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Butyrophenones
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Definition
: Compounds containing phenyl-1-butanone.
See Also
Antipsychotic Agents
Examples
Azaperone
;
Benperidol
;
Droperidol
;
Haloperidol
;
Spiperone
;
Trifluperidol
Substance
CAS Registry & name
Categories
Source
Drugs
*
4-
fluoro-
4-
(1,2,3,6-
tetrahydro-
1,3-
dimethyl-
2-
oxo-
6-
thionpurin-
8-
ylthio)butyrophenone
0
*Butyrophenones
*Purines
Estrogen Receptor alpha/antagonists & inhibitors.
J Biol Chem 2010 Dec 31;285(53):41863-73
4-
(4-
(4-
chlorophenyl)-
1,4-
diazepan-
1-
yl)-
1-
(4-
fluuorophenyl)butan-
1-
one
0
*Azepines
*Butyrophenones.
Bioorg Med Chem 2008 Aug 1;16(15):7291-301
4'-
hydroxymethyl-
alpha-
pyrrolidinobutyrophenone
0
*Butyrophenones
*Pyrrolidines.
Biochem Pharmacol 2007 Aug 1;74(3):511-20
desacetylsalannobutyrolactone
0
*Butyrophenones
*Heterocyclic Compounds with 4 or More Rings.
Fitoterapia. 2005 Dec;76(7-8):740-3
salannobutyrolactone
0
*Butyrophenones
*Heterocyclic Compounds with 4 or More Rings.
Fitoterapia. 2005 Dec;76(7-8):740-3
4'-
methyl-
alpha-
pyrrolidinobutyrophenone
0
*Butyrophenones
*Pyrrolidines.
J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Sep 25;824(1-2):81-91
hydroxyebastine
0
*Butyrophenones
*Piperidines.
J Chromatogr B Biomed Sci Appl 2001 Jun 5;757(1):173-9
4-
fluoro-
4(p-
nitrophenyl)-
2-
butanone
0
*Butyrophenones.
Biomol Eng 2001 Aug;18(1):1-7
4,4-
bis(4-
chlorophenyl)-
4-
hydroxypiperidinobutyrophenone
0
*Butyrophenones
*Piperidines.
Acta Pol Pharm 2000 Jan-Feb;57(1):23-6
4-
(4-
(4-
diphenylmethoxy-
1-
piperidyl)butyryl)dimethylphenylacetic acid
0
*Butyrophenones
*Piperidines.
Int J Clin Pharmacol Ther 1996 Dec;34(12):546-9
lenperone
24678-13-5
*Butyrophenones.
1-
(4-
fluorophenyl)-
4-
(4-
(5-
fluoro-
2-
pyrimidinyl)-
1-
piperazinyl)butan-
1-
one
133982-66-8
*Butyrophenones
*Pyrimidines.
Biotechnol Appl Biochem 1993 Apr;17(Pt 2):139-53
acetabutone
807-31-8
*Butyrophenones.
filicin
4482-83-1
*Butyrophenones
Plant Extracts.
Pharmacol Res Commun 1988; 20 Suppl 5:135
mobenzoxamine
65329-79-5
*Butyrophenones
*Piperazines.
Nippon Yakurigaku Zasshi 1988;92(5):297
carebastine
90729-42-3 Benzeneacetic acid, 4-
(4-
(4-
(diphenylmethoxy)-
1-
piperidinyl)-
1-
oxobutyl)-
alpha,alpha-
dimethyl
*Butyrophenones
*Piperidines.
Pharma Action
Histamine H1 Antagonists
;
Anti-Asthmatic Agents
Br J Clin Pharmacol 1988;26(5):497
ebastine
90729-43-4
*Butyrophenones
*Piperidines.
Pharma Action
Histamine H1 Antagonists
Br J Clin Pharmacol 1988;26(5):497
dihydrolenperone
38077-12-2
*Butyrophenones.
Cancer Treat Rep 1986;70(1):9
N-
(2-
(2-
butanoyl)-
4-
nitrophenoxyethyl)-
N,N-
bis(2-
chloroethyl)amine
92756-01-9 1-
Butanone, 1-
(2-
(2-
(bis(2-
chloroethyl)amino)ethoxy)-
5-
nitrophenyl)-
, (S-
(E))
*Butyrophenones
*Nitrogen Mustard Compounds.
J Pharm Sci 1984;73(8):1175
N,N-
bis(2-
(2-
butanoyl)-
4-
nitrophenoxyethyl)-
N-
(2-
chloroethyl)amine
92756-02-0 1-
Butanone, 1,1'-
(((2-
chloroethyl)imino)bis(2,1-
ethanediyloxy(5-
nitro-
2,1-
phenylene)))bis-
, (S-
(E))
*Butyrophenones
*Nitrogen Mustard Compounds.
J Pharm Sci 1984;73(8):1175
CIBA 3315A-
Go
0
*Butyrophenones.
J Assoc Physicians India 1982;30(7):433
timiperone
57648-21-2 4-
(4-
(2,3-
dihydro-
2-
thioxo-
1H-
benzimidazol-
1-
yl)-
1-
piperidinyl)-
1-
(4-
fluorophenyl)-
1-
butanone
*Butyrophenones.
