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Interleukin-6

More information in Books or onNLM PubMed
Definition: A cytokine that stimulates the growth and differentiation of B-LYMPHOCYTES and is also a growth factor for HYBRIDOMAS and plasmacytomas. It is produced by many different cells including T-LYMPHOCYTES; MONOCYTES; and FIBROBLASTS.  DF: IL 6 or IL6   
See Also Hybridomas; Plasmacytoma 		Other names Plasmacytoma Growth Factor; Myeloid Differentiation-Inducing Protein; MGI-2; IL-6; Hybridoma Growth Factor; Hepatocyte-Stimulating Factor; Myeloid Differentiation Inducing Protein; Interleukin 6; Hepatocyte Stimulating Factor; Growth Factor, Plasmacytoma; Growth Factor, Hybridoma; Differentiation-Inducing Protein, Myeloid; Differentiation Factor, B Cell; Differentiation Factor 2, B Cell; B Cell Stimulatory Factor 2; B Cell Differentiation Factor 2; B Cell Differentiation Factor; IFN-beta 2; Differentiation Factor-2, B-Cell; Differentiation Factor, B-Cell
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
duanbanhuain B  0   *Peptides, Cyclic Interleukin-6/antagonists & inhibitors Collagen Type IV/antagonists & inhibitors. Bioorg Med Chem Lett. Dec 15;21(24):7434-9.
duanbanhuain A  0   *Peptides, Cyclic Interleukin-6/antagonists & inhibitors Collagen Type IV/antagonists & inhibitors. Bioorg Med Chem Lett. Dec 15;21(24):7434-9.
quercetin 3-O-(2''-galloyl)glucopyranoside  0   *Glucosides Quercetin/*analogs & derivatives Interleukin-6/antagonists & inhibitors. Cytokine 2007 Sep;39(3):207-15
IL6 protein, human  0   *Interleukin-6.
neuropoietin, mouse  0   *Interleukin-6. Proc Natl Acad Sci U S A 2004 Apr 6;101(14)4827-32
SANT-7  0   Interleukin-6/*analogs & derivatives. Int J Cancer 2001 Sep 1;93(5):674-80
TJU 103  0   *Organic Chemicals Interferon-gamma/antagonists & inhibitors Interleukin-1/antagonists & inhibitors Tumor Necrosis Factor-alpha/antagonists & inhibitors Interleukin-6/antagonists & inhibitors. Antimicrob Agents Chemother 2000 Apr;44(4):1067-9
interleukin-6, RRV-HHV-8  0   *Viral Proteins *Interleukin-6. J Virol 1999 Jul;73(7):6177-81
2-amino-4-(4-chlorophenyl)-5-methylthiazole  0   *Thiazoles Interleukin-6/antagonists & inhibitors. Bioorg Med Chem Lett 1999 Apr 5;9(7):957-60
interleukin 6-interleukin 6 receptor fusion protein, recombinant  0   *Recombinant Fusion Proteins *Interleukin-6 *Receptors, Interleukin-6. Nat Biotechnol 1997 Feb;15(2):142-5
22-interleukin-6 cysteine(3,4)  0   *Interleukin-6. J Chromatogr A 1995 Aug 11;709(1):135-46
CGP 47969A  0   *Piperazines Interleukin-1/antagonists & inhibitors Cytokines/antagonists & inhibitors Tumor Necrosis Factor-alpha/antagonists & inhibitors Interleukin-6/antagonists & inhibitors. J Rheumatol 1994 Nov;21(11):1992-7
recombinant fusion protein IL-6 - IL-2  0   *Interleukin-2 *Interleukin-6 Recombinant Fusion Proteins. Stem Cells (Dayt) 1994 May;12(3):339-47
interleukin-6, 2-nitrophenylsulfenyl-Trp(36,160)  0   Interleukin-6/*analogs & derivatives. Eur J Biochem 1993 Oct 1;217(1):53-9
DAB(389)-interleukin 6  0   *Diphtheria Toxin *Interleukin-6 Recombinant Fusion Proteins. Protein Eng 1993 Apr;6(3):305-11
interleukin-6-PE66(4Glu) chimeric protein, recombinant  0   *Exotoxins *Recombinant Fusion Proteins *Interleukin-6 *ADP Ribose Transferases. Cancer Res 1991;51(11):2831
IL-6-PE40 protein, chimeric  0   *Exotoxins *Recombinant Fusion Proteins *Interleukin-6 *ADP Ribose Transferases Bacterial Proteins. Mol Cell Biol 1990;10(6):2443

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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