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Nifedipine

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Definition: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.     
Pharmacological Action Calcium Channel Blockers; Tocolytic Agents; Vasodilator Agents 		Other names Nifedipine Pfizer Brand; Nifedipine Orion Brand; Nifedipine KRKA Brand; Nifedipine GTIS; Nifedipine Bayer Brand; Monohydrochloride, Nifedipine; Bay1040; Bay 1040; BAYa1040; BAY a 1040; Vascard; Procardia XL; Procardia; Pfizer Brand of Nifedipine; Orion Brand of Nifedipine; Nifedipine-GTIS; Nifedipine Monohydrochloride; Nifangin; Korinfar; KRKA Brand of NifedipineDrugs* : PROCARDIA XL; ADALAT CC; ADALAT; PROCARDIA; AFEDITAB CR; NIFEDIPINE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
diethyl 1,4-dihydro-4-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)-2,6-dimethylpyridine-3,5-dicarbo-xylate  0   Nifedipine/*analogs & derivatives. Chem Biol Drug Des. 2011 Nov;78(5):881-6.
diethyl 1,4-dihydro-4-(3-(4-bromophenyl)-1-phenyl-1H-pyrazol-4-yl)-2,6-dimethyl pyridine-3,5-dicarboxylate  0   Nifedipine/*analogs & derivatives. Chem Biol Drug Des. 2011 Nov;78(5):881-6.
dimethyl 1,4-dihydro-4-(3-(4-nitrophenyl)-1-phenyl-1H-pyrazol-4-yl)-2,6-dimethylpyridine-3,5-dicarboxylate  0   Nifedipine/*analogs & derivatives. Chem Biol Drug Des. 2011 Nov;78(5):881-6.
Antrolin  0   *Lidocaine *Nifedipine Drug Combinations. Can J Surg. 2010 Feb;53(1):17-24
nitrosonifedipine  0   *Nitroso Compounds Nifedipine/*analogs & derivatives. J Pharmacol Sci 2009 Jan;109(1):14-9
2-(2-(2-(2-chloro-4-(6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenoxy)acetylamino)ethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester  0   Nifedipine/*analogs & derivatives. J Pharmacol Exp Ther 2005 Feb;312(2):517-24
PPK-5  0   Nifedipine/*analogs & derivatives. Mol Pharmacol 2002 Mar;61(3):649-58
PPK-12  0   Nifedipine/*analogs & derivatives. Mol Pharmacol 2002 Mar;61(3):649-58
1,4-dihydro-2,6-dimethyl--4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl-1-methylethyl ester  0   Nifedipine/*analogs & derivatives. Pharmacol Res 2001 Aug;44(2):113-6
1,4-dihydro-2,6--dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(2-cyanoethyl) ester  0   Nifedipine/*analogs & derivatives. Pharmazie 2000 Oct;55(10):747-50
OPC 13463  73372-63-1   *Nicotinic Acids Nifedipine/*analogs & derivatives. Drug Metab Dispos 1999 Feb;27(2):303-8
dehydronifedipine  0   Nifedipine/*analogs & derivatives. J Chromatogr B Biomed Sci Appl 1998 Dec 11;720(1-2):119-28
menidipine  0   Nifedipine/*analogs & derivatives. Chung Kuo Yao Li Hsueh Pao 1996 May;17(3):235-8
dibudipine  0   Nifedipine/*analogs & derivatives. J Pharm Pharmacol 1997 Dec;49(12):1229-33
mebudipine  0   Nifedipine/*analogs & derivatives. J Pharm Pharmacol 1997 Dec;49(12):1229-33
YM 430  0   Nifedipine/*analogs & derivatives. Jpn J Pharmacol 1997 Feb;73(2):113-24
CD 832  0   Niacinamide/*analogs & derivatives Nifedipine/*analogs & derivatives. Cardiovasc Drugs Ther 1993 Apr;7(2):265-71
nifedipine-co-dergocrine combination  0   *Ergoloid Mesylates *Nifedipine Drug Combinations. Eur J Drug Metab Pharmacokinet 1992 Jan-Mar;17(1):33-8
Depin-E  131715-56-5 Depin E  Nifedipine/*analogs & derivatives. Klin Med (Mosk) 1990;68(6):85
MPC 2101  86781-07-9   Nifedipine/*analogs & derivatives. Arch Int Pharmacodyn Ther 1988;296:101
DHM 9  104305-95-5   Nifedipine/*analogs & derivatives. Br J Pharmacol 1988;94(4):1275
BAY-P 8857  97856-31-0   Nifedipine/*analogs & derivatives Iodine Radioisotopes. Life Sci 1986;39(25):2401
KW 3049  85387-35-5   Nifedipine/*analogs & derivatives.
