ψ 
Glutathione Transferase 
A transferase that catalyzes the addition of aliphatic, aromatic, or heterocyclic FREE RADICALS as well as EPOXIDES and arene oxides to GLUTATHIONE. Addition takes place at the SULFUR. It also catalyzes the reduction of polyol nitrate by glutathione to polyol and nitrite.      Other names S-Hydroxyalkyl Glutathione Lyase; Ligandins; Glutathione S-Epoxidetransferase; Glutathione S-Aryltransferase; Glutathione S-Alkyltransferase; Transferase, Glutathione; Transferase mu, Glutathione; Transferase E, Glutathione; Transferases, Glutathione; Transfer Protein, Heme; S-Transferase, Glutathione; S-Transferase P, Glutathione; S-Transferase III, Glutathione; S-Transferase C, Glutathione; S-Transferase B, Glutathione; S-Transferase 3, Glutathione; Glutathione S Aryltransferase; Glutathione S Alkyltransferase; Glutathione S Epoxidetransferase; S-Transferase A, Glutathione
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
glutathione S-transferase M1  EC 2.5.1.18   *Glutathione Transferase.  Blood 1999 Mar 1;93(5):1496-501
glutathione S-transferase T1  EC 2.5.1.-   *Glutathione Transferase.  Pharmacogenetics 2000 Jun;10(4):301-9
Cibacron Blue F 3GA  12236-82-7 1-amino-4-((4-((4-chloro-6-((sulfophenyl)amino)- 1,3,5-triazin-2-yl)amino)-3-sulfophenyl)amino)- 9,10-dihydro-9,10-dioxo-2-anthracenesulfonic acid  *Triazines Glutathione Transferase/antagonists & inhibitors. 
Pharma Action Coloring Agents ; Enzyme Inhibitors ; Protein Synthesis Inhibitors
Acta Biol Med Ger 37(1):173;1978; Arch Biochem Biophys 185(2):433;1978; Arch Biochem Biophys 190(2):405;1978; Biochem Biophys Res Commun 1979;91(4):1462; Biochem Biophys Res Commun 82(2):745;1978; Biochem Biophys Res Commun 86(2):252;1979; Biochem J 157(2):301;1976; Biochem J 173(2):591;1978; Biochem J 175(2):501;1978; Biochemistry 17(20):4136;1978; Biochemistry 1979;18(23):5197; Biochemistry 1980;19(1):143; Biochim Biophys Acta 526(2):410;1978; Eur J Biochem 1979;102(1):107; Eur J Biochem 90(3):563;1978; Febs Lett 96(2):346;1978; J Biol Chem 252(11):3671;1977; J Biol Chem 252(16):5724;1977; J Immunol Methods 1979;30(2):119; J Mol Biol 1979;134(4):847
leukotriene-C4 synthase  EC 4.4.1.20   *Glutathione Transferase.  Arch Biochem Biophys 1984;230(2):455
URE2 protein, S cerevisiae  134773-68-5   *Prions *Saccharomyces cerevisiae Proteins Glutathione Transferase.  Mol Cell Biol 1991;11(2):822
glutathione S-transferase alpha  EC 2.5.1.18   *Glutathione Transferase *Isoenzymes.  Jpn J Cancer Res 1999 May;90(5):530-5
musk ketone  81-14-1   *Xylenes Glutathione Transferase Perfume Water Pollutants, Chemical. 
Pharma Action Antineoplastic Agents
Bull Environ Contam Toxicol 1981;26(5):656
GSTT2 protein, human  EC 2.5.1.-   *Glutathione Transferase. 
microsomal glutathione S-transferase- EC 2.5.1.-   *Glutathione Transferase.  Biochim Biophys Acta 1999 Sep 3;1446(3):389-96
GDAP protein  0   *Nerve Tissue Proteins Glutathione Transferase Glycoproteins Signal Transduction.  J Neurochem 1999 May;72(5):1781-90
maleylacetoacetate isomerase  EC 5.2.1.2   *cis-trans-Isomerases Glutathione Transferase.  J Biol Chem 248(1):215;1973
GSTA1 protein, human  EC 2.5.1.18   *Glutathione Transferase. 
