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Luminescent Agents

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Definition: Compound such as LUMINESCENT PROTEINS that cause or emit light (PHYSICAL LUMINESCENCE).     
See Also Chromogenic Compounds; Fluorescent Dyes
Examples Fluorescent Dyes 		Other names Agents, Phosphorescent; Agents, Luminescent; Phosphorescent Agents
Substances having this pharmacologic action: isoluminol; 10,10'-dimethyl-9,9'-biacridinium; Luciferases, Renilla; Luciferases, Firefly; Green Fluorescent Proteins; Luciferases, Bacterial; Firefly Luciferin; Aequorin; Luciferases; Luminol; Europium; coelenterazine; red fluorescent protein; 2-methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo(1,2-alpha)pyrazin-3-one; 2-methyl-6-phenyl-3,7-dihydroimidazo(1,2-a)pyrazin-3-one
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
luciferase, Photinus  0   *Luciferases, Firefly Luminescent Agents.
luciferase, cypridina  0   *Luciferases Luminescent Agents.
LuxT protein, Vibrio harveyi  0   *Bacterial Proteins *DNA-Binding Proteins Luminescent Agents. Protein Expr Purif 2000 Oct;20(1):87-94
LuxS protein, Bacteria  EC 4.4.1.21   *Bacterial Proteins *Carbon-Sulfur Lyases Luminescent Agents. Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1639-44
LuxU protein, Vibrio  0   *Bacterial Proteins *Phosphoproteins Luminescent Agents. J Bacteriol 1999 Feb;181(3):899-906
dehydrocoelenterazine  0   *Imidazoles *Pyrazines Aequorin Luminescent Agents. Bioorg Med Chem Lett 1998 Oct 20;8(20):2919-24
6-(N-acetylphenylalanyl)aminoluciferin  0   *Firefly Luciferin Phenylalanine/*analogs & derivatives Luminescent Agents. Anal Biochem 1994 Sep;221(2):329-34
luxQ protein, Vibrio harveyi  EC 2.7.1.-   *Bacterial Proteins *Phosphotransferases *Transcription Factors Luminescent Agents. Mol Microbiol 1994 Jul;13(2):273-86
LuxP protein, Vibrio  0   *Bacterial Proteins Luminescent Agents. Mol Microbiol 1994 Jul;13(2):273-86
LuxO protein, Vibrio harveyi  0   *Bacterial Proteins *Repressor Proteins Luminescent Agents. Mol Microbiol 1994 May;12(3):403-12
spiropyran  0   *Benzopyrans *Indoles *Nitro Compounds Luminescent Agents. Biophys Biochem 1994 Apr;49(3):215-22
LuxI protein, Bacteria  0   *Bacterial Proteins *Transcription Factors Luminescent Measurements Luminescent Agents. J Bacteriol 1994 Jan;176(2):269-75
luxN protein, Vibrio harveyi  EC 2.7.1.-   *Protein Kinases *Bacterial Proteins *Transcription Factors Luminescent Agents. Mol Microbiol 1993 Aug;9(4):773-86
luxL protein, Vibrio harveyi  0   *Bacterial Proteins Luminescent Agents. Mol Microbiol 1993 Aug;9(4):773-86
luxM protein, Vibrio harveyi  0   *Bacterial Proteins Luminescent Agents. Mol Microbiol 1993 Aug;9(4):773-86
1-O-dodecanoylpanal  154381-71-2   *Tetrahydronaphthalenes Luminescent Agents. J Biolumin Chemilumin 1993 Jul-Aug;201-5
1-O-decanoylpanal  154381-70-1   *Tetrahydronaphthalenes Luminescent Agents. J Biolumin Chemilumin 1993 Jul-Aug;8(4):201-5
alkanol monooxygenase (FMN-linked)  EC 1.14.14.3   *Luciferases Luminescent Agents. Eur J Biochem 1991;201(1):161
luxD protein, Bacteria  EC 2.3.1.-   *Acyltransferases *Bacterial Proteins Luminescent Agents. Nucleic Acids Res 1990;18(18):5570
luxH protein, Vibrio harveyi  EC 5.4.99.-   *Bacterial Proteins *Intramolecular Transferases Luminescent Agents. J Biol Chem 1990;265(6):3513
luxG protein, Bacteria  EC 1.-   *Bacterial Proteins *Oxidoreductases Luminescent Agents. J Biol Chem 1990;265(6):3513
2-(6-hydroxyquinolyl)-2-thiazole-4-carboxylic acid  122364-83-4 4-Thiazolecarboxylic acid, 4,5-dihydro-2-(6-hydroxy-2-quinolinyl)-, (S)  *Hydroxyquinolines *Thiazoles Luminescent Agents. Photochem Photobiol 1989;49(5):689
22,23-dihydroavermectin B(1a)-4''-(4-((4-(ethyl(1,2,3,4-tetrahydro-1,4-dioxo-6-phthalazinyl)amino)butyl)amino)-4-oxobutanoate)  122047-12-5   Ivermectin/*analogs & derivatives Luminol/*analogs & derivatives Luminescent Agents. Anal Biochem 1989;177(2):291
LuxC protein, Bacteria  EC 1.2.1.50   *Bacterial Proteins *Oxidoreductases Luminescent Agents. Nucleic Acids Res 1988;16(4):1551
7,8-dihydropterin  17838-80-1 4(1H)-pteridinone, 2-amino-7,8-dihydro  *Pterins Luminescent Agents. Biochim Biophys Acta 1980;630(1):92
Renilla-luciferin sulfotransferase  EC 2.8.2.10   *Sulfotransferases Luminescent Agents Firefly Luciferin. Biochemistry 9(5):1184;1970
oxyluciferin  17297-78-8 Butanamide, N-(3-(3-((aminoiminomethyl)amino)propyl)-5-(1H-indol-3-yl)pyrazinyl)-2-methyl  *Indoles *Pyrazines Luminescent Agents. Biochemistry 16(11):2517;1977
sepharose-4B-(dodecanate)-5'-luciferinylglucuronate  80802-62-6 Agarose, 2-((11-carboxyundecyl)amino)-2-hydroxyethyl ether, 3-ester with 2-(4-carboxy-4,5-dihydro-2-thiazolyl)-6-benzothiazolyl D-glucuronate  *Benzothiazoles Sepharose/*analogs & derivatives Luminescent Agents Firefly Luciferin. Mech Ageing Dev 1981;17(3):275
2-amino-3-benzyl-5-(p-hydroxyphenyl)pyrazine  37156-84-6 Phenol, 4-(5-amino-6-(phenylmethyl)pyrazinyl)  *Pyrazines Aequorin Luminescent Agents. Biochemistry 11(9):1602;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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