Pharma Action Calcium Channel Blockers 		Nippon Yakurigaku Zasshi 1986;88(3):179
mepirodipine  104713-75-9   Nifedipine/*analogs & derivatives.
Pharma Action Calcium Channel Blockers 		J Med Chem 1986;29(12):2504
2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid  88434-67-7   Nifedipine/*analogs & derivatives. Farmakol Toksikol 1986;49(3):78
1,4-dihydro-2,6-dimethyl-4--(3-nitrophenyl)pyridine-3-carboxylic acid-5-carboxylic methyl ester  74936-72-4   Nifedipine/*analogs & derivatives. Biochem Biophys Res Commun 1986;134(2):922
YC 170  59946-73-5 3-Pyridinecarboxylic acid, 4-(2-chlorophenyl)-1,4-dihydro-2,6-dimethyl-5-((phenylamino)carbonyl)-, 2-(2-pyridinyl)ethyl ester  Nifedipine/*analogs & derivatives. Life Sci 1985;37(14):1271
ryodipine  71653-63-9   Nifedipine/*analogs & derivatives.
Pharma Action Anticonvulsants ; Antihypertensive Agents ; Calcium Channel Blockers ; Vasodilator Agents 		Arzneimittelforsch 1985;35(4):668
acebutolol, nifedipine drug combination  0   *Acebutolol *Nifedipine Drug Combinations.
Pharma Action Antihypertensive Agents 		Eur J Clin Pharmacol 1985;28(1):17
BAY-k 9320  74687-14-2   Nifedipine/*analogs & derivatives. Dtsch Med Wochenschr 1983;108(47):1795
mesudipine  62658-88-2   Nifedipine/*analogs & derivatives. J Cardiovasc Pharmacol 1983;5(1):162
dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate  67035-22-7   Nifedipine/*analogs & derivatives. J Chromatogr 1982;231(2):451
nilvadipine  75530-68-6 3,5-Pyridinedicarboxylic acid, 2-cyano-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-, 3-methyl 5-(1-methylethyl) ester  Nifedipine/*analogs & derivatives.
Pharma Action Antihypertensive Agents ; Calcium Channel Blockers 		Eur J Pharmacol 1982;80(1):149
darodipine  72803-02-2 3,5-Pyridinedicarboxylic acid, 4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-, diethyl ester  Nifedipine/*analogs & derivatives.
Pharma Action Calcium Channel Blockers 		J Cardiovasc Pharmacol 1982;4(3):344
1,4-dihydro-2,6-dimethyl-4-(2,4-dinitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester  21835-77-8 3,5-Pyridinedicarboxylic acid, 4-(2,4-dinitrophenyl)-1,4-dihydro-2,6-dimethyl-, dimethyl ester  Nifedipine/*analogs & derivatives. J Med Chem 1982;25(2):126
1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester  21829-09-4   Nifedipine/*analogs & derivatives. J Med Chem 1982;25(2):126
1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester  21881-77-6   Nifedipine/*analogs & derivatives. J Med Chem 1982;25(2):126
1,4-dihydro-2,6-dimethyl-4-(3-methylphenyl)-3,5-pyridinedicarboxylic acid dimethyl ester  80307-08-0 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-methylphenyl)-, dimethyl ester  Nifedipine/*analogs & derivatives. J Med chem 1982;25(2):126
1,4-dihydro-2,6-dimethyl-4-(4-methylphenyl)-3,5-pyridinedicarboxylic acid dimethyl ester  73257-48-4   Nifedipine/*analogs & derivatives. J Med Chem 1982;25(2):126
niludipin  22609-73-0   Nifedipine/*analogs & derivatives.
Pharma Action Calcium Channel Blockers 		Arzneim Forsch 1979;29(9):1368; Arzneim Forsch 1979;29(9):1373; Arzneim Forsch 29(2):226;1979; Arzneim Forsch 29(2):230;1979; Arzneim Forsch 29(2):246;1979
FR 7534  62760-70-7 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2-(hydroxymethyl)-6-methyl-4-(3-nitrophenyl)-, diethyl ester  Nifedipine/*analogs & derivatives. Eur J Pharmacol 54(3):289;1979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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