GSTO1 protein, human  EC 2.5.1.18   *Glutathione Transferase.  Hum Mol Genet 2003 Dec 15;12(24):3259-67
GSTM3 protein, human  EC 2.5.1.18   *Glutathione Transferase.  Prostate. 2004 Mar 1;58(4):414-20
52-kDa protein, Trypanosoma cruzi  0   *Protozoan Proteins Glutathione Transferase.  Exp Parasitol 1995 Dec;81(4):453-61
GSTZ1 protein, human  EC 2.5.1.-   *Glutathione Transferase.  Pharmacogenetics 2000 Feb;10(1):49-57
glutathione transferase M2- EC 2.5.1.-   *Glutathione Transferase Isoenzymes.  Biochem Biophys Res Commun 2000 Jul 21;274(1):32-6
BZ2 protein, Zea mays  EC 2.5.1.18   *Plant Proteins Glutathione Transferase.  Plant Cell 1990 Nov;2(11):1039-49
GST-RAP protein, recombinant  0   *Carrier Proteins *Glutathione Transferase *Recombinant Fusion Proteins.  Circulation 1997 Jan 7;95(1):46-52
Gstz1 protein, rat  EC 2.5.1.-   *Glutathione Transferase. 
S-octylglutathione  24435-27-6   Glutathione/*analogs & derivatives Glutathione Transferase/antagonists & inhibitors.  Biochim Biophys Acta 1989;995(2):174
Gsto1 protein, mouse  0   *Carrier Proteins *Glutathione Transferase Heat-Shock Proteins.  J Biol Chem 1999 Feb 19;274(8):5131-7
benastatin A  138968-85-1 8,13-dihydro-1,7,9,11-tetrahydroxy-13-dimethyl-8-oxo-3-pentyl- benzo(a)naphthacene-2-carboxylic acid  *Naphthacenes Glutathione Transferase/antagonists & inhibitors.  J Antibiot (Tokyo) 1992 Sep;45(9):1391-6
Gstt2 protein, rat  EC 2.5.1.-   *Glutathione Transferase.  Biochem Biophys Res Commun 1994 Dec 15;205(2):1250-6
glutathione S-transferase 9.5- EC 2.5.1.-   *Glutathione Transferase *Isoenzymes.  Arch Biochem Biophys 1998 May 15;353(2):337-48
S-crystallin protein, Octopus  EC 2.5.1.-   *Crystallins *Glutathione Transferase.  Biophys J 1999 Feb;76(2):679-90
glutathione transferase M3- EC 2.5.1.18   *Glutathione Transferase Isoenzymes.  Neurochem Res 2000 May;25(5):733-6
GSTA1-1 protein, human  EC 2.5.1.18   *Glutathione Transferase.  J Biol Chem 2003 Oct 24;278(43):42283-93
GSTO2 protein, human  EC 2.5.1.18   *Glutathione Transferase.  Neurology 2004 May 25;62(10):1910-1
glutathione transferase T1-1, human  EC 2.5.1.18   *Glutathione Transferase.  Chem Res Toxicol 2003 Nov;16(11):1493-9
gamma-glutaminyl-S-(4-chlorobenzyl)cysteinyl-phenylglycine  152684-55-4   *Oligopeptides Glutathione Transferase/antagonists & inhibitors.  J Med Chem 1994 Jan 7;37(1):189-94
glutathione S-transferase 9.5- EC 2.5.1.-   *Glutathione Transferase *Isoenzymes.  Arch Biochem Biophys 1998 May 15;353(2):337-48
glutathione-BPDE conjugate  0   *Glutathione *7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide Glutathione Transferase/antagonists & inhibitors Stereoisomerism.  Biochem J 1998 Jun 15;332(Pt 3):799-805
GSTF2 protein, Arabidopsis  EC 2.5.1.18   *Glutathione Transferase *Arabidopsis Proteins.  Plant Cell Physiol 2003 Jul;44(7):750-7
GSTF8 protein, Arabidopsis  EC 2.5.1.18   *Glutathione Transferase *Arabidopsis Proteins.  Mol Plant Microbe Interact 2004 Jan;17(1):70-80
Gstz1 protein, mouse  EC 2.5.1.-   *Glutathione Transferase. 
