encyclopedia of medical concepts
ψ 
ψ 

Phenylalanine

More information in Books or onNLM PubMed
Definition: An essential aromatic amino acid that is a precursor of MELANIN; DOPAMINE; noradrenalin (NOREPINEPHRINE), and THYROXINE.     
Examples Dihydroxyphenylalanine; Fenclonine; p-Fluorophenylalanine; Melphalan 		Other names Phenylalanine, L Isomer; L-Isomer Phenylalanine; Phenylalanine, L-Isomer; L-Phenylalanine; Endorphenyl
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
5,14-dioxo-12-(2-phenylalanine-N-ylethyl-1-yl)-1,2,3,5,5a,6,11,12,14,14a-decahydro-5H,14H-pyrolo(1,2-4,5)pyrazino(1,2-1,6)pyrido(3,4-b)indole  0   *Heterocyclic Compounds with 4 or More Rings Phenylalanine/*analogs & derivatives Urokinase-Type Plasminogen Activator/antagonists & inhibitors. ChemMedChem. 2011 Dec 9;6(12):2312-22.
N-undecyl-10-enoylphenylalanine  0   *Lipopeptides Phenylalanine/*analogs & derivatives. J Cosmet Dermatol. 2011 Sep;10(3):189-96.
2-amino-3-(2-(2-carboxyethyl)-5-chloro-4-nitrophenyl)propionic acid  0   Phenylalanine/*analogs & derivatives Receptors, AMPA/antagonists & inhibitors. J Med Chem. 2011 Oct 27;54(20):7289-98.
N-benzenesulfonyl-(S)-phenylalanine  0   Phenylalanine/*analogs & derivatives. Chirality. 2011 Apr;23(4):326-32
N-(p-toluenesulfonyl)-(S)-phenylalanine  0   Phenylalanine/*analogs & derivatives. Chirality. 2011 Apr;23(4):326-32
2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(3'-methoxybiphenyl-4-yl)ethoxy)-pyrimidin-4-yl)phenyl)propionic acid  0   *Biphenyl Compounds Phenylalanine/*analogs & derivatives Tryptophan Hydroxylase/antagonists & inhibitors. IDrugs 2010 Dec;13(12):921-8
4-(trifluoromethyl)phenylalanine  0   Phenylalanine/*analogs & derivatives. J Am Chem Soc 2007 Feb 7;129(5):1160-6
4-(2'-bromoisobutyroamido)phenylalanine  0   Phenylalanine/*analogs & derivatives. J Am Chem Soc 2010 Oct 6;132(39):13575-7
3-(4-iodophenyl)-2-(4-(3,4-dichlorophenyl)thiazol-2-ylamino)propionic acid  0   *Thiazoles Phenylalanine/*analogs & derivatives. Int J Antimicrob Agents 2010 Oct;36(4):364-8
2-amino-N-(2-(3,4-dihydroxyphenyl)ethyl)-3-phenylpropionamide  0   Dopamine/*analogs & derivatives Phenylalanine/*analogs & derivatives. J Liposome Res 2010 Sep;20(3):250-7
2-amino-N-(3-(biphenyl-4-yl)-1-(2-(5,6-dichloro-1H-benzimidazol-2-yl)pyrrolidin-1-yl)-1-oxobutan-2-yl)-2-methylpropanamide  0   *Benzimidazoles Phenylalanine/*analogs & derivatives. J Med Chem 2010 Oct 14;53(19):7251-63
N-(t-butyloxycarbonyl)-protected triphenylalanine  0   Phenylalanine/*analogs & derivatives. Small. 2010 Apr 23;6(8):945-51
9-(4-(1-(3-(2-amino-3-phenylpropionylamido)propyl)-1H-1,2,3-triazol-4-yl)butyrylamino)doxycycline  0   Doxycycline/*analogs & derivatives Phenylalanine/*analogs & derivatives. Chembiochem 2010 Mar 22;11(5):703-12
4-fluoro-1-(4-fluoro-(4-fluorophenyl)phenylalanyl)-2-pyrrolidinecarbonitrile  0   *Pyrrolidines Phenylalanine/*analogs & derivatives Dipeptidyl Peptidase 4. J Pharm Sci 2010 Jul;99(7):3030-40
poly (lactic acid-co-phenylalanine)  0   *Phenylalanine *Polymers *Lactic Acid. Guang Pu Xue Yu Guang Pu Fen Xi. 2009 Mar;29(3):661-4
N,N-dimethyl-phenylalanine  0   Phenylalanine/*analogs & derivatives. Anal Chim Acta. 2010 Mar 17;663(1):109-16
