Definition: A subtype of non-receptor protein tyrosine phosphatases that includes two distinctive targeting motifs; an N-terminal motif specific for the INSULIN RECEPTOR, and a C-terminal motif specific for the SH3 domain containing proteins. This subtype includes a hydrophobic domain which localizes it to the ENDOPLASMIC RETICULUM.
Other names Protein Tyrosine Phosphatase, Non Receptor Type 1; Protein Tyrosine Phosphatase HA2; Protein-Tyrosine Phosphatase HA2; Protein Tyrosine Phosphatase 1B; PTPase HA2; PTPase 1B