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4-Aminopyridine

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Definition: One of the POTASSIUM CHANNEL BLOCKERS, with secondary effect on calcium currents, which is used mainly as a research tool and to characterize channel subtypes.     
Pharmacological Action Potassium Channel Blockers 		Other names VMI103; VMI 103; Sustained Release, 4-Aminopyridine; Fampridine SR; 4 Aminopyridine Sustained Release; 4 Aminopyridine; VMI-103; Pymadine; Fampridine-SR; 4-Aminopyridine Sustained Release
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-amino-5-bromopyridine  0   4-Aminopyridine/*analogs & derivatives. Rapid Commun Mass Spectrom 2003;17(13):1462-6
BM 14.1248  0   4-Aminopyridine/*analogs & derivatives. Structure 1996 Nov 15;4(11):1353-62
BM 51.1011  0   4-Aminopyridine/*analogs & derivatives. Structure 1996 Nov 15;4(11):1353-62
N,N'-(4-dimethylaminopyridine-2,6-diyl)-bis(histidine methyl ester)  0   Histidine/*analogs & derivatives 4-Aminopyridine/*analogs & derivatives. J Med Chem 1994 Dec 9;37(25):4267-9
3-methoxy-4-aminopyridine  52334-90-4   4-Aminopyridine/*analogs & derivatives. Neuropharmacology 1989;28(2):191
phenaridine  42045-97-6   4-Aminopyridine/*analogs & derivatives. Friziol Zh SSSR 1987;73(9):1160
nivalin P  53321-09-8   *Galantamine *4-Aminopyridine Drug Combinations. Eksp Med Morfol 1986;25(3):28
2,4-diamino-5-cyano-6-iodopyridine  70172-54-2   4-Aminopyridine/*analogs & derivatives 3',5'-Cyclic-AMP Phosphodiesterases/antagonists & inhibitors. Biochem Pharmacol 1984;33(13):2109
2,4-diamino-5-cyano-6-bromopyridine  42530-03-0   4-Aminopyridine/*analogs & derivatives Bronchodilator Agents 3',5'-Cyclic-AMP Phosphodiesterases/antagonists & inhibitors. Biochem Pharmacol 1984;33(13):2109
LF 14  88404-01-7   4-Aminopyridine/*analogs & derivatives. Eur J Pharmacol 1983;94(3-4):353
3-methyl-4-aminopyridine  1990-90-5   4-Aminopyridine/*analogs & derivatives. Anal Biochem 1981;113(1):139
2,4-diaminopyridine  461-88-1   4-Aminopyridine/*analogs & derivatives. Biochemistry 1980;19(5):3732
3,4-diaminopyridine  54-96-6   4-Aminopyridine/*analogs & derivatives Potassium Channels.
Pharma Action Potassium Channel Blockers 		Biophys J 22(3):507;1978; Clin Exp Pharmacol Physiol 6(2):159;1979; Eur J Pharmacol 1980;61(1):25; J Pharm Pharm 30(4):249;1978
4-dimethylaminopyridine  1122-58-3   4-Aminopyridine/*analogs & derivatives. J Chromatogr 121(1):41;1976; J Pharm Sci 62(5):845;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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