ψ 
ψ 
Bridged Compounds 
Cyclic hydrocarbons that contain multiple rings and share one or more atoms.  DF: BRIDGED CPDS    Other names Compounds, Bridged
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
taxane  1605-68-1   *Bridged Compounds *Taxoids. 
Pharma Action Antineoplastic Agents
Science 1993 Apr 9;260(5105):214-6
tricyclodecane-9-yl-xanthogenate  83373-60-8   *Bridged Compounds *Thiones Phospholipase C/antagonists & inhibitors Sphingomyelin Phosphodiesterase/antagonists & inhibitors. 
Pharma Action Antineoplastic Agents ; Antioxidants ; Antiviral Agents ; Phosphodiesterase Inhibitors
J Gen Virol 1985;66(Pt 9):1953
peoniflorin  23180-57-6 5b-((benzoyloxy)methyl)tetrahydro-5-hydroxy-2-methyl-2,5-methano-lH-3,4-dioxacyclobuta(cd) pentalen-1a(2H)-yl-beta-D-glucopyranoside  *Bridged Compounds *Glucosides *Benzoic Acids Paeonia. 
Pharma Action Anti-Inflammatory Agents, Non-Steroidal
J Pharm Sci Jpn 97(8):916;1977; Yakugaku Zasshi 1979;99(8):858; Yakugaku Zasshi 1980;99(6):598
tetramethylenedisulfotetramine  80-12-6 2,6-dithia- 1,3,5,7-tetraazatricyclo(3.3.1.1(3,7)-decane 2,2,6,6-tetraoxide)  *Bridged Compounds.  Br J Pharmacol 53(3):422;1975; Br J Pharmacol 53(4):598;1975; Br J Pharmacol 54(2):239;1975; Neuropharmacology 14(9):703;1975
enterocin  59678-46-5 3,6-Methanocyclopenta(c)pyran-1(3H)-one, 7-benzoylhexahydro-4a,6,7a,8-tetrahydroxy-5-(4-methoxy-2-oxo-2H-pyran-6-yl)-, (3R-(3alpha,4abeta,5alpha,6beta,7beta,7abeta,8R*))  Bridged Compounds.  J Antibiot (Tokyo) 29(10):1114;1976; J Antibiot (Tokyo) 29(3):227;1976
cucurbit(6)uril  80262-44-8   *Bridged Compounds *Imidazoles.  Org Lett 2002 Apr 18;4(8):1287-9
IDN 5109  0   *Bridged Compounds *Taxoids.  J Chromatogr B Biomed Sci Appl 1999 Dec 24;736(1-2):135-41
bornaprine  20448-86-6 2-phenylbicyclo(2.2.1)heptane-2-carboxylic acid, 3-(diethylamino)propyl ester  *Bridged Compounds.  Acta Neurol Scand 50(4):469;1974; Duodecim 90(8):590;1974
AR-R 17779  0   *Bridged Compounds *Spiro Compounds.  Behav Pharmacol 1999 Nov;10(6-7):675-80
sclerophytin A  0   *Bridged Compounds *Furans.  Org Lett 2000 Jun 29;2(13):1875-8
cucurbit(7)uril  0   *Bridged Compounds *Imidazoles.  Proc Natl Acad Sci U S A 2002 Apr 16;99(8):5007-11
SDZ NVI-085  104195-17-7 2H-Naphth(2,3-b)-1,4-oxazine, 3,4,4a,5,10,10a-hexahydro-6-methoxy-4-methyl-9-(methylthio)-, (4aR-trans)  *Bridged Compounds *Oxazines.  Eur J Pharmacol 1991 Nov 19;205(1):11-6
IDN 5390  0   *Bridged Compounds Taxoids.  Clin Cancer Res 2002 Apr;8(4):1182-8
7-hexanoyltaxol  0   *Bridged Compounds.  Circulation 2001 Jul 24;104(4):380-3
albiflorin  39011-90-0 9-((benzoyloxy)methyl)-1-(beta-D-glucopyranosyloxy)-4- hydroxy)-6-methyl-7-oxatricyclononan-8-one  *Bridged Compounds.  J Pharm Soc Jpn 97(8):916;1977
(2-chloro-5-pyridyl)-9-azabicyclo(4.2.1)non-2-ene  0   *Bridged Compounds *Pyridines.  J Neurosci 2000 Apr 15;20(8):2783-91
colombiasin A  0   *Bridged Compounds.  Org Lett 2000 Feb 24;2(4):507-10
NGP 1-01  33226-57-2 2,6,3,5-Ethanediylidenepentaleno(1,6-bc)pyrrol-2(1H)-ol, octahydro-1-(phenylmethyl)  *Bridged Compounds.  Pharmacol Res Commun 1986;18(5):407
RS 93427-007  105284-21-7   *Bridged Compounds Epoprostenol Prostaglandins, Synthetic.  Lancet 1986;2(8508):682
PD 140376  149027-97-4   *Bridged Compounds *Dipeptides.  Mol Pharmacol 1993 April;43(4):595-602
hexanitrohexaazaisowurzitane  135285-90-4   *Bridged Compounds *Nitro Compounds.  Free Radic Biol Med 1993 Sep;15(3):337-42
sclerophytin B  0   *Bridged Compounds *Furans.  Org Lett 2000 Jun 29;2(13):1879-82
BMS-275183  0   *Bridged Compounds.  Clin Cancer Res 2001 Jul;7(7):2016-21
5,6,9,10-tetrahydro-N,N-dimethyl-5,9-methanobenzocycloocten-11-amine  103064-23-9   *Bridged Compounds.  J Chromatogr 1986;377:205
paeonimetabolin I  99624-67-6   *Bridged Compounds.  Biol Pharm Bull 1997 May;20(5):517-21
