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HIV Fusion Inhibitors

More information in Books or onNLM PubMed
Definition: Inhibitors of the fusion of HIV to host cells, preventing viral entry. This includes compounds that block attachment of HIV ENVELOPE PROTEIN GP120 to CD4 RECEPTORS.     
See Also Membrane Fusion 		Other names Entry Inhibitors, HIV; HIV Cell Fusion Inhibitors; HIV Entry Inhibitors; Fusion Inhibitors, HIV
Substances having this pharmacologic action: enfuvirtide
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Qadirvirtide  0   *Peptides HIV Fusion Inhibitors. Pak J Pharm Sci. 2011 Oct;24(4):593-5
BMS-488043  0   *Piperazines HIV Fusion Inhibitors. J Virol 2006 Apr;80(8):4017-25
TAK-220  0   *Piperidines HIV Fusion Inhibitors. Antimicrob Agents Chemother. 2005 Nov;49(11):4708-15
maraviroc  0   *Cyclohexanes *Triazoles Receptors, CCR5/antagonists & inhibitors HIV Fusion Inhibitors. Drug Metab Dispos. 2005 Apr;33(4):587-95SELZENTRY
873140 compound  0   *Benzoates *Piperazines *Spiro Compounds HIV Fusion Inhibitors. Mol Pharmacol 2005 Apr;67(4):1268-82
TNX-355  0   *Antibodies, Monoclonal HIV Fusion Inhibitors. AIDS Patient Care STDS. 2003 Dec;17(12):655
BMS-378806  0   *Piperazines HIV Fusion Inhibitors. J Virol 2003 Oct;77(19):10528-36
PRO-140 monclonal antibody  0   *HIV Antibodies *Antibodies, Monoclonal, Humanized Anti-HIV Agents Receptors, CCR5 HIV Fusion Inhibitors. Aids Patient Care STDS 2000 Dec;14(12):671; IDrugs. 2001 Sep;4(9):1068-71
TAK 779  229005-80-5   *Amides *Quaternary Ammonium Compounds Receptors, CCR5/antagonists & inhibitors HIV Fusion Inhibitors. Proc Natl Acad Sci U S A 1999 May 11;96(10):5698-703
CD4-IgG(2)  0   *CD4 Immunoadhesins HIV-1 HIV Fusion Inhibitors. AIDS Res Hum Retroviruses 1995 May;11(5):533-9
JM 3100  155148-31-5   *Heterocyclic Compounds Receptors, CXCR4/antagonists & inhibitors HIV Fusion Inhibitors.
Pharma Action Anti-HIV Agents 		Antimicrob Agents Chemother 1994 Apr;38(4):668-74MOZOBIL

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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