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Nitrofurans

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Definition:   urinary anti-infectives   
Examples 5-Amino-3-((5-nitro-2-furyl)vinyl)-1,2,4-oxadiazole; FANFT; Furagin; Furazolidone; Furylfuramide; Nifuratel; Nifurtimox; Nitrofurantoin; Nitrofurazone; Nitrovin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
5-nitro-2-furfurilylidene benzhydrazide  0   *Hydrazones *Nitrofurans. Pharm Dev Technol 2007;12(2):183-92
ethyl 3-cyano-4-(5'-nitro-2'-furyl)-2,6-dimethyl-1,4-dihydropyridine-5-carboxylate  0   *Nitrofurans Niacin/*analogs & derivatives. Bioelectrochemistry 2006 Sep;69(1):104-12
3,5-dicyano-4-(5'-nitro-2'-furyl)-2,6-dimethyl-1,4-dihydropyridine  0   *Dihydropyridines *Nitrofurans. Bioelectrochemistry 2006 Sep;69(1):104-12
ethyl 4-(5'-nitro-2'-furyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate  0   *Dihydropyridines *Nitrofurans. Bioelectrochemistry 2006 Sep;69(1):104-12
3-(5-nitrofuryl)-7-(5-nitrofurfurylidene)-3,3a,4,5,6,7-hexahydro-2H-indazole  0   *Indazoles *Nitrofurans. Antibiot Khimioter. 2005;50(2-3):18-21
5-nitro-2-furylpropionamide  39965-26-9 2-Furanpropanamide, 5-nitro  *Nitrofurans. Yao Hsueh Hsueh Pao 1982;17(5):349
nitrofurylacrylic acid  6281-23-8 3-(5-nitro-2-furanyl)-2-propenoic acid  *Acrylates *Nitrofurans.
Pharma Action Anti-Infective Agents ; Mutagens 		Mutat Res 1980;77(1):1; Mutat Res 1980;77(1):13; Mutat Res 68(4):367;1979; Neoplasma 1979;26(3):267
5,5-dimethyl-2-(5-nitrofuran-2-yl)-4-phenyl-1,3-dioxane  0   *Dioxanes *Nitrofurans. Anticancer Drug Des 1998 Sep;13(6):655-62
2-(5-nitrofuran-2-yl)-4-phenyl-1,3-dioxolane  0   *Dioxolanes *Nitrofurans. Anticancer Drug Des 1998 Sep;13(6):655-62
nifurpipone  24632-47-1   *Nitrofurans.
difuracil  0   Nitrofurans. Antibiot Khimioter 1995 Apr;40(4):34-6
1-(5-nitro-2-furyl)-2-(phenylsulfonyl)-2-(furylcarbonyl)ethylene  0   *Nitrofurans. Gen Physiol Biophys 1994 Oct;13(5):433-41
chinifur  70762-66-2 4-Quinolinecarboxamide, N-(4-(diethylamino)-1-methylbutyl)-2-(2-(5-nitro-2-furanyl)ethenyl)  *Nitrofurans *Quinolines. Biochem Biophys Res Commun 1994 Oct 14;204(1):224-9
4-(5-nitrofurfurylideneamino)-3-(furan-2)-5-mercapto-1,2,4-triazole  146173-56-0   *Nitrofurans *Triazoles Schiff Bases. Yao Hsueh Hsueh Pao 1992;27(10):738-42
N(2)-(5-nitrofurfurylidene)formohydrazide-4-(3,5-dicyanophenyl)-6-ethoxy-2-pyridylimide  141480-75-3   *Nitrofurans *Pyridines. Pharmazie 1992 Feb;47(2):98-101
nifurstyrenic acid  1534-38-9   *Nitrofurans *Styrenes. Drug Metab Dispos 1992 Mar-Apr;20(2):226-33
N-(2,3-epoxypropyl)-3-(5-nitrofuran-2-yl)-propenamide  129423-20-7   *Nitrofurans. Int J Radiat Oncol Biol Phys 1992;22(4):697-700
2,3-epoxypropyl-5-nitrofuran-2-carboxylate  129423-12-7   *Nitrofurans. Int J Radiat Oncol Biol Phys 1992;22(4):697-700
nifuroxime  6236-05-1   *Nitrofurans.
RB 88712  0   *Nitrofurans. Radiat Res 124(1 Suppl):S44
RB 88716  143134-32-1   *Aziridines *Nitrofurans. Radiat Res 124(1 Suppl):S44
5-nitrofuryl-2-acrolein  1874-22-2   *Nitrofurans Occlusive Dressings. Oftalmol Zh 1989;(7):409
2-nitronaphtho(2,1-b)furan  69267-51-2   *Nitrofurans. Jpn J cancer Res 1987;78(6):565
7-methoxy-1-methyl-2-nitronaphtho(2,1-b)furan  86539-71-1   *Nitrofurans. Cancer Lett 1987;35(1):59
4-bromo-5-nitrofuran azomethine  104514-43-4   *Nitrofurans. Yao Hsueh Hsueh Pao 1986;21(6):434
N-(2-N-piperidinylethyl)-beta-(5-nitro-4-bromo-2-furyl)acrylamide  100037-00-1   *Nitrofurans. Yao Hsueh Hsueh Pao 1985;20(7):513
N-ethoxycarbonylmethyl-beta-(5-nitro-4-bromo-2-furyl)acrylamide  100036-98-4   *Nitrofurans. Yao Hsueh Hsueh Pao 1985;20(7):513
M 106  81031-67-6   *Nitrofurans. Radiobiologiia 1985;25(6):748
3-(5-nitrofurfurylideneamino)hydantoic acid  63981-22-6   *Hydantoins *Nitrofurans. J Pharm Sci 1985;74(1):100
M 279  92950-21-5   *Nitrofurans. Chung Kuo Yao Li Hsueh Pao 1984;5(3):207
M 280  92950-22-6   *Nitrofurans. Chung Kuo YaoLi Hsueh Pao 1984;5(3):207
(1-(5-nitro-2-furanyl)methyleneamino)imidazolin-2-one  555-84-0   *Nitrofurans. Chung Kuo Yao Li Hsueh Pao 1984;5(3):207
5-nitro-2-furyl-alpha,beta-dibromopropionamide  83186-58-7 2-Furanpropanamide, alpha,beta-dibromo-5-nitro  *Nitrofurans. Yao Hsueh Hsueh Pao 1982;17(5):349
methyl 5-nitro-2-furoate  1874-23-3   *Nitrofurans. Chem Pharm Bull (Tokyo) 1982;30(7):2647
2-nitro-7-bromonaphtho(2.1-b)furan  75965-73-0   *Nitrofurans. Carcinogenesis 1981;2(10):1039
furapyrimidone  75888-03-8   *Nitrofurans. Chung-Kuo Yao Li Hseuh Pao 1980;1(1):60
nifursol  16915-70-1   *Nitrofurans. J Assoc Off Anal Chem 1981;64(4):969
2-nitro-7-methoxynaphtho(2-1b)furan  75965-74-1 Naphtho(2,1-b)furan, 7-methoxy-2-nitro  *Nitrofurans.
