasc 1986;11(4):388
W 6211  22759-46-2   Lidocaine/*analogs & derivatives. J Pharmacol Exp Ther 1986;238(1):159
lignocaine N-oxide  2903-45-9   Lidocaine/*analogs & derivatives. J Pharm Pharmacol 1986;38(4):326
omega-diethylamino-2-hydroxymethyl-6-methylacetanilide  0   Lidocaine/*analogs & derivatives. Drug Metab Dispos 1986;14(2):277
ethylmethylglycinexylidide  74634-66-5 Acetamide, N-(2,6-dimethylphenyl)-2-(ethylmethylamino)-, (Z)  Lidocaine/*analogs & derivatives. Clin Biochem 1984;17(4):230
lidocaine ethiodide  85708-79-8   Lidocaine/*analogs & derivatives. J Physiol (Lond) 1984;352:653
pilsicainide  88069-49-2   Lidocaine/*analogs & derivatives.
Pharma Action Anti-Arrhythmia Agents ; Sodium Channel Blockers 		Naunyn Schmiedebergs Arch Pharmacol 1984;326(2):163
lidocaine, norepinephrine, vasopressin drug combination  0   *Lidocaine *Norepinephrine *Vasopressins. Schweiz Monatsschr Zahnmed 1984;94(4):307
IQB-M 81  83471-41-4   *Azepines Lidocaine/*analogs & derivatives. Eur J Pharmacol 1983;95(1-2):93
EMLA  0   *Lidocaine *Prilocaine Ointments.
Pharma Action Anesthetics, Local ; Oxidants ; Anesthetics, Combined 		Acta Anesthesiol Scand 1982;26(6):596EMLA; ORAQIX; LIDOCAINE AND PRILOCAINE
Socketol  81340-57-0 Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-, mixt. with 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide  *Lidocaine *Prednisolone Drug Combinations Administration, Topical. Dtsch Zahnaerztl Z 1981;36(10):667
TDZ (hemostatic)  0   *Aluminum *Cetylpyridinium *Lidocaine Drug Combinations. Dent Outlook 1980;55(5):943
methyl nitrile lidocaine analog  70121-34-5 Acetamide, N-(3-cyano-4,5-dimethyl-1H-pyrrol-2-yl)-2-(diethylamino)-, monohydrochloride  Lidocaine/*analogs & derivatives. Pharmacology 1979;19(1):36
Levorenone  54958-67-7 Acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-, mixt. with (R)-4-(1-hydroxy-2-(methylamino)ethyl)-1,2-benzenediol  *Epinephrine *Lidocaine Drug Combinations. Bull Soc Belge Ophtalmol 1979;185:99LIGNOSPAN STANDARD; LIGNOSPAN FORTE
pyrrocaine  2210-77-7 N-(2,6-dimethylphenyl)-1-pyrrolidineacetamide  Lidocaine/*analogs & derivatives. Chir Dent Fr 49(29):49;1979
benzylcarbamyllidocaine  72406-72-5 1H-Pyrrole-3-carboxamide, 2-(((diethylamino)acetyl)amino)-4-methyl-5-(phenylmethyl)-, monohydrochloride  Lidocaine/*analogs & derivatives. Pharmacology 1979;19(1):36
benzyl nitrile lidocaine analog  70121-39-0 Acetamide, N-(3-cyano-4-methyl-5-(phenylmethyl)-1H-pyrrol-2-yl)-2-(diethylamino)-, monohydrochloride  Lidocaine/*analogs & derivatives. Pharmacology 1979;19(1):36
Panotile  99401-18-0 Pregn-4-ene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-, (11beta)-, mixt. with alkylbenzyldimethylammonium chlorides, 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide, neomycin sulfate (salt) and polymyxin B sulfate (salt)  *Benzalkonium Compounds *Lidocaine *Neomycin *Polymyxin B Drug Combinations Fludrocortisone/*analogs & derivatives. Rev Laryngol Otol Rhinol 99(11-12):765;1978
Dixidextracaine-70  72214-54-1 Dextran, mixt. with 2-butoxy-N-(2-(diethylamino)ethyl)-4-quinolinecarboxamide and 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide  *Dibucaine *Lidocaine Drug Combinations. Prakt Anaesth 14(1):71;1979
lidocaine iminodiacetic acid  62605-94-1   *Lidocaine Drug Combinations Glycine/*analogs & derivatives. Int J Nucl Med Biol 4(2):122;1977
N-methyllidocaine  29199-61-9   Lidocaine/*analogs & derivatives. J Pharmacol Exp Therap 201(1):184;1977
tribenoside (combination)  78940-02-0 D-Glucofuranoside, ethyl 3,5,6-tris-O-(phenylmethyl)-, mixt. with 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide  *Glycosides *Lidocaine Drug Combinations. Vestn Khir 9:46;1976
QX-314  21306-56-9 2-((2,6-dimethylphenyl)amino)-N,N,N-triethyl-2-oxoethanaminium  Lidocaine/*analogs & derivatives.
