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Benzylisoquinolines

More information in Books or onNLM PubMed
Definition: ISOQUINOLINES with a benzyl substituent.     
Examples Aporphines; Berberine Alkaloids; Bicuculline; Papaverine; Toxiferine; Tubocurarine 		Other names Bis Benzylisoquinolines; Bis Benzyl Isoquinolines; Benzyl Isoquinolines; Bis-Benzylisoquinolines; Bis-Benzyl-Isoquinolines; Benzyl-Isoquinolines; Bisbenzylisoquinolines
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
O-methylarmepavine  0   *Benzylisoquinolines. Fitoterapia. 2011 Jun;82(4):666-75
tabienine B  0   *Benzylisoquinolines Alkaloids. Nat Prod Res. 2011 May;25(9):934-8
H1 (tetrandrine derivative)  0   *Benzylisoquinolines Drug Resistance, Neoplasm/drug effects. Cancer Chemother Pharmacol. 2011 May;67(5):1017-25
wattisine B  0   *Benzylisoquinolines. Chem Pharm Bull (Tokyo). 2010;58(7):986-8
wattisine A  0   *Benzylisoquinolines. Chem Pharm Bull (Tokyo). 2010;58(7):986-8
4-chlorobenzoylberbamine  0   *Benzylisoquinolines. Oncol Rep 2010 Mar;23(3):709-16
1-(4-hydroxybenzyl)-6,7-methylenedioxy-2-methylisoquinolinium trifluoroacetate  0   *Benzylisoquinolines. J Nat Prod. 2009 Aug;72(8):1541-3
pseudocoptisine  0   *Benzylisoquinolines. Biol Pharm Bull 2008 Jan;31(1):159-62
bromotetrandrine  0   *Benzylisoquinolines Alkaloids. Yao Xue Xue Bao 2005 May;40(5):453-6
latifolian B  0   *Benzylisoquinolines. J Nat Prod 2005 Jul;68(7):1080-2
latifolian A  0   *Benzylisoquinolines. J Nat Prod 2005 Jul;68(7):1080-2
coccuorbiculatine A  0   *Benzylisoquinolines. J Nat Prod 2005 Jul;68(7):1056-60
10-hydroxyisotrilobine  0   *Benzylisoquinolines. J Nat Prod 2005 Jul;68(7):1056-60
E6 isoquinoline  0   *Benzylisoquinolines. Acta Pharmacol Sin. 2003 Nov;24(11):1143-9
3,4-methylenedeoxy-2,8,9-trimethoxypavinan  142735-70-4   *Benzylisoquinolines Alkaloids. Antivir Chem Chemother 2003 Mar;14(2):75-80
O-methylneocaryachine  0   *Benzylisoquinolines. Br J Pharmacol 2002 Jun;136(3):459-71
O,O-acetyldaurisoline  0   *Benzylisoquinolines. Yao Xue Xue Bao 1998;33(4):241-4
bisbenzylisoquinoline  0   *Benzylisoquinolines. Zhongguo Zhong Yao Za Zhi 1998 Jul;23(7); 427-8, inside back cover
isopavine N-oxide A  0   *Oxides *Benzylisoquinolines. Fitoterapia 2001 Feb;72(2):120-3
N-methylberbamine  0   *Benzylisoquinolines Potassium Channels. Chung Kuo Yao Li Hseuh Pao 1998 Jan;19(1):24-6
2,3,8-trimethoxy-7-hydroxyisopavine  0   *Benzylisoquinolines. Phytochemistry 1998 May;48(2):403-5
berbamunine  0   *Benzylisoquinolines. Gene 1996 Nov 7;179(1):73-81
caryachine  37687-27-7   *Dioxoles *Benzylisoquinolines Plant Extracts. Br J Pharmacol 1995 Dec;116(8):3211
O,O-bisacetyldaurisoline  132139-17-4   *Benzylisoquinolines. Chung Kuo Yao Li Hsueh Pao 1991 Nov;12(6):494-6
7-O-isopropyl fangchinoline  125247-70-3   *Benzylisoquinolines. Gen Pharmacol 1991;22(1):165
7-O-ethyl fangchinoline  118160-59-1   *Benzylisoquinolines. Gen Pharmacol 1991;22(1):165
