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Potassium Channels

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Definition: Cell membrane glycoproteins that are selectively permeable to potassium ions. At least eight major groups of K channels exist and they are made up of dozens of different subunits.  DF: K CHANNELS   
See Also Sodium-Potassium-Exchanging ATPase
Examples Potassium Channels, Calcium-Activated; Potassium Channels, Inwardly Rectifying; Potassium Channels, Tandem Pore Domain; Potassium Channels, Voltage-Gated 		Other names Ion Channels, Potassium; Potassium Ion Channel; Channels, Potassium Ion; Channels, Potassium; Channel, Potassium Ion; Channel, Potassium; Potassium Ion Channels; Potassium Channel; Ion Channel, Potassium
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
KCTD7 protein, mouse  0   *Potassium Channels. Mol Neurobiol. 2011 Aug;44(1):111-21
quiver protein, Drosophila  0   *Potassium Channels *Drosophila Proteins. J Neurogenet 2010 Jul;24(2):67-74
Elk protein, Drosophila  0   *Potassium Channels *Drosophila Proteins. Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 Sep 1;66(Pt 9):1056-9
KCTD15 protein, human  0   *Potassium Channels. Obesity (Silver Spring). 2010 Jun;18(6):1212-7
TRESK protein, rat  0   *Potassium Channels. Neurosci Lett. 2009 Nov 6;465(1):79-84
KCTD7 protein, human  0   *Potassium Channels. Ann Neurol 2007 Jun;61(6):579-86
4-methyl-N-(2,2,2-trichloro-1-(3-pyridin-3-ylthioureido)ethyl)benzamide  0   *Benzamides *Pyridines Potassium Channels. Br J Pharmacol. 2007 Jun;151(4):467-75
KCTD5 protein, human  0   *Potassium Channels. Virology 2007 May 25;362(1):192-206
NALCN protein, mouse  0   *Ion Channels *Nerve Tissue Proteins Calcium Channels Potassium Channels. Cell 2007 Apr 20;129(2):371-83
Slick protein, mouse  0   *Potassium Channels. J Neurosci 2007 Mar 7;27(10):2617-27
KchA protein, Helicobacter pylori  0   *Potassium Channels. EMBO J 2007 Jan 10;26(1):232-41
HCN4 protein, rat  0   *Potassium Channels. Brain Res Mol Brain Res 2000 Sep 30;81(1-2):129-39
HCN3 protein, rat  0   *Potassium Channels. Brain Res Mol Brain Res 2000 Sep 30;81(1-2):129-39
TASK3 protein, mouse  0   *Potassium Channels. Neuron 2006 Jun 1;50(5):711-22
DPP6 protein, human  EC 3.4.-   *Dipeptidyl-Peptidases and Tripeptidyl-Peptidases *Nerve Tissue Proteins *Potassium Channels. J Physiol. 2005 Jun 15;565(Pt 3):751-6
Kcnk4 protein, rat  0   *Potassium Channels.
Kcnk4 protein, mouse  0   *Potassium Channels.
KCNK4 protein, human  0   *Potassium Channels.
Kctd10 protein, rat  0   *Potassium Channels. Biochim Biophys Acta. 2005 Jul 10;1729(3):200-3
BKCa protein, rat  0   *Potassium Channels. FEBS Lett 2004 Jul 16;570(1-3):143-8
KCTD11 protein, human  0   *Potassium Channels. Proc Natl Acad Sci U S A 2004 Jul 20;101(29):10833-8
Erg3 protein, mouse  0   *Potassium Channels. Gene Expr Patterns 2003 Dec;3(6):767-76
TRESK-2 protein, mouse  0   *Potassium Channels. J Biol Chem 2004 Jul 2;279(27):28063-70
Trik protein, mouse  0   *Potassium Channels. J Biol Chem. 2004 Apr 30;279(18):18550-8
KCNT2 protein, human  0   *Potassium Channels. J Neurosci 2003 Dec 17;23(37):11681-91
slick protein, rat  0   *Potassium Channels. J Neurosci 2003 Dec 17;23(37):11681-91
Slo2 protein, mouse  0   *Potassium Channels. Biochem Biophys Res Commun 2003 Oct 31;310(4);1140-7
Sup-9 protein, C elegans  0   *Potassium Channels *Caenorhabditis elegans Proteins. J Neurosci 2003 Oct 8;23(27):9133-45
YMUC potassium channel protein, S cerevisiae  0   *Potassium Channels *Saccharomyces cerevisiae Proteins. J Bioenerg Biomembr 2002 Aug;34(4);299-306
KCNK18 protein, human  0   *Potassium Channels. J Biol Chem 2003 Jul 25;278(30):27406-12
UNC-103 protein, C elegans  NM_065423   *Potassium Channels *Caenorhabditis elegans Proteins. J Neurosci 2003 Apr 1;23(7):2696-705
MPS-1 protein, C elegans  0   *Potassium Channels *Caenorhabditis elegans Proteins. J Biol Chem 2003 Apr 4;278(14):12415-24
KCNRG protein, human  0   *Potassium Channels. FEBS Lett 2003 Mar 27;539(1-3):156-60
DPPX protein, rat  0   *Nerve Tissue Proteins *Potassium Channels. Neuron 2003 Feb 6;37(3):449-61
HCN3 protein, human  0   *Potassium Channels *Cyclic Nucleotide-Gated Cation Channels. J Neurosci 2003 Feb 15;23(4):1169-78
kefA2 protein, E coli  0   *Potassium Channels *Escherichia coli Proteins. Mol Microbiol 2002 Jan;43(2):521-36
KC 0912  0   *Benzopyrans *Piperidines Potassium Channels. Naumyn Schmiederbergs Arch Pharmacol 2002 Mar;365(3):220-30
parabutoxin 3 protein, Parabuthus transvaalicus  0   *Scorpion Venoms Potassium Channels/antagonists & inhibitors. Eur J Biochem 2002 Apr;269(7):1854-65
TrkH protein, E coli  0   *Potassium Channels *ATP-Binding Cassette Transporters *Escherichia coli Proteins. J Bacteriol 1995 Apr;177(7):1908-10
VFK1 protein, Vicia faba  0   *Plant Proteins *Potassium Channels. Plant J 2001 Sep;27(6):571-80
3-butyl-5-(4-(((2,2-dimethylcyclopent-1-yl)methyl)aminocarbonyl)phenyl)-1,2,4-oxadiazole  0   *Oxadiazoles Potassium Channels/antagonists & inhibitors. J Med Chem 2001 Nov 8;44(23):3764-7
1-((9-benzyl)fluoren-9-yl)-4-(hexahydro-1H-azepin-1-yl)but-2-yne  0   *Azepines *Fluorenes Potassium Channels/antagonists & inhibitors. J Med Chem 2001 Sep 27;44(20):3244-53
AKT3 protein, Arabidopsis  0   *Potassium Channels *Arabidopsis Proteins. J Exp Bot 2001 Jan;52(354):181-2
tamulustoxin protein, Mesobuthus tamulus  0   *Scorpion Venoms Potassium Channels/antagonists & inhibitors. Arch Biochem Biophys 2001 Jan 1;385(1):138-44
TWK-18 protein, C elegans  0   *Potassium Channels *Caenorhabditis elegans Proteins. J Neurosci 2000 Oct 15;20(20):7517-24
9-methoxy-2,2,6-trimethyl-2,6-dihydro-5H-pyrrano(3,2-c)quinolin-5-one  0   *Quinolones Potassium Channels/antagonists & inhibitors. J Med Chem 2001 Apr 12;44(8):1249-56
8-methoxy-2-(1'-methylethyl)-5-methyl-4,5-dihydrofuro(3,2-c)quinolin-4-one  0   *Furans *Quinolones Potassium Channels/antagonists & inhibitors. J Med Chem 2001 Apr 12;44(8):1249-56
BIIA388CL  0   *Isoquinolines Potassium Channels. Neuropharmacology 2001;40(2):233-41
KDC1 protein, Daucus carota  0   *Plant Proteins *Potassium Channels. J Biol Chem 2000 Dec 15;275(50):39420-6
ZMK2 protein, Zea mays  0   *Plant Proteins *Potassium Channels. Plant J 2000 Oct;24(2):139-45
ZMK1 protein, Zea mays  0   *Plant Proteins *Potassium Channels. Plant J 2000 Oct;24(2):139-45
7-chloro-3-isopropylamino-4H-1,2,4-benzothiadiazine 1,1-dioxide  0   Diazoxide/*analogs & derivatives Potassium Channels/agonists. Diabetologia 2000 Jun;43(6):723-32
KC 515  0   *Benzopyrans Potassium Channels/agonists. Bioorg Med Chem 2000 Jun;8(6):1393-405
UCL 1848  0   *Quinolinium Compounds Potassium Channels/antagonists & inhibitors. J Med Chem 2000 Sep 21;43(19):3478-81
BmP02 peptide  0   *Peptides *Scorpion Venoms Potassium Channels/antagonists & inhibitors. Regul Pept 2000 Jun 30;90(1-3):85-92
BmP03 peptide  0   *Peptides *Scorpion Venoms Potassium Channels/antagonists & inhibitors. Regul Pept 2000 Jun 30;90(1-3):85-92
NNC 55-0118  0   Diazoxide/*analogs & derivatives Potassium Channels/agonists. Diabetes 2000 Jul;49(7):1131-6
WAY 151616  0   *Benzylamines *Cyclobutanes Potassium Channels/agonists. J Med Chem 2000 Mar 23;43(6):1203-14
4-(3,4-dioxo-2-(1,2,2-trimethylpropylamino)cyclobut-1-enylamino)-3-ethylbenzonitrile  0   *Cyclobutanes *Nitriles Potassium Channels/agonists. J Med Chem 2000 Mar 23;43(6):1187-202
Kcv potassium channel, Chlorella virus  0   *Viral Proteins *Potassium Channels. Science 2000 Mar 3;287(5458):1641-4
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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