SL-mercaptoethanol  89339-12-8 1-Pyrrolidinyloxy, 3-((((2-hydroxyethyl)thio)acetyl)amino)-2,2,5,5-tetramethyl-, (R)  *Cyclic N-Oxides Mercaptoethanol/*analogs & derivatives Glutathione Transferase/antagonists & inhibitors Spin Labels.  J Biol Chem 1984;259(2):714
GST-Nef protein, recombinant  0   *Glutathione Transferase *Recombinant Fusion Proteins *Gene Products, nef.  AIDS Res Hum Retroviruses 1994 Aug;10(8):1011-9
GstE1 protein, Drosophila  EC 2.5.1.-   *Glutathione Transferase *Drosophila Proteins.  Gene 2000 Apr 18;247(1-2):167-73
28 kDa gluthathione S-transferase antigen, Schistosoma haematobium  EC 2.5.1.-   *Antigens, Helminth *Glutathione Transferase *Helminth Proteins.  Clin Exp Immunol 2001 Apr;124(1):62-8
Gstm2 protein, mouse  EC 2.5.1.-   *Glutathione Transferase.  Gene 2001 May 30;270(1-2):221-9
glutathione S-transferase A3-3, human  EC 2.5.1.18   *Glutathione Transferase.  Biochemistry 2004 Dec 21;43(50):15673-9
9,10-dihydro-9-glutathionyl-10-hydroxyphenanthrene  84107-69-7   *Phenanthrenes Glutathione/*analogs & derivatives Glutathione Transferase/antagonists & inhibitors.  Biochem Biophys Res Commun 1986;141(3):892
TA 3037A  143651-44-9 2H-1,4-Benzoxazine-5-carboxylic acid, 3,4-dihydro-2-oxo-3-(phenylmethylene)-, (Z)  *Oxazines Glutathione Transferase/antagonists & inhibitors.  J Antibiot (Tokyo) 1992 Jul;45(7):1117-21
benastatin B  138968-86-2 5,6,8,13-tetrahydro-1,7,9,11-tetrahydroxy-13,13-dimethyl-8-oxo-3-pentylbenzo(a)naphthacene-2-carboxylic acid  *Naphthacenes Glutathione Transferase/antagonists & inhibitors.  J Antibiot (Tokyo) 1992 Sep;45(9):1391-6
W 77  118998-51-9 W 77  *Piperazines *Sulfonamides Glutathione Transferase/antagonists & inhibitors.  Cancer Res 1993 May 1;53(9):2051-6
3-cinnamyl-5-bromomethylidenetetrahydro-2-furanone  0   4-Butyrolactone/*analogs & derivatives Glutathione Transferase/antagonists & inhibitors.  J Biol Chem 1996 Aug 23;271(34):20421-5
glutathione S-transferase Yc  EC 2.5.1.-   *Glutathione Transferase.  Biochem J 1997 Apr 1;323( Pt 1):147-9
GSTU19 protein, Arabidopsis  EC 2.5.1.18   *Glutathione Transferase *Arabidopsis Proteins.  Plant Physiol 2002 Nov;130(3):1497-505
GSTF6 protein, Arabidopsis  EC 2.5.1.18   *Glutathione Transferase *Arabidopsis Proteins.  Plant Cell Physiol 2003 Jul;44(7):750-7
mGSTA4- EC 2.5.1.18   *Glutathione Transferase.  Toxicol Appl Pharmacol. 2004 Feb 1;194(3):296-308
28-kilodalton glutathione S-transferase antigen, Schistosoma mansoni  EC 2.5.1.18   *Antigens, Bacterial *Glutathione Transferase.  Clin Diagn Lab Immunol 2003 Jul;10(4):536-41
Gstt2 protein, mouse  EC 2.5.1.-   *Glutathione Transferase. 
GSTK1 protein, human  EC 2.5.1.18   *Glutathione Transferase.  J Biol Chem 2004 Apr 16;279(16):16246-53
tryptophan-dehydrobutyrine diketopiperazine  55062-34-5 2,5-Piperazinedione, 3-ethylidene-6-(1H-indol-3-ylmethyl)-1-methyl  Tryptophan/*analogs & derivatives Glutathione Transferase/antagonists & inhibitors.  J Antibiot (Tokyo) 27(10):733;1974
sulfobromophthalein-glutathione conjugase  EC 2.5.1.-   *Glutathione Transferase.  Clim Chim Acta 49(2):201;1973; Clin Chim Acta 47(2):133;1973; Ind J Med Res 64(7):1070;1976
SL-glutathione  89339-11-7 Glycine, N-(N-L-gamma-glutamyl-S-(2-oxo-2-((2,2,5,5-tetramethyl-1-oxy-3-pyrrolidinyl)amino)ethyl)-L-cysteinyl)-, (R)  *Cyclic N-Oxides Glutathione/*analogs & derivatives Glutathione Transferase/antagonists & inhibitors Spin Labels.  J Biol Chem 1984;259(2):714
1,2-diphenyl-1-(S-glutathionyl)-2-hydroxyethane  105449-15-8   Glutathione/*analogs & derivatives Glutathione Transferase/antagonists & inhibitors.  Biochem Biophys Res Commun 1986;141(3):892
S-(phenylsulfonyl)glutathione  97512-84-0   Glutathione/*analogs & derivatives Glutathione Transferase/antagonists & inhibitors.  Biochem J 1991;278(Pt 1:63
cyanocobalamin beta-ligand transferase  EC 2.5.1.-   *Glutathione Transferase.  Biochim Biophys Acta 1993 Jun 11;1157(2):167-77
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