Pharma Action Antineoplastic Agents ; Carcinogens ; Mutagens 		Mutat Res 1981;88(4):355
methyl 5-nitro-3,4-diphenylfuran-2-carboxylate  52101-39-0 2-Furancarboxylic acid, 5-nitro-3,4-diphenyl-, methyl ester  *Nitrofurans. Chem Pharm Bull (Tokyo) 1981;29(3):635
nifurzide  39978-42-2   *Nitrofurans. Antimicrob Agents Chemother 1981;19(3):477
VR-6  33590-70-4 2-((2-(5-nitro-2-furanyl)thieno(3,2-d)pyrimidin-4-yl)amino)ethanol  *Nitrofurans. Arch Toxicol 42(4):259;1979
utonex  78920-52-2 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17alpha)-, mixt. with N-(3,4-dihydro-3-(5-nitro-2-furanyl)-2H-1,2,4-benzothiadiazin-6-yl)acetamide S,S-dioxide  *Ethinyl Estradiol *Nitrofurans Drug Combinations. VM SAC 74(6):864;1979
nitrofurathiazide  56645-23-9 Nitrofurathiazide  *Nitrofurans. VMSAC 74(6):864;1979
S72055  22508-01-6   *Nitrofurans. Chin Med J (Engl) 4(6):440;1978
furaguanidin  300-25-4 5-nitrofurfurilidenaminoguanidine  *Nitrofurans. Jpn J Bub Health Nurs 33(2):94;1977
nifacell  0   *Cellulose *Nitrofurans Bandages. Klin Khir 12:24;1976
nifuroxazide  965-52-6   *Hydroxybenzoic Acids *Nitrofurans.
Pharma Action Anti-Infective Agents 		Agressologie 16(5):309;1975; Lille Med 21(7):614;1976
H 193  1553-59-9 4-(2-(5-nitro-2-furanyl)ethenyl)benzamide  *Nitrofurans. Mutat Res 38(3):215;1976
2-nitro-8-methoxynaphtho(2,1-b)furan  75965-75-2 Naphtho(2,1-b)furan, 8-methoxy-2-nitro  *Nitrofurans. Bull Cancer (Paris) 1981;68(4):328
2-(2-(5-nitro-2-furyl)vinyl)-8-(beta-(N,N-diethylamino)ethoxy)quinoline  54333-93-6   *Nitrofurans. Chem Pharm Bull (Tokyo) 22(10):2470;1974
nifurprazin  1614-20-6   *Nitrofurans. Mol Gen Genet 139(3):255;1975; Mutat Res 42(1):109;1977; Zentralbl Veterinaermed (B) 23(4):346;1976
nifuron  19819-47-7   *Nitrofurans *Nitrogen Mustard Compounds. Eksp Med Morfol 13(4):237;1974; Mikrobiol Zh 40(1):73;1978
thiofuradene  2240-21-3   *Nitrofurans *Imidazolidines.
nihydrazone  67-28-7   *Nitrofurans.
nidroxyzone  405-22-1   *Nitrofurans.
nifurmazole  18857-59-5 3-hydroxymethyl-1-((3-(5-nitro-2-furyl)allylidene)amino)hydantoin  *Hydantoins *Nitrofurans. Cancer Res 33(11):2894;1973
furazonal  13185-22-3 4-(5-nitro-2-furfurylidenamino)-4H-1,2,4-triazole  *Nitrofurans. Farm Zh 27(2):20;1972
furazolium chloride  5118-17-2 6,7-dihydro-3-(5-nitro-2-furyl-5H-imidazo(2,1-b)- thiazolium chloride  *Nitrofurans. Am J Hosp Pharm 32(6):599;1975
furapromide  1951-56-0 N-isopropyl-3-(5-nitro-2-furyl)acrylamide  *Nitrofurans. Chinese Med J 1:40;1974; Chinese Med J 3(2):103;1977; Mutation Res 48:37;1977; Mutation Res 55(1):43;1978; Yao Hsueh Hsueh Pao 1979;14(4):218
furaltadon  139-91-3 5-(4-morpholinomethyl)-3-(5-nitro-2-furfurylideneamino)-2-oxazolidinone  *Nitrofurans *Oxazolidinones.
Pharma Action Anti-Infective Agents, Urinary 		J Agr. Food Chem 24(5):984;1976; Z Mikrobiol Epidemiol Immunobiol 5:133;1975
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