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Dehydroepiandrosterone

More information in Books or onNLM PubMed
Definition: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.     
Pharmacological Action Adjuvants, Immunologic
Examples Dehydroepiandrosterone Sulfate 		Other names Prasterone; Dehydroisoandrosterone; Prasterone, 3 alpha Isomer; 5 Androsten 3 ol 17 one; 5 Androsten 3 beta hydroxy 17 one; Prasterone, 3 alpha-Isomer; Androstenolone; DHEA; 5-Androsten-3-ol-17-one; 5-Androsten-3-beta-hydroxy-17-one
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
denosomin  0   Dehydroepiandrosterone/*analogs & derivatives Alzheimer Disease/drug therapy. Org Lett. 2009 Sep 3;11(17):3970-3
sominone  0   Dehydroepiandrosterone/*analogs & derivatives. Org Lett. 2009 Sep 3;11(17):3970-3
5-androstene-16alpha-fluoro-17-one  0   Dehydroepiandrosterone/*analogs & derivatives. Ann N Y Acad Sci. 2007 Sep;1110():630-40
HUM 5007  0   *Cholecalciferol *Ascorbic Acid *Nicotinic Acids *Plant Extracts Dehydroepiandrosterone/*analogs & derivatives. J Nutr Biochem 2007 Sep;18(9):629-34
3-acetyl-7-oxodehydroepiandrosterone  0   Dehydroepiandrosterone/*analogs & derivatives. J Nutr Biochem 2007 Sep;18(9):629-34
7alpha-amino-dehydroepiandrosterone  0   Dehydroepiandrosterone/*analogs & derivatives. Bioorg Med Chem 2007 May 1;15(9):3152-60
oleoyldehydroepiandrosterone  0   Dehydroepiandrosterone/*analogs & derivatives. BMC Pharmacol 2007;7:4
Andro-6  0   *Androstenedione *Dehydroepiandrosterone Drug Combinations. Skinmed 2006 Jan-Feb;5(1):46-7
dehydroepiandrosterone-bovine serum albumin  0   *Serum Albumin, Bovine Dehydroepiandrosterone/*analogs & derivatives. FASEB J 2006 Mar;20(3):577-9
3beta-acetoxyandrost-5-en-17-one  0   Dehydroepiandrosterone/*analogs & derivatives. Steroids. 2004 Mar;69(3):193-9
GL-701  0   Dehydroepiandrosterone/*analogs & derivatives Lupus Erythematosus, Systemic. Curr Opin Investig Drugs 2001 Feb;2(2):231-6
immunor  0   Dehydroepiandrosterone/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids 2000 Oct-Dec;19(10-12):2019-24
3-acetoxyandrost-5-ene-7,17-dione  0   Dehydroepiandrosterone/*analogs & derivatives. Biochem Biophys Res Commun 1999 Jan 8;254(1):120-3
3-(iodoacetoxy)dehydroisoandrosterone  0   Dehydroepiandrosterone/*analogs & derivatives Glutathione Transferase/antagonists & inhibitors. Arch Biochem Biophys 1997 Sep 1;345(1):16-31
dehydroepiandrosterone-7-O-(carboxymethyl)oxime  0   *Oximes Dehydroepiandrosterone/*analogs & derivatives. J Chromatogr B Biomed Appl 1997 Mar 28;691(1):187-91
fluasterone  156680-74-9   Dehydroepiandrosterone/*analogs & derivatives. J Natl Cancer Inst 1997 May 21;89(10):681-3
dehydroepiandrosterone phosphatide  0   *Phospholipids Dehydroepiandrosterone/*analogs & derivatives. Steroids 1995 Apr;60(4):333-6
3-(1,2-di-O-palmitoylglycero)sulfonylandrost-5-en-17-one  0   *Sulfones Dehydroepiandrosterone/*analogs & derivatives. Steroids 1995 Apr;60(4):321-3
3-(1,2-di-O-palmitoylglycero)sulfinylandrost-5-en-17-one  0   *Sulfoxides Dehydroepiandrosterone/*analogs & derivatives. Steroids 1995 Apr;60(4):321-3
3-(1,2-di-O-palmitoylglycero)thioandrost-5-en-17-one  0   Dehydroepiandrosterone/*analogs & derivatives. Steroids 1995 Apr;60(4):321-3
androst-5-en-17-one  6830-13-3   Dehydroepiandrosterone/*analogs & derivatives. Steroids 1995 Aug;60(8):499-505