kobusine  27530-78-5   *Bridged Compounds *Polycyclic Compounds.  Biol Pharm Bull 1998 Feb;21(2):140-6
sarain A  0   *Bridged Compounds.  Org Lett 1999 Dec 16;1(12):2017-9
uleine  0   *Alkaloids *Bridged Compounds.  Fitoterapia 2000 Apr;71(2):208-10
aphanorphine  0   Alkaloids *Bridged Compounds *Pyrroles.  Org Lett 2001 Aug 9;3(16):2427-9
bicyclo(3.3.1)nonane  0   *Bicyclo Compounds *Bridged Compounds.  Org Lett 2002 May 30;4(11):1943-6
Org 6582  59905-71-4   *Bridged Compounds.  Biochem Pharmacol 26(11):1083;1977; Biochem Pharmacol 27:1023;1978; Br J Pharmacol 56(3):367P;1976; Br J Pharmacol 59(3):481P;1977; Eur J Pharmacol 40:121;1976; Life Sci 22:1827;1978
treptilamine  58313-75-0 Ethanamine, N,N-diethyl-2-(phenyltricyclo(2.2.1.02,6)heptylidenemethoxy)-, hydrochloride  *Bridged Compounds *Ethylamines.  Arzneim Forsch 29(8):1189;1979
trichodimerol  0   *Bridged Compounds Tumor Necrosis Factor-alpha/antagonists & inhibitors.  J Antibiot (Tokyo) 1996 Mar;49(3):234-40
pseudokobusine  27901-01-5   *Bridged Compounds *Phenanthrenes.  Biol Pharm Bull 1998 Feb;21(2):140-6
ibogamine  0   *Bridged Compounds.  Org Lett 2000 Jul 27;2(15):2373-6
bisorbicillinol  0   *Bridged Compounds.  Biosci Biotechnol Biochem 2002 Oct;66(10):2090-9
bisorbicillinolide  0   *Bridged Compounds.  Biosci Biotechnol Biochem 2002 Oct;66(10):2090-9
mycoepoxydiene  0   *Bridged Compounds *Pyrones.  Org Lett. 2002 Aug 22;4(17):2941-3
acidrine  76157-56-7 D-Galactan, hydrogen sulfate, mixt. with 2-(2-(6,6-dimethylbicyclo(3.1.1)hept-2-en-2-yl)ethoxy)-N,N-diethylethanamine dodecyl sulfate and (T-4)-(glycinato-N,O)dihydroxyaluminum  *Bridged Compounds *Organometallic Compounds *Polysaccharides Drug Combinations Aluminum.  Lille Med 22(1-suppl 1):16;1976
punctaporonin D  102734-12-3   Bridged Compounds.  J Antibiot (Tokyo) 1986;39(1):167
5,6,9,10-tetrahydro-N-methyl-5,9-methanobenzocycloocten-11-amine  103064-24-0   *Bridged Compounds.  J Chromatogr 1986;377:205
caesalpin J  99217-67-1   *Bridged Compounds *Diterpenes Caesalpinia.  Chem Pharm Bull (Tokyo) 1986;34(10):4166
9,21-didehydroryanodol  106821-54-9   *Bridged Compounds.  Pflugers Arch 1996 Aug;432(4):700-7
isopinnatal  149471-07-8   *Anthraquinones *Bridged Compounds.  Planta Med 1996 Aug;62(4):352-3
WAY 132983  0   *Bridged Compounds *Pyrazines.  Bioorg Med Chem Lett 1999 Jul 19;9(14):1895-900
cladiell-11-ene-3,6,7-triol  0   *Bridged Compounds *Furans.  Org Lett 2001 Jan 11;3(1):135-7
solanoeclepin A  0   *Bridged Compounds *Hexanes.  J Org Chem 2001 Jan 12;66(1):233-42
ketopinic acid  0   *Bridged Compounds *Ketones.  Org Lett 2001 Jan 25;3(2):161-4
3-bromocytisine  0   *Alkaloids *Bridged Compounds *Quinolizines.  Eur J Med Chem 2001 Apr;36(4):375-88
paesslerin A  0   *Bridged Compounds *Sesquiterpenes.  Org Lett 2001 May 17;3(10):1415-7
6-acetoxycladiell-7(16),11-dien-3-ol  0   Diterpenes *Bridged Compounds *Furans.  J Am Chem Soc 2001 Sep 19;123(37):9033-44
furanocembranolide  0   *Bridged Compounds *Furans.  J Org Chem 2001 Nov 30;66(24):8037-41
longithorone A  0   *Bridged Compounds *Polycyclic Compounds.  J Am Chem Soc 2002 Feb 6;124(5):773-5
BisA compound  0   Telomerase/antagonists & inhibitors *Acridines *Bridged Compounds.  J Biomol Struct Dyn 2001 Dec;19(3):505-13
gaudichaudione A  0   *Bridged Compounds *Xanthenes.  Planta Med 2002 Mar;68(3):198-203
furanoheliangolide  0   *Bridged Compounds *Furans.  Chem Pharm Bull (Tokyo). 2004 Dec;52(12):1433-5
indisetron hydrochloride  0   *Bridged Compounds *Pyrazoles.  Gan To Kagaku Ryoho. 2005 Apr;32(4):567-73
cucurbit(8)uril  0   *Bridged Compounds *Imidazoles.  J Am Chem Soc. 2005 Oct 19;127(41):14511-7
quadricyclane  0   *Bridged Compounds *Polycyclic Compounds.  Angew Chem Int Ed Engl. 2005 May 20;44(21):3275-9
paulownin  13040-46-5   *Bridged Compounds *Lignans.  Z Naturforsch C 29(1/2):84;1974
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