encyclopedia of medical concepts
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Interleukin-2
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Definition
: A soluble substance elaborated by antigen- or mitogen-stimulated T-LYMPHOCYTES which induces DNA synthesis in naive lymphocytes.
DF: IL 2 or IL2
Pharmacological Action
Analgesics, Non-Narcotic
;
Antineoplastic Agents
See Also
Receptors, Interleukin-2
Other names
TCGF; T-
Cell Growth Factor; Lymphocyte Mitogenic Factor; IL-
2; IL2; T Cell Stimulating Factor; T Cell Growth Factor; Ro236019; Ro 236019; Ro 23 6019; RU49637; Mitogenic Factor, Lymphocyte; Interleukin 2; Thymocyte Stimulating Factor; T-
Cell Stimulating Factor; Ro-
236019; Ro-
23-
6019; RU-
49637; RU 49637; Interleukine 2
Substance
CAS Registry & name
Categories
Source
Drugs
*
IL2 protein, human
0
*Interleukin-2.
NHS76-
PEP2
0
*Antibodies, Monoclonal
*Peptide Fragments
Interleukin-2.
Clin Cancer Res 2005 Apr 15;11(8):3084-93
tucotuzumab celmoleukin
339986-90-2
Interleukin-2/*analogs & derivatives.
J Immunother 2004 May-Jun;27(3):232-9
EMD 273063 antibody, human
0
*Antibodies, Monoclonal
*Interleukin-2.
J Clin Oncol. 2004 Nov 15;22(22):4463-73
technetium Tc 99m interleukin 2
0
*Interleukin-2
*Organotechnetium Compounds
Radiopharmaceuticals.
Eur J Nucl Med Mol Imaging 2003 Mar;30(3):374-82
interleukin-
2 (22-
58)
0
*Interleukin-2
*Peptide Fragments.
J Natl Cancer Inst 2003 May 21;95(10):741-9
oncolipin
0
*Interleukin-2
*Serum Albumin.
Cytokine. 2000 Nov;12(11):1691-701
recombinant fusion protein RNase1-
IL-
2
0
*Interleukin-2
*Ribonuclease, Pancreatic
Recombinant Fusion Proteins
Immunotoxins.
Cytokine 2000 Jun;12(6):786-90
peptide C-
I-
6
0
*Interleukin-2
*Peptide Fragments.
Eksp Klin Farmakol 1997 Jul-Aug;60(4):74-5
methionyl interleukin-
2, alanine(125)
0
Interleukin-2/*analogs & derivatives
Recombinant Proteins.
Hum Exp Toxicol 1995 Nov;14(11):909
recombinant fusion protein IL-
6 -
IL-
2
0
*Interleukin-2
*Interleukin-6
Recombinant Fusion Proteins.
Stem Cells (Dayt) 1994 May;12(3):339-47
aldesleukin
110942-02-4 2-
133-
Interleukin 2 (human reduced), 125-
L-
serine
Interleukin-2/*analogs & derivatives
Recombinant Proteins.
Pharma Action
Antineoplastic Agents
;
Anti-HIV Agents
Drug Ther Bull 1993 Apr 13;31(8):29-30
PROLEUKIN
interleukin-
2 (66-
72)
0
*Interleukin-2
*Peptide Fragments.
Bioorg Khim 1993 Jan;19(1):21-32
F42A
0
Interleukin-2/*analogs & derivatives.
J Immunol 1993 Apr 15;150(8 Pt 1):3357-65
denileukin diftitox
173146-27-5
*Diphtheria Toxin
*Interleukin-2
Recombinant Fusion Proteins.
Pharma Action
Antineoplastic Agents
J Acquir Immune Defic Syndr 1992 Dec;5(12):1181-7
ONTAK
interleukin-
2, succinyl
0
Interleukin-2/*analogs & derivatives.
Biotechnology 1990;8(8):755
interleukin-
2, polyethylene glycol-
modified
0
Interleukin-2/*analogs & derivatives
Polyethylene Glycols
Drug Carriers.
Biotechnology 1990;8(8):755
interleukin 2-
PE66(4Glu) protein, recombinant
0
*Exotoxins
*Interleukin-2
*Recombinant Fusion Proteins
Bacterial Proteins.
J Biol Chem 1990;265(27):16311
interleukin 2-
diphtheria toxin
0
*Diphtheria Toxin
*Interleukin-2
Recombinant Fusion Proteins.
Int J Cancer 1990;45(1):163
IL-
2-
PE40 chimeric protein, recombinant
0
*Exotoxins
*Interleukin-2
*Recombinant Proteins
Immunotoxins
Bacterial Proteins.
J Immunol 1988;141(12):4224
DAB(486)-
interleukin 2
0
*Diphtheria Toxin
*Interleukin-2
Recombinant Fusion Proteins
Immunotoxins.
Pharma Action
Antineoplastic Agents
;
Antirheumatic Agents
Am J Kid Dis 1988;11(2):159
Ala(125)-
interleukin 2
0
Interleukin-2/*analogs & derivatives.
Biochemistry 1986;25(25):8274
interleukin 2, glycosylated
0
Interleukin-2/*analogs & derivatives.
Carbohydr Res 1986;149(2):443
interleukin-
2 (59-
72)
90686-89-8
*Interleukin-2
*Peptide Fragments.
Cell Immunol 1985;94(2):491
interleukin 2 inhibitor
0
*Lymphokines
Interleukin-2/antagonists & inhibitors.
Immunology 1985;135(3):1834
PHILIP protein, human
0
*Glycoproteins
Interleukin-2.
Klin Wochenschr 1981;59(12):669
cytoplasmic activator protein, human
0
*Blood Proteins
Interleukin-2.
Life Sci 24(2):2441;1979
