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Mefruside

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Definition: A benzene-sulfonamide-furan. It is used as a diuretic that affects the concentrating ability of the KIDNEY, increases SODIUM CHLORIDE excretion, but may not spare POTASSIUM. It inhibits CARBONIC ANHYDRASES and may increase the blood URIC ACID level.     
Pharmacological Action Diuretics
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
mefruside lactone  14599-36-1 1,3-benzenedisulfonamide, 4-chloro-N(1)-methyl-N(1)-((tetrahydro-2-methyl-5-oxo-2-furanyl)methyl)  Mefruside/*analogs & derivatives. J Chromatogr 1980;182(2):179
mefrusid, methyldopa, reserpine drug combination  0   *Mefruside *Methyldopa *Reserpine Drug Combinations. Med Monatschr 27(9):418;1973
inositol nicotinate, mefruside, reserpine drug combination  0   *Mefruside *Nicotinic Acids *Reserpine Drug Combinations.
Pharma Action Antihypertensive Agents 		Med Klin 70(3):102;1975; Med Welt 37:1617;1970

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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