N,N-dimethyl-L-phenylalanine  0   Phenylalanine/*analogs & derivatives. Anal Chim Acta. 2010 Mar 17;663(1):109-6
4-propargyloxyphenylalanine  0   Phenylalanine/*analogs & derivatives. Bioconjug Chem 2010 Feb 17;21(2):255-63
CJ 672  0   *Amidines Phenylalanine/*analogs & derivatives. Xenobiotica 2010 Feb;40(2):
CJ 1737  0   *Amidines Phenylalanine/*analogs & derivatives. Xenobiotica 2010 Feb;40(2):93-101
3,5-dibromo-L-phenylalanine  0   Phenylalanine/*analogs & derivatives. Br J Pharmacol. 2009 Dec;158(8):2005-13
phenylalanine lauryl ester  0   *Laurates Phenylalanine/*analogs & derivatives. J Phys Chem B 2009 Oct 22;113(42):13959-70
methoxy polyethylene glycol-dihydroxyphenylalanine  0   *Polyethylene Glycols Phenylalanine/*analogs & derivatives. J Urol. 2009 Oct;182(4):1628-36
GS-9191  0   Phenylalanine/*analogs & derivatives. Antimicrob Agents Chemother. 2009 Jul;53(7):2777-84
trifluoromethyldiazirine-phenylalanine  0   Phenylalanine/*analogs & derivatives. Chem Commun (Camb). 2008 Nov 30;(44):5728-30
N-(N-((3-cyanophenyl)sulfonyl)-4-cyclobutylaminoprolyl)-4-((3',5'-dichloroisonicotinoyl)amino)phenylalanine  0   Niacinamide/*analogs & derivatives Phenylalanine/*analogs & derivatives. J Med Chem 2009 Jun 11;52(11):3499-52
2-nitrophenylalanine  0   Phenylalanine/*analogs & derivatives. Chem Biol. 2009 Feb 27;16(2):148-52
L-Phe-beta-napthylamide  0   Phenylalanine/*analogs & derivatives. Pharmazie. 2008 Dec;63(12):909-12
(benzoylphenyl)alanyl  0   Phenylalanine/*analogs & derivatives. Chemistry. 2009;15(1):67-70
4'-(N-((4'-phenyl)phenethyl)carboxamido)phenylalanine  0   Phenylalanine/*analogs & derivatives. Chem Biol Drug Des 2008 Nov;72(5):337-40
N-6-(4-(benzyloxy)phenyl)pyrimidin-4-ylphenylalanine  0   *Pyrimidines Phenylalanine/*analogs & derivatives Receptors, Epoprostenol/antagonists & inhibitors. Eur J Pharmacol 2008 Aug 20;590(1-3):322-6
2-fluoromethylphenylalanine  0   Phenylalanine/*analogs & derivatives Fluorine Radioisotopes. Nucl Med Biol 2008 May;35(4):425-32
N-undecanoylphenylalanine  0   Phenylalanine/*analogs & derivatives. J Fluoresc 2008 Mar;18(2):285-96
N-(1-(3,5-dichlorobenzenesulfonyl)-2S-methyl-azetidine-2-carbonyl)-L-4-(2',6'-dimethoxyphenyl)phenylalanine  0   Phenylalanine/*analogs & derivatives. Xenobiotica 2008 Feb;38(2):223-37
1-(methylaminocarbonyl)-3-phenylpropanaminium  0   Phenylalanine/*analogs & derivatives. Acta Crystallogr C 2008 Jan;64(Pt 1):o10-4
N'-octadecyl-N(alpha)-(4-vinyl)-benzoyl-L-phenylalanineamide  0   Phenylalanine/*analogs & derivatives. Chemistry 2008;14(4):1312-21
fluorenylmethoxycarbonyl-4-(1-chloroethyl)phenylalanine  0   *Fluorenes Phenylalanine/*analogs & derivatives. J Am Chem Soc 2008 Jan 23;130(3):1041-7
N-(6-hydroxyindol-3-ylacetyl)-phenylalanine  0   *Indoleacetic Acids Phenylalanine/*analogs & derivatives. Phytochemistry 2007 Jun;68(12):1651-63
5'-O-(N-(phenylalanyl)sulfamoyl)adenosine  0   Adenosine/*analogs & derivatives Phenylalanine/*analogs & derivatives. Nucleic Acids Symp Ser (Oxf) 2005;(49):265-6
2,8,14,20-tetrakis(L-valinamido)(4)resorcinarene  0   Phenylalanine/*analogs & derivatives Valine/*analogs & derivatives. Angew Chem Int Ed Engl. 2006 Apr 21;45(17):2717-20
