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Enzyme Activation

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Definition: Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme.  IM for general only; NIM with specific enzyme (IM); "enzyme reactivation": coord IM with specific enzyme /metab (IM) + ENZYME REACTIVATORS (IM) if discussed (see note there)    Other names Enzyme Activations; Activations, Enzyme; Activation, Enzyme
 
SubstanceCAS Registry & nameCategoriesSource
BssD protein, Thauera aromatica  EC 1.97.1.4   *Bacterial Proteins *Enzymes Enzyme Activation. Mol Microbiol 1998 May;28(3):615-28
glycyl-valyl-glutaminyl-seryl-leucyl-lysyl-arginyl-arginyl-arginyl-cysteinyl-phenylalanine  0   *Peptide Fragments *Viral Proteins Enzyme Activation. J Biol Chem 1997 Feb 28;272(9):5635-9
ecamulin  EC 3.4.24.-   *Metalloendopeptidases Enzyme Activation Viper Venoms Zinc. Biokhimiia 1996 Jun;61(6):1094-105
AMP-activated protein kinase kinase  EC 2.7.1.-   *Protein Kinases Enzyme Activation. Eur J Biochem 1994 Feb 1;219(3):751-7
PIK-A49 protein, Daucus carota  0   *Peptide Elongation Factors *Plant Proteins Enzyme Activation. J Biol Chem 1994 Feb 4;269(5):3852-7
HvrB protein, Rhodobacter capsulatus  0   *Bacterial Proteins *Enzyme Activation *Transcription Factors. J Bacteriol 1994 Jan;176(1):61-9
bryostatin 5  97850-04-9 Bryostatin 1, 20-O-acetyl-7-O-deacetyl-20-O-de(1-oxo-2,4-octadienyl)-7-O-(3-methyl-1-oxobutyl)  *Bryostatins Enzyme Activation. J Cell Biochem 1992 Aug;49(4):417-24
chymotrypsinogen A activating enzyme  EC 3.4.99.-   *Endopeptidases Enzyme Activation. Biochem Int 1991 Dec;25(6):1035-41
3-furfuryl-beta-glucoside  86425-28-7   *Furans *Glucosides Enzyme Activation. J Biol Chem 1991;266(21):13742
di(triethyleneglycoltetradecylether) phosphate  126223-50-5   *Phospholipids Enzyme Activation. Biochem Int 1989;19(6):1277
phospholipase A2-activating protein  0   *Proteins Enzyme Activation Phospholipases A.
Pharma Action Enzyme Activators 		Biochem J 1988;250(1):125
rca protein, plant  0   *Plant Proteins Enzyme Activation Molecular Chaperones. Proc Natl Acad Sci USA 1988;85(3):787
HMG-coenzyme A reductase activator protein, rat  EC 1.-   *Oxidoreductases Enzyme Activation. J Biol Chem 1987;262(35):17058
hydrogen potassium ATPase, gastric endogenous activator protein, mammal  0   *Gastrointestinal Hormones Enzyme Activation H(+)-K(+)-Exchanging ATPase. J Biol Chem 1987;262(12):5664
collagenase activator protein, Bos taurus  0   *Metalloproteases Enzyme Activation Peptide Hydrolases Collagenases. Arch Biochem Biophys 1986;251(2):715
galactosylceramide sulfatase activator protein, human  0   *Glycoproteins Enzyme Activation Galactosylceramidase. J Biochem (Tokyo) 1985;98(3):605
protein C activator peptide  0   *Oligopeptides Enzyme Activation Peptide Hydrolases Protein C. Ann Biol Clin (Paris) 1985;43(4):451
bryostatin 1  83314-01-6   *Bryostatins Enzyme Activation Mitogens.
Pharma Action Adjuvants, Immunologic ; Antineoplastic Agents 		Biochem Biophys Res Commun 1985;131(3):1109
DNA polymerase stimulatory protein, Epstein-Barr virus  0   *Viral Proteins DNA-Directed DNA Polymerase Enzyme Activation Herpesvirus 4, Human Neoplasm Proteins. Proc Natl Acad Sci USA 1985;82(17):5728
cerebroside sulfatase activator protein, human  0   *Proteins Enzyme Activation. J Biol Chem 1985;260(3):1867
pyruvate formate-lyase activating enzyme  0   *Enzymes Enzyme Activation Iron-Sulfur Proteins. Arch Biochem Biophys 1984;228(1):133
IMP dialdehyde  66672-00-2   Inosine Monophosphate/*analogs & derivatives Enzyme Activation. J Biol Chem 1981;256(12):5977
prothrombin activator (Taipan venom)  0   *Peptide Hydrolases *Prothrombin Elapid Venoms Enzyme Activation. Biochemistry 1980;19(5):1020
prephenoloxidase-activating enzyme  EC 3.4.21.-   *Serine Endopeptidases Enzyme Activation. Arch Biochem Biophys 157(1):203;1973; Ind J Biochem Biophys 12(2):210;1975; Ind J Biochem Biophys 12(2):89;1975
ecarin  EC 3.4.99.27   *Endopeptidases Enzyme Activation Viper Venoms.
Pharma Action Fibrinolytic Agents 		J Biochem (Tokyo):83(2):559;1978; J Biol Chem 254(18):8751;1879; Thromb Res 15(1-2):143;1979; Thromb Res 15(1-2):27;1979; Thromb Res 7(4):611;1975
phosphoenolpyruvate carboxykinase ferroactivator protein, rat  0   *Glutathione Peroxidase Enzyme Activation Phosphoenolpyruvate Carboxykinase (GTP). Biol Neonate 1979;36(5-6):311; J Biol Chem 252(1):116;1977; J Biol Chem 252(4):1431;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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