hernandezine  6681-13-6   *Benzylisoquinolines Drugs, Chinese Herbal. Yao Hsueh Hsueh Pao 1990;25(5):330
armepavine  3423-14-1   *Benzylisoquinolines. J Nat Prod 1990;53(2):533
7-O-demethylisothalicberine  73711-14-5   *Benzylisoquinolines Berberis. Gen Pharmacol 1989;20(5):621
fangchinoline  33889-68-8   *Benzylisoquinolines Drugs, Chinese Herbal. Chung Yao Tung Pao 1988;13(12):36
antioquine  93767-27-2   *Benzylisoquinolines. Arch Int Pharmacodyn 1989;297:205
neferine  2292-16-2   *Benzylisoquinolines Drugs, Chinese Herbal. Yao Hsueh Hsueh Pao 1988;23(4):241
thalidasine  16623-56-6 6,6',7,7',12-Pentamethoxy-2,2'-dimethyl-thalidasan  *Benzylisoquinolines. Yao Hsueh Hsueh Pao 1988;23(3):196
O-(4-ethoxybutyl)berbamine  106006-09-1 Berbaman, 12-(4-ethoxybutoxy)-6,6',7-trimethoxy-2,2'-dimethyl  *Benzylisoquinolines. Biochem Biophys Res Commun 1986;140(1):461
dauricine  524-17-4   *Tetrahydroisoquinolines *Benzylisoquinolines.
Pharma Action Anti-Arrhythmia Agents ; Anti-Inflammatory Agents, Non-Steroidal ; Antihypertensive Agents ; Calcium Channel Blockers ; Platelet Aggregation Inhibitors 		Chung Kuo Yao Hsueh Pao 1982;3(3):178
berbamine  478-61-5   *Benzylisoquinolines.
Pharma Action Anti-Arrhythmia Agents ; Anti-Inflammatory Agents, Non-Steroidal ; Antihypertensive Agents ; Calcium Channel Blockers 		Yao Hsueh Hsueh Pao 1980;15(4):248
daurisoline  70553-76-3 (R-(R*,R*))-1,2,3,4-tetrahydro-1-((4-hydroxy-3-(4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)phenoxy)phenyl)methyl)-6-methoxy-2-methyl-7-iso quinolinol  *Benzylisoquinolines. Yao Hsueh Hsueh Pao 14(7):439;1979
N-(2)-nor-d-tetrandrine  38769-08-3   *Benzylisoquinolines. Lloydia 40(3):239;1977
hydrastine  118-08-1 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinoline-5-yl)-1(3H)-isobenzo furan  *Benzylisoquinolines Hydrastis. J Am Chem Soc 98(21):6714;1976; J Chem Soc (Perkin) 4:374;1977; Neirofiziologiia 10(3):295;1978
tetrandrine  518-34-3   *Benzylisoquinolines Drugs, Chinese Herbal.
Pharma Action Antimalarials ; Antineoplastic Agents, Phytogenic ; Antiviral Agents ; Calcium Channel Blockers ; Immunosuppressive Agents 		Biochem Pharmacol 25(16):1887;1976; Cancer Chemother Rep (Part 3) 5(1):79;1974; Chin Med J (Engl) 2(2):97;1976; Chin Med J (Engl) 92(3):193;1979; J Am Chem Soc 98(7):1947;1976; J Org Chem 41(15):2548;1976
cepharanthine  481-49-2   *Benzylisoquinolines.
Pharma Action Anti-Inflammatory Agents, Non-Steroidal ; Antineoplastic Agents, Phytogenic ; Radiation-Protective Agents 		Acta Med Jpn 47(1):1;1977; Nippon Acta Radiol 37(12):1156;1977; Nippon Yakurigaku Zasshi 1979;75(3):207
reticuline  485-19-8   *Benzylisoquinolines. FEBS Lett 49(3):396;1975; J Am Chem Soc 98(7):1956;1976; J Chem Soc (Perkin I) 14:1662;1977; J Pharm Sci 60(11):1672;1971

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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