N-formylphenylalanine trifluoroethyl ester  0   Phenylalanine/*analogs & derivatives. Biochemistry 2007 Apr 3;46(13):4037-44
p-tert-butylcalix(6)arene p-bromophenylalanine, potassium salt  0   *Calixarenes Phenylalanine/*analogs & derivatives. Chem Commun (Camb) 2006 Sep 14;(34):3606-8
diphenylalanine  0   Phenylalanine/*analogs & derivatives. Chem Commun (Camb). 2006 Jun 14;(22):2332-4
3,5-difluoro-4-azidophenylalanine  0   *Azides Phenylalanine/*analogs & derivatives. J Recept Signal Transduct Res 2006;26(5-6):435-51
dl-phenylalanine dl-phenylalaninium picrate  0   *Picrates Phenylalanine/*analogs & derivatives. Spectrochim Acta A Mol Biomol Spectrosc. 2006 Oct;65(2):414-20
N-(2-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)propionyl)phenylalanine  0   Cytosine/*analogs & derivatives Phenylalanine/*analogs & derivatives. Acta Crystallogr C 2005 Oct;61(Pt 10):o577-82
UA 0713  0   *Triterpenes Phenylalanine/*analogs & derivatives Protein Tyrosine Phosphatases/antagonists & inhibitors. Biochim Biophys Acta 2006 Oct;1760(10):1505-12
N,N-diphenylalanyl protoporphyrin  0   *Porphyrins Phenylalanine/*analogs & derivatives. Photochem Photobiol 2004 Nov-Dec;80(3):486-91
phenylalanyllactose  0   *Glucosides Phenylalanine/*analogs & derivatives. Int J Biol Macromol 2006 Mar 30;38(2):89-93
phenylalanylglucose  0   *Glucosides Phenylalanine/*analogs & derivatives. Int J Biol Macromol 2006 Mar 30;38(2):89-93
chromium (D-Phenylalanine)3  0   *Organometallic Compounds Phenylalanine/*analogs & derivatives. J Inorg Biochem. 2006 Jul;100(7):1187-93
beta-(4-borono-2,6-difluorophenyl)alaninol  0   *Boronic Acids Phenylalanine/*analogs & derivatives. Bioorg Med Chem 2006 May 15;14(10):3258-62
beta-(4-borono-2,6-difluorophenyl)alanine  0   *Boronic Acids Phenylalanine/*analogs & derivatives. Bioorg Med Chem 2006 May 15;14(10):3258-62
3-amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-(1,2,4)triazolo(1,5-a)pyridin-6-ylphenyl)butanamide  0   *Triazoles Phenylalanine/*analogs & derivatives.
Pharma Action Dipeptidyl-Peptidase IV Inhibitors 		J Med Chem 2006 Jun 15;49(12):3614-27
N-tosyl-(S)-phenylalanine  0   *Tosyl Compounds Phenylalanine/*analogs & derivatives. Org Biomol Chem. 2005 Jan 21;3(2):360-5
2-tert-butoxycarbonylamino-3-(4-(2-(2-hydroxyethyl)-5-methoxy-3-oxo-2,3-dihydropyridazin-4-yl)phenyl)propionic acid 2-hydroxyethyl ester  0   *Pyridazines Phenylalanine/*analogs & derivatives. J Med Chem 2006 Jun 1;49(11):3402-11
PGE 6292544  0   *Sulfonamides Phenylalanine/*analogs & derivatives. Inflamm Res 2006 Feb;55(2):60-5
N-((9-fluorenyl)methoxycarbonyl)-4-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenylalanine  0   Diazomethane/*analogs & derivatives Phenylalanine/*analogs & derivatives. J Med Chem 2006 Apr 6;49(7):2200-9
poly(gamma-glutamic acid)-graft-phenylalanine ethylester copolymer  0   *Polyglutamic Acid Phenylalanine/*analogs & derivatives. Biomacromolecules 2006 Jan;7(1):297-303
N-(2-(mercaptomethyl)-3-methylbutanoyl)-4-(1H-pyrazol-1-yl)phenylalanine  0   *Pyrazoles Phenylalanine/*analogs & derivatives Peptidyl-Dipeptidase A/antagonists & inhibitors Neprilysin/antagonists & inhibitors. J Pharmacol Exp Ther 2005 Dec;315(3):1306-13
more...

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy