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Drug Resistance, Neoplasm

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Definition: Resistance or diminished response of a neoplasm to an antineoplastic agent in humans, animals, or cell or tissue cultures.  DF: DRUG RESISTANCE NEOPL    Other names Resistance, Antineoplastic Drug; Resistance, Antineoplastic Agent; Neoplasm Drug Resistance; Antineoplastic Agent Resistance; Drug Resistance, Antineoplastic; Antineoplastic Drug Resistance; Antibiotic Resistance, Neoplasm
 
SubstanceCAS Registry & nameCategoriesSource
H1 (tetrandrine derivative)  0   *Benzylisoquinolines Drug Resistance, Neoplasm/drug effects. Cancer Chemother Pharmacol. 2011 May;67(5):1017-25
2-(N-(4-methoxyphenylethylaminocarbonyl))-5-hydroxychromone  0   *Chromones Drug Resistance, Multiple Drug Resistance, Neoplasm. J Med Chem 2005 Nov 17;48(23):7275-81
2-(N-(3,4-dimethoxyphenylethylaminocarbonyl))-5-hydroxychromone  0   *Chromones Drug Resistance, Multiple Drug Resistance, Neoplasm. J Med Chem 2005 Nov 17;48(23):7275-81
2-(4-n-butylpiperazin-1-ylcarbonyl)-5-hydroxychromone  0   *Chromones *Piperazines Drug Resistance, Multiple Drug Resistance, Neoplasm. J Med Chem 2005 Nov 17;48(23):7275-81
9-hydroxy-2-(2-(dimethylamino)ethyl)-6-((2-(dimethylamino)ethyl)amino)-2,3-dihydro-1H,7H-pyrimido(5,6,1-de)acridine-1,3,7-trione  0   *Acridines *Pyrimidinones Drug Resistance, Multiple Drug Resistance, Neoplasm. J Med Chem 1999 Jul 15;42(14):2535-41
9-amino-2-(2-(dimethylamino)ethyl)-6-((2-(dimethylamino)ethyl)amino)-2,3-dihydro-1H,7H-pyrimido(5,6,1-de)acridine-1,3,7-trione  0   *Acridines *Pyrimidinones Drug Resistance, Multiple Drug Resistance, Neoplasm. J Med Chem 1999 Jul 15;42(14):2535-41
6-((2-aminoethyl)amino)-2-(2-(dimethylamino)ethyl)-2,3-dihydro-1H,7H-pyrimido(5,6,1-de)acridine-1,3,7-trione  0   *Acridines *Pyrimidinones Drug Resistance, Multiple Drug Resistance, Neoplasm. J Med Chem 1999 Jul 15;42(14):2535-41
MM 36  0   *Anisoles *Nitriles Drug Resistance, Multiple Drug Resistance, Neoplasm. J Med Chem 1999 May 20;42(10):1687-97
NfsA protein, E coli  EC 1.7.-   *Nitroreductases *Escherichia coli Proteins Flavoproteins Drug Resistance, Neoplasm. J Bacteriol 1998 Nov;180(21):5529-39
MdaB protein, E coli  0   *Drug Resistance, Neoplasm *Escherichia coli Proteins. Proc Natl Acad Sci U S A 1995 Sep 12;92(19):8950-4

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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