Pharma Action Anesthetics, Local 		Biophys J 23(2):285;1978; Biophys J 24(2):569;1978; J Physiol (Lond) 258(2):279;1976; J Physiol (Lond) 277:153;1978
W 12099  25027-88-7 acetamide, 2-((2-chloroethyl)ethylamino)-N-(2,6-dimethylphenyl)-, monohydrochloride  Lidocaine/*analogs & derivatives. Life Sci 18(8):821;1976
Doxiproct Plus  76404-12-1 Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-16-methyl-, (11beta,16alpha)-, mixt. with 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide and 2,5-dihydroxybenzenesulfonic acid calcium salt (2:1)  *Calcium Dobesilate *Dexamethasone *Lidocaine Drug Combinations. Praxis 64(10):299;1975
Doxiproct  76404-11-0 Benzenesulfonic acid, 2,5-dihydroxy-, calcium salt (2:1), mixt. with 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide  *Calcium Dobesilate *Lidocaine Drug Combinations. Praxis 64(10):299;1975
GEA 968  50333-29-4 N,N-diethylglycyl-N-(2,6-dimethylphenyl)glycinamide  Lidocaine/*analogs & derivatives. J Pharmacol Exp Ther 195(2):25;1975
chlorhexidine gluconate, lidocaine drug combination  8060-72-8 D-Gluconic acid, compd. with N,N''-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide (2:1), mixt. with 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide monohydrochloride  *Chlorhexidine *Lidocaine Drug Combinations. Int Urol Nephrol 4(1):48;1972
N,N-bis(phenylcarbamoylmethyl)dimethylammonium chloride  1042-42-8 N,N-dimethyl-2-oxo-N-(2-oxo-2-(phenylamino)ethyl)-2-(phenylamino)ethanaminium, chloride  Lidocaine/*analogs & derivatives. Acta Med Scand 204(4):311;1978; Acta Med Scand Suppl 569:1;1974; Biophys J 23(2):285;1978; Cardiovasc Res 9(1):91;1975; Dokl Akad Nauk SSSR 244(6):1266;1979; Eur J Clin Pharmacol 8(3):277;1975; J Pharm Sci 64(2):359;1975
QX-222  21236-55-5 2-((2,6-dimethylphenyl)amino)-N,N,N-trimethyl-2-oxoethanaminium  Lidocaine/*analogs & derivatives. Biophys J 23(2):285;1978; J Physiol 1979;295:7P; J Physiol 258(2):279;1976; J Physiol 277:153;1978; Mol Pharmacol 1979;15(3):565; Proc Natl Acad Sci USA 71(11):4457;1974
Dona 200  8075-86-3 2-amino-2-deoxy-D-glucose hydriodide, mixt. with 2-amino-2-deoxy-D-glucose hydrochloride, 2-amino-2-deoxy-D-glucose sulfate (salt) & 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide monohydrochloride  *Glucosamine *Lidocaine Drug Combinations. Arch Int Pharmacodyn Ther 192(2):279;1971
Otipax  0   *Aminopyrine *Lidocaine Drug Combinations.
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