encyclopedia of medical concepts
ψ
Fenclonine
More information
in Books
or on
Definition
: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
Pharmacological Action
Enzyme Inhibitors
;
Serotonin Antagonists
Other names
para-
Chlorophenylalanine; p-
Chlorophenylalanine; para Chlorophenylalanine; Hydrochloride, Fenclonine; Hydrobromide, Fenclonine; Fenclonine, (D)-
Isomer; Fenclonine Hydrochloride; Fenclonine Hydrobromide; Fenclonine (L)-
Isomer; Fenclonin; DL-
3-
(4-
Chlorophenyl)alanine; CP-
10,188
Substance
CAS Registry & name
Categories
Source
Drugs
*
4-
chlorophenylalanine ethyl ester
38964-54-4
Fenclonine/*analogs & derivatives.
J Dent Res 1981;60(2):182
4-
chlorophenylalanine methyl ester
23434-96-0
Fenclonine/*analogs & derivatives.
J Neurochem 32(6):1613;1979