Pharma Action
Antiemetics
;
Antipsychotic Agents
Eur J Pharmacol 59(3-4):245;1979
itanoxone
58182-63-1 2'-
chloro-
alpha-
methylene-
gamma-
oxo-
(1,1'-
biphenyl)-
4-
butanoic acid
*Butyrophenones.
J Pharm Sci 69(1):49;1980
67332MD
26964-71-6 1-
(4'-
fluorophenyl)-
4-
(cyclohexyl-
1'-
piperazinyl-
4'-
carboxylate)-
butane-
1-
one.HCl
*Butyrophenones.
Xenobiotica 7(5):315;1977
cloroperone
61764-61-2 1-
butanone, 4-
(4-
(4-
chlorobenzoyl)-
1-
piperdinyl)-
1-
(4-
fluorophenyl)
*Butyrophenones.
Drug Metab Dispos 4(6):562;1976; Prog Neuropsychopharmacol 2(1):117;1978
azabutyrone
2856-81-7
*Butyrophenones.
Anesteziol Reanimatol 5:35;1977; Farmakol Toksikol 39(1):59;1976; Farmakol Toksikol 39(4):402;1976; Farmakol Toksikol 39(5):517;1977; Farmakol Toksikol 41(2):154;1978; Farmakol Toksikol 41(3):289;1978; Farmatsiia 25(1):77;1976; Vestn Otorinolaringol 4:55;1977
U 35,777A
55199-71-8 4'-
fluoro-
4-
((4-
(p-
fluorophenyl)-
4-
methoxycyclohexyl)amino)butyrophenone.HCl
*Butyrophenones.
J Pharmacol 193(1):88;1975
ketocaine
1092-46-2 1-
butanone, 1-
(2-
(2-
(bis(1-
1-
methylethyl)amino)ethoxy)phenyl)
*Butyrophenones.
Acta Anesthesiol Scand 18(4):306;1974; Acta Pharm Suec 14(5-6):425;1977; Br J Anaesth 1979;51(12):1189; Br J Plast Surg 30:251;1977; Scand J Plast Reconstr Surg (Suppl) 11(1):79;1977; Scand J Plast Reconstructr Surg 11(1):79;1977
metylperon
3575-80-2 4'-
fluor-
4-
(4-
methylpiperidino)-
butyrophenone
*Butyrophenones
Anti-Arrhythmia Agents.
Pharma Action
Antipsychotic Agents
Acta Pharmacol Toxicol (Copenh) 42(5):388;1978; Acta Pharmacol Toxicol (Copenh) 43(2):129;1978; Acta Pharmacol Toxicol 38:145;1976; Arch Psychiatr Nervenkr 224:281;1977; Arzneim Forsch 1979;29(3):574; Eur J Pharmacol 49:285;1978; Farmaco (Prat) 29(10):586;1974; Int J Clin Pharmacol Biopharm 16(7):331;1978; Int J Clin Pharmacol Biopharm 1979;17(8):341; Naunyn Schmiedebergs Arch Pharmacol 304(1):27;1978; Pharmakopsychiatr Neuropsychopharmakol 11(2):86;1978; Pharmakopsychiatr Neuropsychopharmakol 1980;13(1):20; Psychopharmacologie 43(1):95;1975; Tidsk Nor Lageforen 95(23):1302;1975; Ugeskr Laeger 136(15):809;1974
centpyraquin
26049-76-3 3-
(gamma-
p-
fluorobenzoylpropyl)2,3,4,4a,5,6-
hexahydro-
1(H)-
pyrazino(1,2-
a)quinoline.HCl
*Butyrophenones.
Experientia 29(12):1529;1973
U-
32,802A
36735-48-5 4'-
fluoro-
4-
((4-
(p-
fluorophenyl)-
3-
cyclohexen-
1-
yl)-
amino)-
butyrophenone
*Butyrophenones.
Biochem Pharmacol 23(12):1701;1974; Br J Pharmacol 1979;67(1):115
pipamperone
1893-33-0
*Butyrophenones.
Pharma Action
Serotonin Antagonists
;
Antipsychotic Agents
Acta Psychiatr Belg 76(1):157;1976; Acta Psychiatr Belg 76(4):688;1976; Acta Psychiatr Belg 77:754;1977; Acta Psychiatr Belg 78(2):392;1978; Acta Psychiatr Scand 52(4):237;1975; Arch Int Pharmacodyn 217:280;1975
moperone
1050-79-9
*Butyrophenones.
fluanisone
1480-19-9 4'-
fluoro-
4-
(4-
(o-
methoxyphenyl)-
1-
piperazinyl)-
butyrophenone
*Butyrophenones.
Pharma Action
Hypnotics and Sedatives
;
Antipsychotic Agents
Encephale 4(2):145;1978; Lab Animals 9(3):161;1975
flavaspidic acid
114-42-1 3'-
((5-
butyryl-
2,4-
dihydroxy-
3,3-
dimethyl-
6-
oxo-