dehydroepiandrosterone-3-O-methylthiophosphonate  155538-86-6   Dehydroepiandrosterone/*analogs & derivatives. J Steroid Biochem Mol Biol 1994 Apr;48(5-6):523-7
OH 8356  80724-82-9   Dehydroepiandrosterone/*analogs & derivatives HIV-1. AIDS Res Hum Retroviruses 1992 May;8(5):625-31
1-hydroxydehydroepiandrosterone  20998-18-9   Dehydroepiandrosterone/*analogs & derivatives. Chem Pharm Bull (Tokyo) 1992 Mar;40(3):648-51
Gynodian  81569-96-2 Androst-5-en-17-one, 3-((1-oxoheptyl)oxy)-, (3beta)-, mixt. with (17beta)-3-hydroxyestra-1,3,5(10)-trien-17-yl pentanoate  Dehydroepiandrosterone/*analogs & derivatives Drug Combinations Estradiol/*analogs & derivatives. Maturitas 1981;3(3-4):225
dehydroepiandrosterone enanthate  23983-43-9   Dehydroepiandrosterone/*analogs & derivatives. Maturitas 1981;3(3-4):225
dehydroepiandrosterone acetate  853-23-6   Dehydroepiandrosterone/*analogs & derivatives. Experientia 1980;36(11):1329
7-carboxymethyl dehydroepiandrosterone  0   Dehydroepiandrosterone/*analogs & derivatives. Steroids 1980;35(3):235
16-hydroxydehydroepiandrosterone sulfate  28905-55-7 androst-5-en-17-one, 3,16-dihydroxy-, mono(hydrogen sulfate), (3 beta,16 beta)  Dehydroepiandrosterone/*analogs & derivatives. J Clin Endocrinol Metab 1980;50(5):955
15-hydroxydehydroisoandrosterone  38391-29-6 Androst-5-en-17-one, 3,15-dihydroxy-, (3beta,15alpha)  Dehydroepiandrosterone/*analogs & derivatives. Steroids 31(5):613;1978
gonasterone  66457-02-1   *Dehydroepiandrosterone *Testosterone Drug Combinations. Jpn J Fertil Steril 22(4):266;1977
15 beta-carboxyethylmercaptodehydroepiandrosterone  75929-63-4 Propanoic acid, 3-(((3beta,15beta)-3-hydroxy-17-oxoandrost-5-en-15-yl)thio)  Dehydroepiandrosterone/*analogs & derivatives. Steroids 28(1):110;1976
16-hydroxydehydroepiandrosterone  1232-73-1 (3 beta,16 alpha)-3,16-dihydroxyandrost-5-en-17-one  Dehydroepiandrosterone/*analogs & derivatives. Am J Cardiol 38(6):805;1970; Am J Obstet Gynecol 132(4):392;1978; Ateneo Parmense 48(4):353;1977; Aust NZ J Obstet Gynaecol 1979;19(4):233; Clin Endocrinol (Tokyo) 24(3):245;1976; Endocrinol Jpn 1979;26(4):439; Endocrinol Sex Perinatol WK900 E56:259;1974; Experientia 32(8):1067;1976; Hormone Metab Res 8(4):302;1976; J Clin Endocrinol Metab 1980;50(3):489; J Clin Endocrinol Metab 43(5):1078;1976; J Clin Endocrinol Metab 44(4):629;1977; J Lab Clin Med 89(2):250;1977; J Steroid Biochem 6(5):752;1975; J Steroid Biochem 7(10):862;1976; J Steroid Biochem 7(5):419;1976; Proc Soc Exp Biol Med 152(2):218;1976; Steroids 27(6):797:1976; Steroids 27(6):845;1976; Steroids 29(1):17;1977
testosterone mustard  24141-90-0   *Nitrogen Mustard Compounds Dehydroepiandrosterone/*analogs & derivatives. Cancer Res 35(8):1975;1975
7-methoxydehydroepiandrosterone  0   Dehydroepiandrosterone/*analogs & derivatives.
7-hydroxydehydroepiandrosterone  53-00-9   Dehydroepiandrosterone/*analogs & derivatives. Steroids 26(1):1;1975; Steroids 30(3):315;1977; Steroids 31(1):113;1978
7-oxodehydroepiandrosterone  566-19-8 3 beta-hydroxyandrost-5-ene-7,17-dione  Dehydroepiandrosterone/*analogs & derivatives Receptors, GABA-A GABA Antagonists. Steroid Lipid Res 3(2):170;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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